Cas no 71607-32-4 ((2S,3S)-2,3-Bis((4-methylbenzoyl)oxy)succinic acid hydrate)

(2S,3S)-2,3-Bis((4-methylbenzoyl)oxy)succinic acid hydrate is a chiral diester derivative of succinic acid, featuring two para-methylbenzoyl groups esterified at the 2 and 3 positions. Its stereospecific (2S,3S) configuration ensures high enantiomeric purity, making it valuable for asymmetric synthesis and pharmaceutical applications. The hydrate form enhances stability and handling. This compound serves as a versatile intermediate in organic synthesis, particularly for constructing complex chiral molecules. Its rigid structure and functional groups allow for selective reactivity, useful in fine chemical and catalyst development. The presence of aromatic esters contributes to its solubility in organic solvents, facilitating its use in controlled reactions.
(2S,3S)-2,3-Bis((4-methylbenzoyl)oxy)succinic acid hydrate structure
71607-32-4 structure
Product Name:(2S,3S)-2,3-Bis((4-methylbenzoyl)oxy)succinic acid hydrate
CAS No:71607-32-4
MF:C20H20O9
MW:404.367406845093
MDL:MFCD00151034
CID:59237
PubChem ID:12297760
Update Time:2025-10-05

(2S,3S)-2,3-Bis((4-methylbenzoyl)oxy)succinic acid hydrate Chemical and Physical Properties

Names and Identifiers

    • (2S,3S)-2,3-Bis((4-methylbenzoyl)oxy)succinic acid hydrate
    • Di-p-toluoyl-L-tartaric acid monohydrate
    • (2R,3R)-2,3-Bis((4-methylbenzoyl)oxy)succinic acid hydrate
    • DI-P-TOLUOYL-D-TARTARIC ACID MONOHYDRATE
    • Di-p-toluoyl-L-tartaric acid
    • Butanedioicacid, 2,3-bis[(4-methylbenzoyl)oxy]-, monohydrate, (2R,3R)- (9CI)
    • Butanedioicacid, 2,3-bis[(4-methylbenzoyl)oxy]-, monohydrate, [R-(R*,R*)]-
    • C20H20O9
    • AM81408
    • Di-p-toluoyl-L-tartaricacidmonohydrate
    • FS-3921
    • CS-0153080
    • MFCD00151034
    • 32634-66-5
    • AKOS016842298
    • W-104517
    • DI-P-TOLUOYL-D-TRATARIC ACID MONOHYDRATE
    • 71607-32-4
    • (2R,3R)-2,3-bis[(4-methylbenzoyl)oxy]butanedioic acid;hydrate
    • AC-3429
    • SCHEMBL3859934
    • (2R,3R)-2,3-bis(4-methylbenzoyloxy)butanedioic acid hydrate
    • MDL: MFCD00151034
    • Inchi: 1S/C20H18O8.H2O/c1-11-3-7-13(8-4-11)19(25)27-15(17(21)22)16(18(23)24)28-20(26)14-9-5-12(2)6-10-14;/h3-10,15-16H,1-2H3,(H,21,22)(H,23,24);1H2/t15-,16-;/m1./s1
    • InChI Key: FOTRUJUPLHRVNU-QNBGGDODSA-N
    • SMILES: O(C(C1C=CC(C)=CC=1)=O)[C@@H](C(=O)O)[C@H](C(=O)O)OC(C1C=CC(C)=CC=1)=O.O

Computed Properties

  • Exact Mass: 404.11100
  • Monoisotopic Mass: 404.111
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 3
  • Hydrogen Bond Acceptor Count: 9
  • Heavy Atom Count: 29
  • Rotatable Bond Count: 9
  • Complexity: 533
  • Covalently-Bonded Unit Count: 2
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 2
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 128A^2

Experimental Properties

  • Color/Form: White or off white crystalline powder
  • Melting Point: 163-165 oC
  • Boiling Point: 686 °C at 760 mmHg
  • Flash Point: 368.7 °C
  • PSA: 136.43000
  • LogP: 2.15930
  • Specific Rotation: 140 o (c=1, MeoH)
  • Vapor Pressure: No data available

(2S,3S)-2,3-Bis((4-methylbenzoyl)oxy)succinic acid hydrate Security Information

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(2S,3S)-2,3-Bis((4-methylbenzoyl)oxy)succinic acid hydrate Suppliers

Suzhou Senfeida Chemical Co., Ltd
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(CAS:71607-32-4)Di-p-toluoyl-D-tartaric acid monohydrate
Order Number:sfd11879
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Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:36
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Tiancheng Chemical (Jiangsu) Co., Ltd
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(CAS:71607-32-4)D-(+)-二對甲基苯甲酰酒石酸(一水)
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Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:41
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Additional information on (2S,3S)-2,3-Bis((4-methylbenzoyl)oxy)succinic acid hydrate

Comprehensive Overview of (2S,3S)-2,3-Bis((4-methylbenzoyl)oxy)succinic acid hydrate (CAS No. 71607-32-4)

(2S,3S)-2,3-Bis((4-methylbenzoyl)oxy)succinic acid hydrate is a specialized organic compound with significant applications in pharmaceutical and chemical research. Its unique stereochemistry, marked by the (2S,3S) configuration, and the presence of 4-methylbenzoyl groups, makes it a valuable intermediate in the synthesis of chiral molecules. The compound's CAS No. 71607-32-4 serves as a critical identifier for researchers and regulatory bodies, ensuring precise communication in scientific literature and commercial transactions.

In recent years, the demand for chiral compounds like (2S,3S)-2,3-Bis((4-methylbenzoyl)oxy)succinic acid hydrate has surged due to their role in enantioselective synthesis. This trend aligns with the growing focus on green chemistry and sustainable pharmaceutical manufacturing, where minimizing waste and optimizing reaction efficiency are paramount. Researchers often search for "chiral building blocks" or "stereoselective synthesis" to find compounds like this, highlighting its relevance in modern organic chemistry.

The hydrate form of this compound adds another layer of utility, as it often improves solubility and stability—key factors in formulation development. Analytical techniques such as HPLC, NMR, and X-ray crystallography are typically employed to characterize its purity and confirm its stereochemical integrity. These methods are frequently queried in search engines by professionals seeking "how to analyze chiral compounds" or "techniques for verifying stereochemistry."

Beyond its synthetic applications, (2S,3S)-2,3-Bis((4-methylbenzoyl)oxy)succinic acid hydrate has garnered attention in drug discovery due to its potential as a scaffold for bioactive molecules. Its structural features, including the succinic acid core, are compatible with prodrug design, a hot topic in medicinal chemistry. Searches for "prodrug strategies" or "biodegradable linkers" often intersect with discussions about such compounds.

From a commercial perspective, suppliers and manufacturers emphasize the compound's high purity and batch consistency, addressing concerns raised in queries like "reliable sources for research chemicals." Regulatory compliance, particularly with REACH and GMP standards, is another critical aspect frequently searched by procurement specialists.

In summary, (2S,3S)-2,3-Bis((4-methylbenzoyl)oxy)succinic acid hydrate (CAS No. 71607-32-4) exemplifies the intersection of advanced organic synthesis and practical applications in pharmaceuticals. Its role in chiral technology, combined with its adaptability to sustainable chemistry principles, ensures its continued relevance in both academic and industrial settings.

Recommended suppliers
Suzhou Senfeida Chemical Co., Ltd
(CAS:71607-32-4)Di-p-toluoyl-D-tartaric acid monohydrate
sfd11879
Purity:99.9%
Quantity:200kg
Price ($):Inquiry
Email
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:71607-32-4)D-(+)-二對甲基苯甲酰酒石酸(一水)
LE2581592
Purity:99%
Quantity:25KG,200KG,1000KG
Price ($):Inquiry
Email