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  Jonas Kind,Lukas Kaltschnee,Martin Leyendecker,Christina M. Thiele Chem. Commun., 2016,52, 12506-12509
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  Christopher J. Harrison,Kyle J. Berean,Enrico Della Gaspera,Jian Zhen Ou,Richard B. Kaner,Kourosh Kalantar-zadeh,Torben Daeneke Nanoscale, 2016,8, 16276-16283
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• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Diarylethers
• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Ethers Diarylethers
• Solvents and Organic Chemicals Organic Compounds Amines/Sulfonamides

4-(2-Naphthalenyloxy)benzenamine: A Comprehensive Overview

4-(2-Naphthalenyloxy)benzenamine, also known by its CAS number 71311-83-6, is a compound of significant interest in various fields of chemistry and materials science. This compound is characterized by its unique structure, which combines a naphthalene ring with a phenol group and an amine functionality. The presence of these functional groups imparts versatile chemical properties, making it a valuable molecule for both academic research and industrial applications.

The synthesis of 4-(2-Naphthalenyloxy)benzenamine typically involves multi-step organic reactions, often starting from naphthalene derivatives. Recent advancements in synthetic methodologies have focused on improving the yield and purity of this compound, leveraging catalytic systems and green chemistry principles. For instance, researchers have explored the use of transition metal catalysts to facilitate coupling reactions, thereby streamlining the synthesis process.

In terms of applications, 4-(2-Naphthalenyloxy)benzenamine has found utility in the development of advanced materials, particularly in the realm of conductive polymers. Its aromatic structure and electron-rich amine group make it an ideal candidate for doping agents in polymer electronics. Recent studies have demonstrated its potential in enhancing the electrical conductivity of polyaniline-based materials, which are widely used in flexible electronics and energy storage devices.

Beyond materials science, this compound has also shown promise in pharmaceutical research. The naphthalene moiety is known for its bioactivity, and the amine group can serve as a site for further functionalization to create drug-like molecules. For example, researchers have investigated its role as a precursor for designing anti-inflammatory agents and antioxidants. These findings underscore its versatility as a building block in medicinal chemistry.

The toxicological profile of 4-(2-Naphthalenyloxy)benzenamine has been a subject of recent scrutiny. Studies indicate that while it exhibits moderate cytotoxicity in vitro, its systemic toxicity is relatively low when administered at therapeutic doses. This information is crucial for its safe handling and application in industrial settings.

In conclusion, 4-(2-Naphthalenyloxy)benzenamine (CAS No: 71311-83-6) stands out as a multifaceted compound with diverse applications across chemistry and materials science. Its unique structure and functional groups continue to inspire innovative research directions, particularly in the development of advanced materials and pharmaceutical agents. As our understanding of this compound deepens, it is poised to play an even more significant role in shaping future technologies.

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