Cas no 774239-05-3 (4-Pyridinecarboxaldehyde, 2-(dimethylamino)-)

4-Pyridinecarboxaldehyde, 2-(dimethylamino)-, is a versatile heterocyclic aldehyde featuring a dimethylamino substituent at the 2-position of the pyridine ring. This compound is particularly valuable in organic synthesis and pharmaceutical research due to its dual functional groups, which enable its use as a key intermediate in the preparation of complex molecules. The electron-donating dimethylamino group enhances reactivity in nucleophilic addition and condensation reactions, while the pyridine core contributes to coordination chemistry applications. Its well-defined structure and stability make it suitable for use in ligand design, catalysis, and the development of bioactive compounds. The compound is typically handled under standard laboratory conditions, ensuring consistent performance in synthetic workflows.
4-Pyridinecarboxaldehyde, 2-(dimethylamino)- structure
774239-05-3 structure
Product Name:4-Pyridinecarboxaldehyde, 2-(dimethylamino)-
CAS No:774239-05-3
MF:C8H10N2O
MW:150.177801609039
CID:1784384
PubChem ID:23106639
Update Time:2025-06-07

4-Pyridinecarboxaldehyde, 2-(dimethylamino)- Chemical and Physical Properties

Names and Identifiers

    • 4-Pyridinecarboxaldehyde, 2-(dimethylamino)-
    • 2-(dimethylamino)pyridine-4-carbaldehyde
    • 774239-05-3
    • 2-(Dimethylamino)-4-pyridinecarboxaldehyde
    • EN300-624233
    • AB62865
    • 2-(DIMETHYLAMINO)ISONICOTINALDEHYDE
    • AKOS006307062
    • Z1198306800
    • SCHEMBL4778442
    • DB-148553
    • Inchi: 1S/C8H10N2O/c1-10(2)8-5-7(6-11)3-4-9-8/h3-6H,1-2H3
    • InChI Key: VLKZHGOJZULFBA-UHFFFAOYSA-N
    • SMILES: O=CC1C=CN=C(C=1)N(C)C

Computed Properties

  • Exact Mass: 150.0794
  • Monoisotopic Mass: 150.079312947g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 2
  • Complexity: 136
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 0.8
  • Topological Polar Surface Area: 33.2?2

Experimental Properties

  • PSA: 33.2

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Additional information on 4-Pyridinecarboxaldehyde, 2-(dimethylamino)-

Comprehensive Overview of 4-Pyridinecarboxaldehyde, 2-(dimethylamino)- (CAS No. 774239-05-3)

4-Pyridinecarboxaldehyde, 2-(dimethylamino)- (CAS No. 774239-05-3) is a specialized organic compound that has garnered significant attention in the fields of pharmaceutical research, agrochemical development, and material science. This compound, characterized by its unique pyridine core and dimethylamino functional group, serves as a versatile intermediate in the synthesis of more complex molecules. Its molecular structure, which includes a reactive aldehyde group, makes it particularly valuable for constructing heterocyclic frameworks, a common requirement in modern drug discovery.

The growing interest in 4-Pyridinecarboxaldehyde, 2-(dimethylamino)- can be attributed to its role in the development of novel therapeutics. Researchers are increasingly exploring its potential in creating kinase inhibitors, which are pivotal in treating cancers and inflammatory diseases. The compound’s ability to act as a building block for bioactive molecules aligns with current trends in precision medicine and targeted drug delivery systems. Additionally, its applications extend to the synthesis of fluorescent probes, which are essential tools in bioimaging and diagnostic assays.

From an industrial perspective, CAS No. 774239-05-3 is recognized for its utility in high-value chemical synthesis. Its incorporation into agrochemical formulations, such as plant growth regulators and pest control agents, highlights its importance in sustainable agriculture. The compound’s reactivity also makes it a candidate for developing advanced materials, including polymers with tailored properties for electronics and coatings. This versatility ensures its relevance in multiple sectors, driving demand among manufacturers and researchers alike.

One of the most frequently asked questions about 4-Pyridinecarboxaldehyde, 2-(dimethylamino)- revolves around its synthetic pathways and scalability. Recent advancements in catalytic methods have improved the efficiency of its production, reducing costs and environmental impact. Innovations such as flow chemistry and green chemistry principles are being applied to optimize its synthesis, addressing concerns about sustainability in the chemical industry. These developments are particularly relevant given the increasing focus on ESG (Environmental, Social, and Governance) criteria in corporate decision-making.

Another area of interest is the compound’s physicochemical properties, which influence its handling and application. Studies have detailed its solubility, stability, and reactivity under various conditions, providing valuable insights for formulators and process engineers. For instance, its compatibility with aqueous and organic solvents makes it adaptable to diverse reaction environments, a feature highly prized in multi-step synthetic routes. Such data is critical for ensuring reproducibility and safety in laboratory and industrial settings.

In the context of intellectual property, CAS No. 774239-05-3 has been featured in numerous patents, underscoring its commercial significance. Companies are actively investing in proprietary technologies to leverage its potential, particularly in drug discovery platforms and specialty chemicals. This competitive landscape reflects the compound’s strategic value, with stakeholders keen to capitalize on its multifunctional attributes.

Looking ahead, the trajectory for 4-Pyridinecarboxaldehyde, 2-(dimethylamino)- appears promising. As interdisciplinary research continues to uncover new applications, its role in emerging technologies such as nanomedicine and smart materials is expected to expand. Collaborative efforts between academia and industry will likely drive further innovation, ensuring that this compound remains at the forefront of scientific and industrial progress.

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