Cas no 72141-44-7 (4-Chloro-2-methoxypyridine)
4-Chloro-2-methoxypyridine is a versatile heterocyclic compound featuring a chloro substituent at the 4-position and a methoxy group at the 2-position of the pyridine ring. This structure imparts reactivity suitable for various synthetic applications, particularly in pharmaceutical and agrochemical intermediates. The electron-withdrawing chloro group enhances electrophilic substitution potential, while the methoxy group contributes to stability and influences regioselectivity in further functionalization. Its high purity and well-defined reactivity profile make it a valuable building block for cross-coupling reactions, nucleophilic substitutions, and other transformations. The compound is typically handled under standard laboratory conditions, with appropriate precautions for halogenated pyridines.
4-Chloro-2-methoxypyridine structure
Product Name:4-Chloro-2-methoxypyridine
CAS No:72141-44-7
MF:C6H6ClNO
MW:143.570940494537
MDL:MFCD06738656
CID:562362
PubChem ID:22638510
Update Time:2025-06-08
4-Chloro-2-methoxypyridine Chemical and Physical Properties
Names and Identifiers
-
- 4-Chloro-2-methoxypyridine
- 2-Methoxy-4-chloro-pyridine
- 4-Chloro-2-methoxy-pyridine
- Pyridine,4-chloro-2-methoxy-
- 2-Methoxy-4-chloropyridine
- 2-Methoxy-4-chlor-pyridin
- 4-Chlor-2-methoxy-pyridin
- GS-5843
- SCHEMBL676002
- J-514960
- FT-0641394
- WTDUQQXDOAPXAQ-UHFFFAOYSA-N
- SY022137
- MFCD06738656
- Z1201623697
- DTXSID30627204
- AC-33371
- 72141-44-7
- AKOS006346551
- AB27571
- CS-W019075
- A9403
- EN300-97314
- AM20061466
- 2-Methoxy-4-chloropyridine; 4-Chloro-2-methoxypyridine
- DB-006176
-
- MDL: MFCD06738656
- Inchi: 1S/C6H6ClNO/c1-9-6-4-5(7)2-3-8-6/h2-4H,1H3
- InChI Key: WTDUQQXDOAPXAQ-UHFFFAOYSA-N
- SMILES: ClC1C=CN=C(C=1)OC
Computed Properties
- Exact Mass: 143.01400
- Monoisotopic Mass: 143.014
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 1
- Heavy Atom Count: 9
- Rotatable Bond Count: 1
- Complexity: 89.1
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 2
- Topological Polar Surface Area: 22.1A^2
Experimental Properties
- Color/Form: White to Yellow Solid
- Density: 1.210
- Melting Point: 26 oC
- Boiling Point: 177 oC
- Flash Point: 61 oC
- Refractive Index: 1.518
- PSA: 22.12000
- LogP: 1.74360
4-Chloro-2-methoxypyridine Security Information
- Signal Word:Warning
- Hazard Statement: H302;H315;H319;H335
- Warning Statement: P261;P305+P351+P338
- Hazard Category Code: 36/37/38
- Safety Instruction: S26; S36/37/39
- Storage Condition:2-8 °C
- Risk Phrases:R36/37/38
4-Chloro-2-methoxypyridine Customs Data
- HS CODE:2933399090
- Customs Data:
China Customs Code:
2933399090Overview:
2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date
Summary:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
4-Chloro-2-methoxypyridine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| AstaTech | 63218-1/G |
4-CHLORO-2-METHOXYPYRIDINE |
72141-44-7 | 97% | 1g |
$10 | 2023-09-16 | |
| AstaTech | 63218-5/G |
4-CHLORO-2-METHOXYPYRIDINE |
72141-44-7 | 97% | 5/G |
$75 | 2022-06-01 | |
| AstaTech | 63218-25/G |
4-CHLORO-2-METHOXYPYRIDINE |
72141-44-7 | 97% | 25/G |
$262 | 2022-06-01 | |
| Alichem | A023023373-25g |
4-Chloro-2-methoxypyridine |
72141-44-7 | 97% | 25g |
$282.13 | 2023-09-01 | |
| Fluorochem | 049150-1g |
4-Chloro-2-methoxypyridine |
72141-44-7 | 95% | 1g |
£18.00 | 2022-03-01 | |
| Fluorochem | 049150-5g |
4-Chloro-2-methoxypyridine |
72141-44-7 | 95% | 5g |
£54.00 | 2022-03-01 | |
| Fluorochem | 049150-10g |
4-Chloro-2-methoxypyridine |
72141-44-7 | 95% | 10g |
£95.00 | 2022-03-01 | |
| Fluorochem | 049150-25g |
4-Chloro-2-methoxypyridine |
72141-44-7 | 95% | 25g |
£193.00 | 2022-03-01 | |
| TRC | C368675-1g |
4-Chloro-2-methoxypyridine |
72141-44-7 | 1g |
$ 64.00 | 2023-09-08 | ||
| TRC | C368675-2.5g |
4-Chloro-2-methoxypyridine |
72141-44-7 | 2.5g |
$ 121.00 | 2023-09-08 |
4-Chloro-2-methoxypyridine Related Literature
-
Shun-Ze Zhan,Mian Li,Xiao-Ping Zhou,Dan Li,Seik Weng Ng RSC Adv., 2011,1, 1457-1459
-
Maomao Hou,Fenglin Zhong,Qiu Jin,Enjiang Liu,Jie Feng,Tengyun Wang,Yue Gao RSC Adv., 2017,7, 34392-34400
-
Jason Wan Lab Chip, 2020,20, 4528-4538
-
Craig A. Kelly,David R. Rosseinsky Phys. Chem. Chem. Phys., 2001,3, 2086-2090
-
Andreas Nenning,Manuel Holzmann,Jürgen Fleig,Alexander K. Opitz Mater. Adv., 2021,2, 5422-5431
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