Cas no 74605-12-2 (4-(2,5-dimethoxyphenyl)-1,3-thiazol-2-amine)

4-(2,5-Dimethoxyphenyl)-1,3-thiazol-2-amine is a heterocyclic compound featuring a thiazole core substituted with an amine group at the 2-position and a 2,5-dimethoxyphenyl moiety at the 4-position. This structure imparts unique electronic and steric properties, making it a valuable intermediate in organic synthesis and medicinal chemistry. The dimethoxyphenyl group enhances solubility and modulates reactivity, while the thiazol-2-amine scaffold is known for its bioactivity, particularly in pharmaceutical applications. The compound is useful in the development of novel therapeutic agents, agrochemicals, and functional materials. Its well-defined synthetic pathway and stability under standard conditions further contribute to its utility in research and industrial applications.
4-(2,5-dimethoxyphenyl)-1,3-thiazol-2-amine structure
74605-12-2 structure
Product Name:4-(2,5-dimethoxyphenyl)-1,3-thiazol-2-amine
CAS No:74605-12-2
MF:C11H12N2O2S
MW:236.290181159973
MDL:MFCD02663891
CID:568200
PubChem ID:675262
Update Time:2025-10-16

4-(2,5-dimethoxyphenyl)-1,3-thiazol-2-amine Chemical and Physical Properties

Names and Identifiers

    • 4-(2,5-Dimethoxyphenyl)thiazol-2-amine
    • 2-Thiazolamine,4-(2,5-dimethoxyphenyl)-
    • 4-(2,5-dimethoxyphenyl)-1,3-thiazol-2-amine
    • 4-(2,5-Dimethoxy-phenyl)-thiazol-2-ylamine
    • F2146-0040
    • DTXSID90350187
    • EN300-06115
    • 74605-12-2
    • Z48847670
    • J-513265
    • MS-10999
    • MFCD02663891
    • SCHEMBL5327111
    • FT-0677866
    • SR-01000321826
    • Oprea1_479334
    • SR-01000321826-1
    • BB 0242824
    • BAS 05261530
    • AKOS000112484
    • STK398703
    • 4-(2,5-dimethoxyphenyl)-1,3-thiazol-2-ylamine
    • DB-028301
    • AK-968/41018035
    • G75961
    • ALBB-001836
    • BBL007995
    • MDL: MFCD02663891
    • Inchi: 1S/C11H12N2O2S/c1-14-7-3-4-10(15-2)8(5-7)9-6-16-11(12)13-9/h3-6H,1-2H3,(H2,12,13)
    • InChI Key: FXGVKHSZIMCUTR-UHFFFAOYSA-N
    • SMILES: S1C(N)=NC(=C1)C1C=C(C=CC=1OC)OC

Computed Properties

  • Exact Mass: 236.06200
  • Monoisotopic Mass: 236.06194880g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 16
  • Rotatable Bond Count: 3
  • Complexity: 230
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.2
  • Topological Polar Surface Area: 85.6?2

Experimental Properties

  • Density: 1.3±0.1 g/cm3
  • Melting Point: 113-115 °C
  • Boiling Point: 389.4±27.0 °C at 760 mmHg
  • Flash Point: 189.3±23.7 °C
  • Refractive Index: 1.608
  • PSA: 85.61000
  • LogP: 2.99070
  • Vapor Pressure: 0.0±0.9 mmHg at 25°C

4-(2,5-dimethoxyphenyl)-1,3-thiazol-2-amine Security Information

4-(2,5-dimethoxyphenyl)-1,3-thiazol-2-amine Customs Data

  • HS CODE:2934100090
  • Customs Data:

    China Customs Code:

    2934100090

    Overview:

    2934100090. Compounds that structurally contain a non fused thiazole ring(Whether hydrogenated or not). VAT:17.0%. Tax refund rate:9.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

4-(2,5-dimethoxyphenyl)-1,3-thiazol-2-amine Pricemore >>

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