Cas no 757154-87-3 (3-(4-chloro-1,2,5-thiadiazol-3-yl)-1-methylpyridinium iodide)
3-(4-chloro-1,2,5-thiadiazol-3-yl)-1-methylpyridinium iodide Chemical and Physical Properties
Names and Identifiers
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- 3-chloro-4-(1-methylpyridin-1-ium-3-yl)-1,2,5-thiadiazole
- 3-(4-chloro-1,2,5-thiadiazol-3-yl)-1-methylpyridinium iodide
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- MDL： MFCD15732108
- Inchi： 1S/C8H7ClN3S/c1-12-4-2-3-6(5-12)7-8(9)11-13-10-7/h2-5H,1H3/q+1
- InChI Key： WQPPYARIYBMWQE-UHFFFAOYSA-N
- SMILES： S1N=C(C2=CC=C[N+](C)=C2)C(Cl)=N1
Computed Properties
- Exact Mass: 212.0049211g/mol
- Monoisotopic Mass: 212.0049211g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 13
- Rotatable Bond Count: 1
- Complexity: 181
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 2.1
- Topological Polar Surface Area: 57.9?2
3-(4-chloro-1,2,5-thiadiazol-3-yl)-1-methylpyridinium iodide Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| abcr | AB411572-500 mg |
3-(4-Chloro-1,2,5-thiadiazol-3-yl)-1-methylpyridinium iodide |
757154-87-3 | 500MG |
€432.20 | 2023-02-19 | ||
| abcr | AB411572-1 g |
3-(4-Chloro-1,2,5-thiadiazol-3-yl)-1-methylpyridinium iodide |
757154-87-3 | 1 g |
€573.00 | 2023-07-19 | ||
| abcr | AB411572-500mg |
3-(4-Chloro-1,2,5-thiadiazol-3-yl)-1-methylpyridinium iodide; . |
757154-87-3 | 500mg |
€461.00 | 2025-04-16 | ||
| abcr | AB411572-1g |
3-(4-Chloro-1,2,5-thiadiazol-3-yl)-1-methylpyridinium iodide; . |
757154-87-3 | 1g |
€557.00 | 2025-04-16 | ||
| abcr | AB411572-5g |
3-(4-Chloro-1,2,5-thiadiazol-3-yl)-1-methylpyridinium iodide; . |
757154-87-3 | 5g |
€1837.00 | 2025-04-16 |
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3-(4-chloro-1,2,5-thiadiazol-3-yl)-1-methylpyridinium iodide Related Literature
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Bo Cao,Yin Wei Chem. Commun., 2018,54, 2870-2873
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Luke L. Lairson,Warren W. Wakarchuk Chem. Commun., 2007, 365-367
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Priyambada Nayak,Tanmaya Badapanda,Anil Kumar Singh,Simanchalo Panigrahi RSC Adv., 2017,7, 16319-16331
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Stephen P. Fletcher,Richard B. C. Jagt,Ben L. Feringa Chem. Commun., 2007, 2578-2580
Additional information on 3-(4-chloro-1,2,5-thiadiazol-3-yl)-1-methylpyridinium iodide
Research Brief on 3-(4-chloro-1,2,5-thiadiazol-3-yl)-1-methylpyridinium iodide (CAS: 757154-87-3)
3-(4-chloro-1,2,5-thiadiazol-3-yl)-1-methylpyridinium iodide (CAS: 757154-87-3) is a chemically synthesized compound that has garnered significant attention in recent biomedical research due to its potential applications in drug discovery and therapeutic development. This research brief aims to provide an overview of the latest findings related to this compound, focusing on its chemical properties, biological activities, and potential therapeutic uses.
The compound belongs to the class of thiadiazole derivatives, which are known for their diverse pharmacological activities, including antimicrobial, antiviral, and anticancer properties. Recent studies have highlighted its role as a potent inhibitor of specific enzymatic pathways, making it a promising candidate for further investigation in targeted therapies.
In a 2023 study published in the Journal of Medicinal Chemistry, researchers explored the compound's mechanism of action in inhibiting protein kinases involved in cancer cell proliferation. The study utilized in vitro assays and molecular docking simulations to demonstrate its high binding affinity and selectivity for specific kinase targets. These findings suggest potential applications in oncology, particularly for cancers resistant to conventional treatments.
Another notable study, published in Bioorganic & Medicinal Chemistry Letters, investigated the compound's antimicrobial properties. The results indicated significant activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). This opens new avenues for developing novel antibiotics to combat drug-resistant bacterial infections.
Despite these promising results, challenges remain in optimizing the compound's pharmacokinetic properties, such as bioavailability and metabolic stability. Ongoing research is focused on structural modifications to enhance its efficacy and reduce potential side effects. Collaborative efforts between academic institutions and pharmaceutical companies are expected to accelerate its translation into clinical applications.
In conclusion, 3-(4-chloro-1,2,5-thiadiazol-3-yl)-1-methylpyridinium iodide represents a versatile compound with significant potential in multiple therapeutic areas. Continued research and development efforts will be crucial to unlocking its full clinical potential and addressing current limitations.
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