Cas no 73937-25-4 (4,6-Dimethylpyrimidine-2-carboxamide)

4,6-Dimethylpyrimidine-2-carboxamide is a heterocyclic organic compound featuring a pyrimidine core substituted with methyl groups at the 4 and 6 positions and a carboxamide functional group at the 2 position. This structure imparts unique reactivity and stability, making it a valuable intermediate in pharmaceutical and agrochemical synthesis. Its well-defined molecular framework allows for precise modifications, facilitating the development of targeted bioactive molecules. The compound exhibits favorable solubility in common organic solvents, enhancing its utility in synthetic applications. Its high purity and consistent performance make it a reliable choice for research and industrial processes requiring controlled functionalization of pyrimidine derivatives.
4,6-Dimethylpyrimidine-2-carboxamide structure
73937-25-4 structure
Product Name:4,6-Dimethylpyrimidine-2-carboxamide
CAS No:73937-25-4
MF:C7H9N3O
MW:151.165860891342
CID:554963
PubChem ID:12562157
Update Time:2025-11-02

4,6-Dimethylpyrimidine-2-carboxamide Chemical and Physical Properties

Names and Identifiers

    • 4,6-Dimethylpyrimidine-2-carboxamide
    • 2-Pyrimidinecarboxamide,4,6-dimethyl-(6CI,9CI)
    • SB55865
    • SCHEMBL2469053
    • 2-Pyrimidinecarboxamide, 4,6-dimethyl-
    • 4,6-dimethylpyrimidine carboxamide
    • AKOS022186818
    • 73937-25-4
    • DTXSID40879111
    • Inchi: 1S/C7H9N3O/c1-4-3-5(2)10-7(9-4)6(8)11/h3H,1-2H3,(H2,8,11)
    • InChI Key: GQSYNOBFTDVBDM-UHFFFAOYSA-N
    • SMILES: O=C(C1=NC(C)=CC(C)=N1)N

Computed Properties

  • Exact Mass: 151.074561919g/mol
  • Monoisotopic Mass: 151.074561919g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 1
  • Complexity: 150
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 0.2
  • Topological Polar Surface Area: 68.9?2

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Additional information on 4,6-Dimethylpyrimidine-2-carboxamide

4,6-Dimethylpyrimidine-2-carboxamide (CAS No. 73937-25-4): Properties, Applications, and Market Insights

4,6-Dimethylpyrimidine-2-carboxamide (CAS No. 73937-25-4) is a specialized organic compound belonging to the pyrimidine family. This heterocyclic compound has garnered significant attention in recent years due to its versatile applications in pharmaceuticals, agrochemicals, and material science. With the increasing demand for pyrimidine derivatives in drug discovery and sustainable agriculture, understanding the properties and potential of this compound is crucial for researchers and industry professionals.

The molecular structure of 4,6-Dimethylpyrimidine-2-carboxamide features a pyrimidine ring substituted with two methyl groups at positions 4 and 6, along with a carboxamide functional group at position 2. This unique arrangement contributes to its chemical stability and reactivity, making it an important building block in organic synthesis. Recent studies have shown growing interest in dimethylpyrimidine derivatives for their potential biological activities, particularly in antimicrobial and anti-inflammatory applications.

In pharmaceutical research, 4,6-Dimethylpyrimidine-2-carboxamide serves as a key intermediate in the synthesis of various drug candidates. The compound's structural features make it valuable for developing small molecule therapeutics, especially in areas like kinase inhibitors and enzyme modulators. With the global pharmaceutical market increasingly focusing on targeted therapies, this compound has become more relevant in drug discovery pipelines.

The agrochemical industry has also shown interest in 4,6-Dimethylpyrimidine-2-carboxamide and related compounds. As sustainable agriculture practices gain momentum worldwide, researchers are exploring pyrimidine-based agrochemicals as potential alternatives to traditional pesticides. The compound's structural properties may contribute to the development of novel plant protection agents with improved environmental profiles.

From a synthetic chemistry perspective, 4,6-Dimethylpyrimidine-2-carboxamide offers several advantages. Its relatively simple structure allows for various modifications, enabling the creation of diverse chemical libraries. This characteristic aligns well with current trends in combinatorial chemistry and high-throughput screening methods used in modern drug discovery programs.

The global market for pyrimidine derivatives has been steadily growing, with 4,6-Dimethylpyrimidine-2-carboxamide occupying a niche but important segment. Market analysts project increased demand for such specialized intermediates, particularly in regions with strong pharmaceutical and agrochemical manufacturing bases. The compound's commercial availability and relatively straightforward synthesis make it accessible to both academic researchers and industrial applications.

Recent advancements in analytical techniques have enabled more detailed studies of 4,6-Dimethylpyrimidine-2-carboxamide's physical and chemical properties. Researchers have characterized its solubility profile, thermal stability, and spectroscopic features, providing valuable data for formulation scientists and process chemists. These developments contribute to better understanding of the compound's behavior in various applications.

Environmental considerations have become increasingly important in chemical research, and 4,6-Dimethylpyrimidine-2-carboxamide has been subject to various biodegradation and ecotoxicity studies. Current research suggests that this compound exhibits favorable environmental profiles compared to some traditional chemical intermediates, making it potentially attractive for green chemistry applications.

The future outlook for 4,6-Dimethylpyrimidine-2-carboxamide appears promising, particularly in light of emerging trends in personalized medicine and precision agriculture. As researchers continue to explore the compound's potential applications, we may see expanded uses in areas such as materials science, where pyrimidine-based compounds are being investigated for electronic and optical applications.

Quality control and standardization of 4,6-Dimethylpyrimidine-2-carboxamide remain important considerations for industrial applications. Manufacturers and suppliers have developed rigorous analytical methods to ensure consistent purity and quality, addressing the needs of demanding applications in pharmaceutical and agrochemical production.

For researchers working with 4,6-Dimethylpyrimidine-2-carboxamide, proper handling and storage recommendations should be followed to maintain compound integrity. While not classified as hazardous under normal conditions, standard laboratory safety protocols should be observed when working with this chemical intermediate.

The scientific literature contains numerous references to 4,6-Dimethylpyrimidine-2-carboxamide and related compounds, reflecting the ongoing interest in this chemical class. Recent publications have explored novel synthetic routes, structural modifications, and potential biological activities, contributing to a growing body of knowledge about this versatile intermediate.

As the chemical industry continues to evolve, compounds like 4,6-Dimethylpyrimidine-2-carboxamide will likely play increasingly important roles in addressing global challenges in healthcare, food production, and sustainable development. Its combination of structural simplicity and functional versatility makes it a valuable tool for researchers across multiple disciplines.

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