Cas no 766-47-2 (2-Methylphenylacetylene)

2-Methylphenylacetylene (CAS 766-81-0) is an aromatic alkyne derivative characterized by a methyl-substituted phenyl ring attached to an acetylene group. This compound serves as a versatile intermediate in organic synthesis, particularly in the preparation of pharmaceuticals, agrochemicals, and specialty materials. Its terminal alkyne functionality enables efficient participation in coupling reactions, such as Sonogashira and Click chemistry, facilitating the construction of complex molecular architectures. The methyl group enhances steric and electronic modulation, making it useful in regioselective transformations. With high purity and stability under standard conditions, 2-Methylphenylacetylene is a reliable reagent for research and industrial applications requiring precise functionalization of aromatic systems.
2-Methylphenylacetylene structure
2-Methylphenylacetylene structure
Product Name:2-Methylphenylacetylene
CAS No:766-47-2
MF:C9H8
MW:116.159822463989
MDL:MFCD03427202
CID:39807
PubChem ID:136598
Update Time:2025-05-19

2-Methylphenylacetylene Chemical and Physical Properties

Names and Identifiers

    • 2-Methylphenylacetylene
    • 2-Ethynyltoluene
    • 1-ethynyl-2-methylbenzene
    • Benzene, 1-ethynyl-2-methyl-
    • MFCD03427202
    • AKOS010651594
    • EN300-101008
    • BCP27272
    • toluylacetylene
    • CS-W013609
    • DTXSID50227407
    • 2-Ethynyltoluene, 97%
    • A15798
    • ethynyltoluene
    • 1-Ethynyl-2-methylbenzene #
    • Benzene,1-ethynyl-2-methyl-
    • SY253599
    • FT-0648874
    • 2-ETHYNYLTOLUENE97
    • 2-Ethynyl toluene
    • 766-47-2
    • 1-ethynyl-2-methyl-benzene
    • AS-33246
    • DB-240385
    • DB-075155
    • DTXCID10149898
    • AAA76647
    • MDL: MFCD03427202
    • Inchi: 1S/C9H8/c1-3-9-7-5-4-6-8(9)2/h1,4-7H,2H3
    • InChI Key: MYBSUWNEMXUTAX-UHFFFAOYSA-N
    • SMILES: C1(C)C=CC=CC=1C#C

Computed Properties

  • Exact Mass: 116.06300
  • Monoisotopic Mass: 116.0626
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 0
  • Heavy Atom Count: 9
  • Rotatable Bond Count: 0
  • Complexity: 126
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: 2.5
  • Topological Polar Surface Area: 0

Experimental Properties

  • Color/Form: Not determined
  • Density: 0.922?g/mL?at 25?°C(lit.)
  • Boiling Point: 50-60?°C/30?mmHg(lit.)
  • Flash Point: Fahrenheit: 95 ° f < br / > Celsius: 35 ° C < br / >
  • Refractive Index: n20/D 1.5470(lit.)
  • PSA: 0.00000
  • LogP: 1.97630
  • Solubility: Not determined

2-Methylphenylacetylene Security Information

2-Methylphenylacetylene Customs Data

  • HS CODE:2902909090
  • Customs Data:

    China Customs Code:

    2902909090

    Overview:

    2902909090. Other aromatic hydrocarbons. VAT:17.0%. Tax refund rate:9.0%. Regulatory conditions:nothing. MFN tariff:2.0%. general tariff:30.0%

    Declaration elements:

    Product Name, component content

    Summary:

    2902909090 other aromatic hydrocarbons.Supervision conditions:None.VAT:17.0%.Tax rebate rate:9.0%.MFN tariff:2.0%.General tariff:30.0%

2-Methylphenylacetylene Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
SHANG HAI XIAN DING Biotechnology Co., Ltd.
L-XV647-5ml
2-Methylphenylacetylene
766-47-2 98%
5ml
¥1680.0 2022-09-28
SHANG HAI XIAN DING Biotechnology Co., Ltd.
L-XV647-1ml
2-Methylphenylacetylene
766-47-2 98%
1ml
¥490.0 2022-09-28
Alichem
A019150929-5g
2-Ethynyltoluene
766-47-2 95%
5g
$289.80 2023-08-31
Alichem
A019150929-25g
2-Ethynyltoluene
766-47-2 95%
25g
$878.74 2023-08-31
Fluorochem
046078-1g
2-Methylphenylacetylene
766-47-2 95%
1g
£61.00 2022-03-01
Fluorochem
046078-5g
2-Methylphenylacetylene
766-47-2 95%
5g
£181.00 2022-03-01
Fluorochem
046078-10g
2-Methylphenylacetylene
766-47-2 95%
10g
£349.00 2022-03-01
Fluorochem
046078-25g
2-Methylphenylacetylene
766-47-2 95%
25g
£697.00 2022-03-01
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.
E117998-5ml
2-Methylphenylacetylene
766-47-2 98%
5ml
¥352.90 2023-09-03
SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd.
E117998-1ml
2-Methylphenylacetylene
766-47-2 98%
1ml
¥87.90 2023-09-03

2-Methylphenylacetylene Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:766-47-2)2-Methylphenylacetylene
Order Number:A15798
Stock Status:in Stock
Quantity:25g
Purity:99%
Pricing Information Last Updated:Monday, 2 September 2024 16:00
Price ($):183.0

Additional information on 2-Methylphenylacetylene

2-Methylphenylacetylene (CAS No. 766-47-2): Properties, Applications, and Market Insights

2-Methylphenylacetylene (CAS No. 766-47-2), also known as o-tolylacetylene, is a versatile organic compound widely used in chemical synthesis and pharmaceutical research. This aromatic alkyne is characterized by its unique structure, featuring a methyl group adjacent to the acetylene functionality on a benzene ring. Its molecular formula is C9H8, and it has a molecular weight of 116.16 g/mol. The compound is a colorless to pale yellow liquid at room temperature, with a distinctive aromatic odor.

The chemical properties of 2-Methylphenylacetylene make it a valuable intermediate in organic synthesis. Its terminal alkyne group is highly reactive, allowing it to participate in various coupling reactions, such as the Sonogashira coupling, click chemistry, and cycloaddition reactions. These reactions are crucial in the development of pharmaceuticals, agrochemicals, and advanced materials. Researchers often search for "2-Methylphenylacetylene uses in organic synthesis" or "CAS 766-47-2 applications" to explore its potential in their projects.

One of the most significant applications of 2-Methylphenylacetylene is in the pharmaceutical industry. It serves as a key building block for the synthesis of bioactive molecules, including potential drug candidates. Recent studies have highlighted its role in the development of anticancer agents and anti-inflammatory compounds. The compound's ability to form complex structures through palladium-catalyzed reactions has made it a favorite among medicinal chemists. Searches like "2-Methylphenylacetylene in drug discovery" reflect the growing interest in this area.

In addition to pharmaceuticals, 2-Methylphenylacetylene finds applications in material science. Its incorporation into polymers and coatings can enhance their mechanical and thermal properties. The compound's conjugated system makes it suitable for use in organic electronics, such as OLEDs and photovoltaic cells. Queries such as "2-Methylphenylacetylene in material science" or "o-tolylacetylene for organic electronics" are becoming increasingly common in academic and industrial research.

The market for 2-Methylphenylacetylene is expanding, driven by its diverse applications and the growing demand for fine chemicals. Suppliers and manufacturers are focusing on improving production methods to meet the needs of research institutions and industries. Topics like "2-Methylphenylacetylene suppliers" and "CAS 766-47-2 price trends" are frequently searched by buyers and procurement specialists. The compound is typically available in high purity grades, ensuring consistent performance in sensitive applications.

Safety and handling of 2-Methylphenylacetylene are critical considerations in laboratory and industrial settings. While it is not classified as a hazardous material under standard regulations, proper storage and handling procedures should be followed to prevent exposure. The compound should be kept in a cool, dry place, away from strong oxidizing agents. Researchers often look for "2-Methylphenylacetylene safety data" or "o-tolylacetylene handling precautions" to ensure compliance with safety protocols.

Recent advancements in synthetic chemistry have further highlighted the importance of 2-Methylphenylacetylene. Its role in green chemistry initiatives, where researchers aim to develop more sustainable and efficient synthetic routes, is gaining attention. Searches like "2-Methylphenylacetylene in green synthesis" or "CAS 766-47-2 sustainable applications" reflect this trend. The compound's compatibility with catalytic processes reduces waste and energy consumption, aligning with global sustainability goals.

In conclusion, 2-Methylphenylacetylene (CAS No. 766-47-2) is a multifaceted compound with significant applications in pharmaceuticals, material science, and beyond. Its unique chemical properties and reactivity make it indispensable in modern research and industrial processes. As interest in organic synthesis and sustainable chemistry grows, the demand for 2-Methylphenylacetylene is expected to rise, solidifying its position as a key player in the chemical industry.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:766-47-2)2-Methylphenylacetylene
A15798
Purity:99%
Quantity:25g
Price ($):183.0
Email