• 1. Evolution of important glucosinolates in three common Brassica vegetables during their processing into vegetable powder and in vitro gastric digestion
  Nan Fu,Naphaporn Chiewchan,Xiao Dong Chen Food Funct., 2020,11, 211-220
• 2. Dissociation of large gaseous serine clusters produces abundant protonated serine octamer
  Jacob S. Jordan,Evan R. Williams Analyst, 2021,146, 2617-2625
• 3. Excitation dependent bidirectional electron transfer in phthalocyanine-functionalised MoS2 nanosheets?
  Christopher J. Harrison,Kyle J. Berean,Enrico Della Gaspera,Jian Zhen Ou,Richard B. Kaner,Kourosh Kalantar-zadeh,Torben Daeneke Nanoscale, 2016,8, 16276-16283
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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Pyridine carboxaldehydes

Comprehensive Guide to 6-(Dimethylamino)-4-methylpyridine-3-carbaldehyde (CAS No. 764651-69-6)

6-(Dimethylamino)-4-methylpyridine-3-carbaldehyde (CAS No. 764651-69-6) is a versatile organic compound widely used in pharmaceutical research, agrochemical synthesis, and material science. This pyridine derivative features a unique combination of functional groups, including a dimethylamino group and an aldehyde moiety, making it a valuable intermediate in complex chemical syntheses. Researchers often search for "6-(Dimethylamino)-4-methylpyridine-3-carbaldehyde uses" or "764651-69-6 synthesis applications," reflecting its growing importance in modern chemistry.

The compound's molecular structure contributes to its reactivity and solubility properties. With a molecular formula of C₉H₁₂N₂O, 6-(Dimethylamino)-4-methylpyridine-3-carbaldehyde demonstrates excellent solubility in common organic solvents like dimethyl sulfoxide (DMSO) and dichloromethane. Recent trends in chemical research show increasing interest in "pyridine aldehyde derivatives in drug discovery" and "heterocyclic aldehyde applications," positioning this compound as a focus area for medicinal chemistry development.

In pharmaceutical applications, 6-(Dimethylamino)-4-methylpyridine-3-carbaldehyde serves as a crucial building block for various bioactive molecules. The compound's aldehyde functionality allows for diverse chemical transformations, including condensation reactions to form Schiff bases, which are valuable in developing new therapeutic agents. Current research hotspots include "pyridine-based drug candidates 2024" and "small molecule modulators using aldehyde intermediates," areas where this compound shows significant potential.

The material science field has also recognized the value of 764651-69-6, particularly in developing advanced coordination polymers and metal-organic frameworks (MOFs). The compound's ability to act as a multidentate ligand makes it attractive for creating novel materials with specific electronic or catalytic properties. Industry searches for "functionalized pyridines for MOF synthesis" and "nitrogen-containing ligands for catalysis" highlight these emerging applications.

From a synthetic chemistry perspective, 6-(Dimethylamino)-4-methylpyridine-3-carbaldehyde offers several advantages. Its electron-rich pyridine ring facilitates various electrophilic substitution reactions, while the dimethylamino group enhances solubility and modifies electronic properties. These characteristics answer common search queries like "how to modify pyridine aldehydes" and "directing groups for regioselective reactions," making it a popular subject in organic chemistry discussions.

Quality control and analytical characterization of 764651-69-6 typically involve advanced techniques such as high-performance liquid chromatography (HPLC), nuclear magnetic resonance (NMR) spectroscopy, and mass spectrometry. The compound's purity is crucial for research applications, as evidenced by frequent searches for "analytical methods for pyridine aldehydes" and "CAS 764651-69-6 purity standards." Reputable suppliers provide comprehensive certificates of analysis to meet these research requirements.

The commercial availability of 6-(Dimethylamino)-4-methylpyridine-3-carbaldehyde has increased significantly in recent years, with global suppliers offering the compound in various quantities. Market trends show growing demand for "custom synthesis of pyridine derivatives" and "bulk quantities of specialty aldehydes," reflecting its expanding applications. Proper storage conditions (typically 2-8°C in airtight containers) ensure the compound's stability and longevity.

Environmental and safety considerations for 764651-69-6 follow standard laboratory chemical protocols. While not classified as hazardous under current regulations, proper handling procedures are essential, including the use of personal protective equipment (PPE) and adequate ventilation. These precautions address common safety-related searches such as "pyridine aldehyde handling precautions" and "chemical stability of 6-(Dimethylamino)-4-methylpyridine-3-carbaldehyde."

Future research directions for 6-(Dimethylamino)-4-methylpyridine-3-carbaldehyde include exploring its potential in asymmetric catalysis and photocatalytic systems. The compound's structural features make it a candidate for developing new organocatalysts and light-responsive materials. These applications align with current scientific interests in "sustainable chemical processes" and "green chemistry alternatives," ensuring continued relevance in chemical research.

In summary, 6-(Dimethylamino)-4-methylpyridine-3-carbaldehyde (CAS No. 764651-69-6) represents an important chemical building block with diverse applications across multiple scientific disciplines. Its unique combination of functional groups and reactivity patterns continues to attract research attention, particularly in areas addressing current challenges in medicinal chemistry, materials science, and sustainable synthesis. The compound's versatility ensures its ongoing importance in scientific innovation and industrial applications.

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