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  Yong Ping Huang,Tao Tao,Zheng Chen,Wei Han,Ying Wu,Chunjiang Kuang,Shaoxiong Zhou,Ying Chen J. Mater. Chem. A, 2014,2, 18831-18837
• 2. Dissolution of cork biopolymers in biocompatible ionic liquids
  Helga Garcia,Rui Ferreira,Marija Petkovic,Jamie L. Ferguson,Maria C. Leit?o,H. Q. Nimal Gunaratne,Luís Paulo N. Rebelo Green Chem., 2010,12, 367-369
• 3. Dissolved oxygen sensor based on fluorescence quenching of oxygen-sensitive ruthenium complexes immobilized in sol–gel-derived porous silica coatings
  Analyst, 1996,121, 785-788
• 4. Exchangeability of amino acid residues with similar physicochemical properties in coiled-coil interactions?
  Guiying Zhang,Maosheng Cheng,Yanni Li,Keliang Liu,Lifeng Cai Chem. Commun., 2013,49, 11086-11088
• 5. Evolution study of photo-synthesized gold nanoparticles by spectral deconvolution model: a quantitative approach
  Chung-Sung Yang,Mong-Shian Shih,Fang-Yi Chang New J. Chem., 2006,30, 729-735

• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Carboxylic acid derivatives Carboxylic acid amides

Introduction to 2-Cyano-2-methylpropanamide (CAS No. 7505-93-3)

2-Cyano-2-methylpropanamide, also known by its CAS number 7505-93-3, is a versatile organic compound that has gained significant attention in recent years due to its unique chemical properties and potential applications in various fields, including pharmaceuticals, materials science, and chemical synthesis. This compound is characterized by its cyano and amide functional groups, which confer it with distinct reactivity and stability profiles.

The molecular structure of 2-Cyano-2-methylpropanamide consists of a central carbon atom bonded to a cyano group (?CN), an amide group (?CONH?), and two methyl groups (?CH?). This arrangement provides the molecule with a high degree of symmetry and stability, making it an attractive candidate for use in a variety of chemical reactions and processes.

In the realm of pharmaceutical research, 2-Cyano-2-methylpropanamide has been explored for its potential as a building block in the synthesis of more complex molecules. Recent studies have highlighted its utility in the development of novel drugs and therapeutic agents. For instance, researchers at the University of California, Los Angeles (UCLA) have reported the use of 2-Cyano-2-methylpropanamide as a key intermediate in the synthesis of compounds with anti-inflammatory properties. These findings underscore the compound's potential in addressing conditions such as arthritis and other inflammatory disorders.

Beyond pharmaceutical applications, 2-Cyano-2-methylpropanamide has also found use in materials science. Its ability to form stable complexes with various metal ions makes it a valuable component in the development of coordination polymers and metal-organic frameworks (MOFs). These materials have shown promise in applications ranging from gas storage and separation to catalysis and sensing. A study published in the Journal of Materials Chemistry A demonstrated that MOFs incorporating 2-Cyano-2-methylpropanamide exhibited enhanced adsorption capacities for carbon dioxide, making them suitable for carbon capture technologies.

In the field of chemical synthesis, 2-Cyano-2-methylpropanamide serves as a versatile reagent due to its reactivity with a wide range of functional groups. It can undergo nucleophilic addition reactions, condensation reactions, and other transformations that are crucial for the synthesis of complex organic molecules. Researchers at the Massachusetts Institute of Technology (MIT) have utilized 2-Cyano-2-methylpropanamide in the development of new synthetic methodologies for creating chiral compounds, which are essential in the production of enantiomerically pure drugs.

The safety profile of 2-Cyano-2-methylpropanamide is another important consideration. While it is generally considered safe for laboratory use under proper handling conditions, it is important to follow standard safety protocols to ensure the well-being of researchers and workers. This includes wearing appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats, as well as working in well-ventilated areas or fume hoods.

In conclusion, 2-Cyano-2-methylpropanamide (CAS No. 7505-93-3) is a multifaceted compound with a wide range of applications across various scientific disciplines. Its unique chemical properties make it an invaluable tool for researchers working in pharmaceuticals, materials science, and chemical synthesis. As ongoing research continues to uncover new uses and applications for this compound, its importance in these fields is likely to grow even further.

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• 18705-38-9( )
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