Cas no 742-20-1 (Cyclopenthiazide)

Cyclopenthiazide is a thiazide diuretic primarily used in the management of hypertension and edema associated with congestive heart failure, renal dysfunction, or hepatic cirrhosis. Its mechanism of action involves inhibiting the sodium-chloride symporter in the distal convoluted tubule, promoting natriuresis and diuresis. Key advantages include its predictable pharmacokinetics, moderate potency, and compatibility with combination therapies for enhanced antihypertensive effects. Cyclopenthiazide also exhibits a favorable safety profile when administered at appropriate doses, with monitoring for electrolyte imbalances. Its long half-life allows for once-daily dosing, improving patient adherence. The compound is well-studied, with established efficacy in reducing blood pressure and fluid retention in clinical settings.

Cyclopenthiazide structure

Product Name:Cyclopenthiazide

CAS No:742-20-1

MF:C₁₃H₁₈ClN₃O₄S₂

MW:379.882719516754

CID:39741

PubChem ID:2904

Update Time:2025-07-20

Cyclopenthiazide Chemical and Physical Properties

Names and Identifiers

- Cyclopenthiazide
- 6-Chloro-3-(cyclopentylmethyl)-1,1-dioxo-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide
- 6-chloro-3-(cyclopentylmethyl)-1,1-dioxo-3,4-dihydro-2H-1λ<sup>6</sup>,2,4-benzothiadiazine-7-sulfonamide
- SCHEMBL49142
- CHEBI:91686
- 96783-05-0
- DB13532
- 866GEV195O
- 8341-Su
- Ciba 8341-Su
- 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(cyclopentylmethyl)-3,4-dihydro-, 1,1-dioxide, (-)-
- 3-Cyclopentylmethylhydrochlorothiazide
- Benesal
- Tsiklometiazid
- 2H-1,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(cyclopentylmethyl)-3,4-dihydro-, 1,1-dioxide
- 3-Cyclopentylmethyl hydrochlorothiazide deriv
- 2H-1,2,4-Benzothiadiazine-7-sulfonamide,6-chloro-3-(cyclopentylmethyl)-3,4-dihydro-, 1,1-dioxide
- BRD-A41250306-001-03-4
- VX4S2N85F5
- 1-METHYL-1H-BENZIMIDAZOLE-2-THIOL95
- SR-01000776288-2
- HMS3715G09
- BKYKPTRYDKTTJY-UHFFFAOYSA-N
- Tox21_110481_1
- Navidrex K
- CAS-742-20-1
- SU 8341
- 96783-06-1
- E78748
- BRN 0630346
- Navidrix
- 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(cyclopentylmethyl)-3,4-dihydro-, 1,1-dioxide, (+)-
- Q3676519
- BPBio1_001197
- CYCLOPENTHIAZIDE [USAN]
- W-104425
- UNII-866GEV195O
- UNII-T7817XC41U
- SMR000528497
- Navidrex
- 2H-1,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(cyclopentylmethyl)-3,4-dihydro-,1,1-dioxide
- NCGC00016534-01
- 6-chloro-3-(cyclopentylmethyl)-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide
- Su-8341
- 6-chloro-3-(cyclopentylmethyl)-1,1-dioxo-3,4-dihydro-2H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide
- Prestwick1_000994
- (+)-Cyclopenthiazide
- CYCLOPENTHIAZIDE [JAN]
- Cyclopenthiazide, (-)-
- Ciclopentiazida [INN-Spanish]
- BS-48942
- DTXCID802868
- Tsiklometiazid (cyclomethiazide)
- Cyclopenthiazide, (+)-
- SU 8341Cyclomethiazide
- CCG-220994
- 6-Chloro-3-(cyclopentylmethyl)-3,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
- HY-109542
- T7817XC41U
- Cyclopentiazid
- EINECS 212-012-5
- Cyclopenthiazide,(S)
- Cyclometiazid
- Prestwick3_000994
- CYCLOPENTHIAZIDE [INN]
- EN300-18562604
- Cyclopenthiazide [USAN:INN:BAN:JAN]
- MLS000737270
- HMS2886L05
- Ciclopentiazida
- D02061
- Salimed
- Navidreks
- AKOS024462515
- Cyclopenthiazidum [INN-Latin]
- NCGC00179312-03
- 742-20-1
- Salimid
- CYCLOPENTHIAZIDE [WHO-DD]
- Navidrex (TN)
- HMS1571G09
- 6-Chloro-3-cyclopentylmethyl-7-sulfamoyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-Dioxide
- GTPL7899
- WLN: T66 BSWM EM DHJ HG ISZW D1- AL5TJ
- SPBio_002978
- 6-chloro-3-(cyclopentylmethyl)-1,1-diketo-3,4-dihydro-2H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide
- (-)-Cyclopenthiazide
- BCP24493
- 6-Chloro-3-(cyclopentylmethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
- 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-(cyclopentylmethyl)-3,4-dihydro-, 1,1-dioxide
- Ultra-Minzil
- Prestwick2_000994
- Salurilo-C
- CYCLOPENTHIAZIDE [MART.]
- 6-Chloro-3-(cyclopentylmethyl)-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide
- NSC107679
- DTXSID4022868
- AB00513990
- CYCLOPENTHIAZIDE [MI]
- SR-01000776288
- Cyclomethiazide
- NSC 107679
- Ciclopentiazide
- HMS2098G09
- NS00006210
- Ciclopentiazide [DCIT]
- UNII-VX4S2N85F5
- CHEMBL1373254
- Cyclopenthiazide (JAN/USAN/INN)
- CS-0031283
- Cyclopenthiazidum
- Tox21_110481
- Prestwick0_000994
- BSPBio_001087
- NSC-107679
- FT-0665381
- DA-72482
- BRD-A41250306-001-11-7
- 6-chloro-3-(cyclopentylmethyl)-1,1-diketo-3,4-dihydro-2H-1$l^(6),2,4-benzothiadiazine-7-sulfonamide
- 212-012-5
- MFCD00865825
- Cyclopenthiazide (Standard)
- 6-chloro-3-(cyclopentylmethyl)-1,1-dioxo-3,4-dihydro-2H-benzo(e)(1,2,4)thiadiazine-7-sulfonamide
- Cyclopenthiazidum (INN-Latin)
- C03AA07
- CYCLOPENTHIAZIDE (MART.)
- Ciclopentiazida (INN-Spanish)
- HY-109542R
- Inchi： 1S/C13H18ClN3O4S2/c14-9-6-10-12(7-11(9)22(15,18)19)23(20,21)17-13(16-10)5-8-3-1-2-4-8/h6-8,13,16-17H,1-5H2,(H2,15,18,19)
- InChI Key： BKYKPTRYDKTTJY-UHFFFAOYSA-N
- SMILES： ClC1C(=CC2=C(C=1)NC(CC1CCCC1)NS2(=O)=O)S(N)(=O)=O

Computed Properties

Exact Mass: 379.04300
Monoisotopic Mass: 379.0427261g/mol
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 3
Hydrogen Bond Acceptor Count: 7
Heavy Atom Count: 23
Rotatable Bond Count: 3
Complexity: 637
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 1
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Surface Charge: 0
Tautomer Count: nothing
XLogP3: nothing
Topological Polar Surface Area: 135?2

Experimental Properties

Color/Form: crystal
Density: 1.3650 (rough estimate)
Melting Point: 230°
Boiling Point: 605.6 °C at 760 mmHg
Flash Point: 320.1 °C
Refractive Index: 1.6100 (estimate)
PSA: 135.12000
LogP: 4.92630

Cyclopenthiazide Security Information

Toxicity：LD50 in rats, mice (mg/kg): 141.8 ±24, 232.4 ±25 i.v. (Barrett)

Cyclopenthiazide Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
TRC	C988420-25mg	Cyclopenthiazide	742-20-1		25mg	$ 227.00	2023-09-08
TRC	C988420-250mg	Cyclopenthiazide	742-20-1		250mg	$ 1777.00	2023-09-08
XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd.	BP098	Cyclopenthiazide	742-20-1	British Pharmacopoeia (BP) Reference Standard		￥2447.79	2022-02-22
WU HAN AN JIE KAI Biomedical Technology Co., Ltd.	ajci18078-100mg	Cyclopenthiazide	742-20-1	98%	100mg	￥466.00	2023-09-09
WU HAN AN JIE KAI Biomedical Technology Co., Ltd.	ajci18078-500mg	Cyclopenthiazide	742-20-1	98%	500mg	￥819.00	2023-09-09
A2B Chem LLC	AW53913-5g	2H-1,2,4-Benzothiadiazine-7-sulfonamide,6-chloro-3-(cyclopentylmethyl)-3,4-dihydro-, 1,1-dioxide	742-20-1	98%	5g	$255.00	2024-04-19
XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd.	BP098-100mg	Cyclopenthiazide	742-20-1		100mg	￥1958.23	2024-12-26
Aaron	AR01CBZ9-10g	2H-1,2,4-Benzothiadiazine-7-sulfonamide,6-chloro-3-(cyclopentylmethyl)-3,4-dihydro-, 1,1-dioxide	742-20-1	98%	10g	$467.00	2025-02-09
A2B Chem LLC	AW53913-250mg	2H-1,2,4-Benzothiadiazine-7-sulfonamide,6-chloro-3-(cyclopentylmethyl)-3,4-dihydro-, 1,1-dioxide	742-20-1	98%	250mg	$22.00	2024-04-19
A2B Chem LLC	AW53913-1g	2H-1,2,4-Benzothiadiazine-7-sulfonamide,6-chloro-3-(cyclopentylmethyl)-3,4-dihydro-, 1,1-dioxide	742-20-1	98%	1g	$55.00	2024-04-19

Cyclopenthiazide Suppliers

Tiancheng Chemical (Jiangsu) Co., Ltd

Gold Member

Audited Supplier

(CAS:742-20-1)環(huán)戊甲噻嗪

Order Number:LE1879541;LE12340

Stock Status:in Stock

Quantity:25KG,200KG,1000KG

Purity:99%

Pricing Information Last Updated:Friday, 20 June 2025 12:37

Price ($):discuss personally

Email:[email protected]

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