Production Method 1

939-57-1

752198-38-2

80126-53-0

Reaction Conditions

1.1 Reagents: Ammonia Catalysts: Aminomutase, phenylalanine 2,3- Solvents: Water ;  24 h, pH 10, 30 °C
1.2 5 min, 99 °C

Reference

Phenylalanine Aminomutase-Catalyzed Addition of Ammonia to Substituted Cinnamic Acids: A Route to Enantiopure α- and β-Amino Acids

Szymanski, Wiktor; et al, Journal of Organic Chemistry, 2009, 74(23), 9152-9157

(R)-3-Amino-3-(2-methylphenyl)propionic acid Raw materials

• 2-Methylcinnamic Acid, Predominantly trans

(R)-3-Amino-3-(2-methylphenyl)propionic acid Preparation Products

• (R)-3-Amino-3-(2-methylphenyl)propionic acid (752198-38-2)
• H-Phe(2-Me)-OH (80126-53-0)

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• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Amino acids, peptides, and analogues Amino acids and derivatives

• 490034-62-3((3S)-3-Amino-3-(2-methylphenyl)propanoic Acid Hydrochloride)
• 117391-55-6(3-Amino-3-(2,5-dimethylphenyl)propanoic Acid)
• 682804-03-1(3-amino-3-(2,4,6-trimethylphenyl)propanoic acid)
• 68208-16-2(β-Amino-2-methylbenzenepropanoic Acid)
• 117391-54-5(3-Amino-3-(2,4-dimethylphenyl)propanoic acid)
• 412925-12-3(3-Amino-3-(2,3-dimethylphenyl)propanoic acid)
• 736131-48-9((S)-3-Amino-3-(2-methyl-phenyl)-propionic acid)
• 299164-93-5(3-Amino-3-(2-ethylphenyl)propanoic Acid)
• 682803-45-8(3-amino-3-(2,3,4,5,6-pentamethylphenyl)propanoic Acid)
• 773122-62-6(3-(2,4,5-trimethylphenyl)-β-alanine)