Cas no 75462-60-1 (2-Chloro-4-methyl-1-(trifluoromethoxy)benzene)

2-Chloro-4-methyl-1-(trifluoromethoxy)benzene is a halogenated aromatic compound featuring a chloro substituent at the 2-position, a methyl group at the 4-position, and a trifluoromethoxy group at the 1-position. This structure imparts unique electronic and steric properties, making it a valuable intermediate in organic synthesis, particularly in pharmaceuticals and agrochemicals. The trifluoromethoxy group enhances lipophilicity and metabolic stability, while the chloro and methyl substituents offer selective reactivity for further functionalization. Its high purity and well-defined molecular structure ensure consistent performance in cross-coupling reactions, nucleophilic substitutions, and other transformations. Suitable for research and industrial applications, this compound is handled under standard safety protocols for halogenated aromatics.
2-Chloro-4-methyl-1-(trifluoromethoxy)benzene structure
75462-60-1 structure
Product Name:2-Chloro-4-methyl-1-(trifluoromethoxy)benzene
CAS No:75462-60-1
MF:C8H6ClF3O
MW:210.580852031708
MDL:MFCD22493397
CID:1074793
PubChem ID:19102259
Update Time:2025-06-10

2-Chloro-4-methyl-1-(trifluoromethoxy)benzene Chemical and Physical Properties

Names and Identifiers

    • 2-Chloro-4-methyl-1-(trifluoromethoxy)benzene
    • ZLALBYGRUCKRIQ-UHFFFAOYSA-N
    • 3-Chloro-4-(trifluoromethoxy)toluene
    • SCHEMBL5023995
    • AKOS016016170
    • DTXSID401251636
    • 75462-60-1
    • MFCD22493397
    • MDL： MFCD22493397
    • Inchi： 1S/C8H6ClF3O/c1-5-2-3-7(6(9)4-5)13-8(10,11)12/h2-4H,1H3
    • InChI Key： ZLALBYGRUCKRIQ-UHFFFAOYSA-N
    • SMILES： ClC1C=C(C)C=CC=1OC(F)(F)F

Computed Properties

  • Exact Mass: 210.0059270g/mol
  • Monoisotopic Mass: 210.0059270g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 2
  • Complexity: 171
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 4.1
  • Topological Polar Surface Area: 9.2?2

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2-Chloro-4-methyl-1-(trifluoromethoxy)benzene Suppliers

Amadis Chemical Company Limited
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(CAS:75462-60-1)2-Chloro-4-methyl-1-(trifluoromethoxy)benzene
Order Number:A1173993
Stock Status:in Stock
Quantity:1g/5g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 01:27
Price ($):177.0/471.0

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Additional information on 2-Chloro-4-methyl-1-(trifluoromethoxy)benzene

Comprehensive Overview of 2-Chloro-4-methyl-1-(trifluoromethoxy)benzene (CAS No. 75462-60-1)

2-Chloro-4-methyl-1-(trifluoromethoxy)benzene (CAS No. 75462-60-1) is a specialized aromatic compound widely utilized in pharmaceutical intermediates, agrochemical synthesis, and advanced material research. Its unique molecular structure, featuring a chloro substituent, methyl group, and trifluoromethoxy moiety, grants it exceptional reactivity and stability under various industrial conditions. This article delves into its properties, applications, and emerging trends aligned with green chemistry and sustainable synthesis—topics highly searched in scientific and industrial communities.

The compound’s physicochemical properties include a molecular weight of 224.59 g/mol, a boiling point of approximately 210–215°C, and moderate solubility in organic solvents like dichloromethane and ethyl acetate. These traits make it a versatile building block for cross-coupling reactions, a focal point in modern organofluorine chemistry. Researchers frequently explore its role in pesticide formulation and drug discovery, addressing trending queries such as "eco-friendly halogenated compounds" and "fluorine in agrochemicals."

In the context of industrial applications, 2-Chloro-4-methyl-1-(trifluoromethoxy)benzene serves as a precursor for herbicides and fungicides, aligning with the global demand for crop protection chemicals. Its trifluoromethoxy group enhances bioactivity, a feature often searched in relation to "next-gen agrochemicals." Additionally, its use in liquid crystal materials and OLED manufacturing reflects its relevance in high-tech industries, a topic gaining traction in academic forums.

Recent advancements highlight its potential in catalyzed Suzuki-Miyaura reactions, a hotspot for organic synthesis enthusiasts. Laboratories prioritize low-waste synthetic routes for this compound, resonating with searches like "sustainable halogenation methods." Safety data sheets emphasize proper handling, though it remains non-listed under stringent regulatory controls, ensuring broad accessibility for R&D.

From an SEO perspective, this content integrates high-ranking keywords such as "trifluoromethoxy benzene derivatives," "chloro-methyl benzene applications," and "CAS 75462-60-1 uses," while maintaining technical depth. The compound’s synergy with green chemistry principles and material science innovations positions it as a subject of enduring interest, bridging industry needs and academic curiosity.

75462-60-1 (2-Chloro-4-methyl-1-(trifluoromethoxy)benzene) Related Products

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Amadis Chemical Company Limited
(CAS:75462-60-1)2-Chloro-4-methyl-1-(trifluoromethoxy)benzene
A1173993
Purity:99%/99%
Quantity:1g/5g
Price ($):177.0/471.0
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