Cas no 74389-69-8 (1-O-Octadecyl-2-O-acetyl-sn-glycero-3-phosphocholine)

1-O-Octadecyl-2-O-acetyl-sn-glycero-3-phosphocholine is a synthetic phospholipid derivative characterized by its ether-linked octadecyl chain at the sn-1 position and an acetyl group at the sn-2 position. This structure enhances its stability against enzymatic degradation, making it particularly useful in lipid membrane research and drug delivery systems. The phosphocholine headgroup confers amphiphilic properties, facilitating the formation of stable liposomes or micelles. Its synthetic purity and defined structure allow for precise experimental control in studies involving membrane dynamics, cell signaling, or targeted therapeutics. The compound’s resistance to phospholipases further expands its utility in long-term biological applications.
1-O-Octadecyl-2-O-acetyl-sn-glycero-3-phosphocholine structure
74389-69-8 structure
Product Name:1-O-Octadecyl-2-O-acetyl-sn-glycero-3-phosphocholine
CAS No:74389-69-8
MF:C28H58NO7P
MW:551.736390590668
MDL:MFCD00063528
CID:571279
PubChem ID:2733535
Update Time:2025-06-29

1-O-Octadecyl-2-O-acetyl-sn-glycero-3-phosphocholine Chemical and Physical Properties

Names and Identifiers

    • 3,5,9-Trioxa-4-phosphaheptacosan-1-aminium,7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-, inner salt, 4-oxide, (7R)-
    • 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine
    • [(2R)-2-acetyloxy-3-octadecoxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
    • 1-O-Octadecyl-2-O-acetyl-sn-glycero-3-phosphocholine
    • 3,5,9-Trioxa-4-phosphaheptacosan-1-aminium,7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-, inner sal...
    • NULL
    • PAF (C18)
    • PAF (C18) (1-O-OCTADECYL-2-ACETYL-SN-GLYCERO-3-PHOSPHOCHOLINE)
    • PAF C-18
    • [(2R)-2-acetyloxy-3-octadecoxypropyl] 2-(trimethylaz
    • 1-0-octadecyl 2-0-acetyl sn-glycero-3-phosphorylcholine
    • 1-O-Octadecyl-2-acetyl-sn-glyceryl-3-phosphorylcholine
    • 1-O-octadecyl-2-O-acetyl-Sn-3-glyceryl phosphrylcholine
    • 1-O-octadecyl-2-O-acetyl-sn-glycero-3-phosphorylcholine
    • 1-O-octadecyl-2-O-acetyl-sn-glyceryl-3-phosphorylcholine
    • 1-O-Stearoyl-2-acetyl-sn-glyceryl-3-phosphorylcholine
    • C18-PAF
    • Platelet activating factor-acether
    • Ro 14-8161
    • MFCD00063528
    • CHEBI:52450
    • NCGC00161375-01
    • HMS3648P16
    • (-)-1-O-octadeyl-2-O-acetyl-sn-glycerylphosphocholine
    • 3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-, inner salt, 4-oxide, (R)-
    • 1-cis-9-octadecenyl-2-acetyl-sn-glycero-3-phosphocholine
    • SCHEMBL435191
    • ZXCIEWBDUAPBJF-MUUNZHRXSA-N
    • (R)-2-Acetoxy-3-(octadecyloxy)propyl (2-(trimethylammonio)ethyl) phosphate
    • 1-O-octadecyl-PAF
    • 2-(Acetyloxy)-3-(octadecyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate
    • DTXSID80995900
    • NCGC00161375-02
    • 1-O-Octadecyl-platelet-activating factor
    • (2RR)-2-acetoxy-3-(octadecyloxy)propyl 2-(trimethylazaniumyl)ethyl phosphate
    • NCGC00161375-03
    • PAF(C18)
    • NS00074270
    • Q60998693
    • PAF C18
    • C9ZA6E5Q2B
    • acetyl-glyceryl-ether-phosphorylcholine
    • 3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-, inner salt, 4-oxide, (7R)-
    • AKOS037645012
    • C18:0 PAF
    • 1-octadecyl-2-acetyl-sn-glycero-3-phosphocholine
    • phosphatidylcholine (O-18:0/2:0)
    • HMS1361I12
    • AS-56132
    • Ro-14-8161
    • BML3-E05
    • 1-O-Stearyl-2-acetyl-sn-glyceryl-3-phosphorylcholine
    • C18-Paf-acether
    • (R)-2-acetoxy-3-(octadecyloxy)propyl 2-(trimethylammonio)ethyl phosphate
    • 1-O-octadecyl 2-O-acetyl sn-glycero-3-phosphorylcholine
    • C18-02:0 PC, 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine, chloroform
    • 2-CHLORO-1H-BENZIMIDAZOLE-5-CARBOXYLICACID
    • Blood platelet activating factor-aether
    • HMS1791I12
    • HMS3402I12
    • 3,5,9-Trioxo-4-phosphaheptacosan-1-aminium, 7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-, hydroxide, inner salt, 4-oxide, (R)-
    • CHEMBL1788194
    • (R)-7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-3,5,9-trioxa-4-phosphaheptaconasan-1-aminium hydroxide inner salt 4-oxide
    • LMGP01020094
    • 2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine
    • C18-02:0 PC, 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine, powder
    • HMS1989I12
    • 74389-69-8
    • PC(O-18:0/2:0)
    • (2R)-2-acetoxy-3-(octadecyloxy)propyl 2-(trimethylammonio)ethyl phosphate
    • 1-O-OCTADECYL-PLATELET ACTIVATING FACTOR
    • 1-o-octadecyl-2-acetoyl-sn-glycero-3-phosphocholine
    • G90853
    • MDL： MFCD00063528
    • Inchi： 1S/C28H58NO7P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-23-33-25-28(36-27(2)30)26-35-37(31,32)34-24-22-29(3,4)5/h28H,6-26H2,1-5H3/t28-/m1/s1
    • InChI Key： ZXCIEWBDUAPBJF-MUUNZHRXSA-N
    • SMILES： P(=O)([O-])(OC[C@@H](COCCCCCCCCCCCCCCCCCC)OC(C)=O)OCC[N+](C)(C)C

Computed Properties

  • Exact Mass: 551.39500
  • Monoisotopic Mass: 551.39509019g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 7
  • Heavy Atom Count: 37
  • Rotatable Bond Count: 28
  • Complexity: 575
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 1
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: 7.6
  • Topological Polar Surface Area: 94.1?2

Experimental Properties

  • Color/Form: Not available
  • Solubility: chloroform: 10?mg/mL
  • PSA: 103.93000
  • LogP: 7.47420
  • Color/Form: 5?mg/mL (878114C-5mg)
  • Solubility: Soluble in water

1-O-Octadecyl-2-O-acetyl-sn-glycero-3-phosphocholine Security Information

  • Hazardous Material transportation number：NONH for all modes of transport
  • WGK Germany：3
  • Safety Instruction： S24/25
  • Storage Condition：?20°C
  • Safety Term：S24/25

1-O-Octadecyl-2-O-acetyl-sn-glycero-3-phosphocholine Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd.
878114C-5MG
C18-02:0 PC
 74389-69-8 1-O-octadecyl-2-acetyl-
5MG
 1163.41 2021-05-14
XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd.
878114P-5MG
C18-02:0 PC
 74389-69-8
5mg
 ￥1522.2 2023-11-02
SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd.
O863867-5mg
1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine
 74389-69-8 >99%
5mg
 ￥2,027.70 2022-09-01
SHANG HAI XIAN DING Biotechnology Co., Ltd.
L-ZO488-5mg
1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine
 74389-69-8 >99%
5mg
 ￥2971.0 2022-03-01
SHANG HAI XIAN DING Biotechnology Co., Ltd.
L-ZO488-1mg
1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine
 74389-69-8 >99%
1mg
 ￥1018.0 2022-03-01
abcr
AB478496-25 mg
1-O-Octadecyl-2-O-acetyl-sn-glycero-3-phosphocholine
 74389-69-8
25mg
 €219.80 2021-09-16
abcr
AB478496-100 mg
1-O-Octadecyl-2-O-acetyl-sn-glycero-3-phosphocholine
 74389-69-8
100MG
 €542.20 2021-09-16
SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd.
O19520-25mg
1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine
 74389-69-8
25mg
 ￥8568.0 2021-09-08
SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd.
O19520-5mg
1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine
 74389-69-8
5mg
 ￥2358.0 2021-09-08
WU HAN AN JIE KAI Biomedical Technology Co., Ltd.
ajci73324-1mg
PAF C-18
 74389-69-8 98%
1mg
 ￥423.00 2022-04-26

1-O-Octadecyl-2-O-acetyl-sn-glycero-3-phosphocholine Production Method

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