Cas no 705927-35-1 (1-Methyl-1H-indazol-7-ol)

1-Methyl-1H-indazol-7-ol is a heterocyclic organic compound featuring an indazole core substituted with a methyl group at the 1-position and a hydroxyl group at the 7-position. This structure imparts unique reactivity and potential utility in pharmaceutical and agrochemical applications. The presence of the hydroxyl group enhances its ability to participate in hydrogen bonding and derivatization reactions, making it a versatile intermediate for synthesizing more complex molecules. Its stable indazole scaffold is advantageous for developing bioactive compounds, particularly in medicinal chemistry, where such frameworks are often explored for their pharmacological properties. The compound is typically handled under standard laboratory conditions, requiring protection from light and moisture to maintain stability.
1-Methyl-1H-indazol-7-ol structure
1-Methyl-1H-indazol-7-ol structure
Product Name:1-Methyl-1H-indazol-7-ol
CAS No:705927-35-1
MF:C8H8N2O
MW:148.16192150116
MDL:MFCD12028570
CID:557474
PubChem ID:20391322
Update Time:2025-06-14

1-Methyl-1H-indazol-7-ol Chemical and Physical Properties

Names and Identifiers

    • 1H-Indazol-7-ol,1-methyl-
    • 1-METHYL-1H-INDAZOL-7-OL
    • 1-methylindazol-7-ol
    • 7-Hydroxy-1-methyl-1H-indazole
    • AG-C-09014
    • CTK8A0180
    • MolPort-004-764-753
    • SureCN2272282
    • CS-0208947
    • J-504875
    • DTXSID70606598
    • 705927-35-1
    • AB92305
    • MFCD12028570
    • AKOS006317462
    • SCHEMBL2272282
    • 1-Methyl-1H-indazol-7-ol
    • MDL: MFCD12028570
    • Inchi: 1S/C8H8N2O/c1-10-8-6(5-9-10)3-2-4-7(8)11/h2-5,11H,1H3
    • InChI Key: ZSRWUUAXXXQENT-UHFFFAOYSA-N
    • SMILES: OC1=CC=CC2C=NN(C)C=21

Computed Properties

  • Exact Mass: 148.063662883g/mol
  • Monoisotopic Mass: 148.063662883g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 0
  • Complexity: 151
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.2
  • Topological Polar Surface Area: 38?2

1-Methyl-1H-indazol-7-ol Pricemore >>

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Additional information on 1-Methyl-1H-indazol-7-ol

Comprehensive Overview of 1-Methyl-1H-indazol-7-ol (CAS No. 705927-35-1): Properties, Applications, and Research Insights

1-Methyl-1H-indazol-7-ol (CAS No. 705927-35-1) is a heterocyclic organic compound that has garnered significant attention in pharmaceutical and biochemical research due to its unique structural features and potential applications. This compound belongs to the indazole family, a class of nitrogen-containing bicyclic structures known for their diverse biological activities. The presence of a methyl group at the 1-position and a hydroxyl group at the 7-position makes this molecule particularly interesting for drug discovery and material science applications.

In recent years, researchers have focused on the synthesis and optimization of 1-Methyl-1H-indazol-7-ol derivatives, driven by the growing demand for novel therapeutic agents. The compound's scaffold is frequently explored in the development of kinase inhibitors, which are crucial in targeting cancer and inflammatory diseases. Its structural versatility allows for modifications that can enhance bioavailability and binding affinity, making it a valuable intermediate in medicinal chemistry.

The rise of computational chemistry and AI-driven drug design has further amplified interest in 705927-35-1. Scientists are leveraging machine learning algorithms to predict the compound's interactions with biological targets, accelerating the discovery of next-generation drugs. This aligns with the broader trend of green chemistry, where researchers aim to reduce synthetic steps and improve yields using sustainable methods.

From a commercial perspective, 1-Methyl-1H-indazol-7-ol is often sought after by pharmaceutical manufacturers and research institutions. Its CAS number (705927-35-1) serves as a critical identifier in global chemical databases, ensuring precise tracking and regulatory compliance. Suppliers and distributors emphasize high-purity grades (>98%) to meet the stringent requirements of preclinical studies and API development.

Beyond therapeutics, this compound has potential applications in agrochemicals and material science. Its aromatic system and functional groups make it a candidate for designing fluorescent probes or polymeric materials with tailored properties. Researchers are also investigating its role in catalysis, where it could serve as a ligand in transition-metal complexes.

For those searching "buy 1-Methyl-1H-indazol-7-ol" or "705927-35-1 supplier," it's essential to verify certificates of analysis (CoA) and ensure compliance with regional regulations. The compound's stability under various storage conditions (typically 2–8°C in inert atmospheres) is another frequently asked topic among buyers.

In summary, 1-Methyl-1H-indazol-7-ol (CAS No. 705927-35-1) represents a versatile building block in modern chemistry. Its integration into drug discovery pipelines and material innovation underscores its importance, while advancements in synthetic methodologies continue to unlock new possibilities. As research progresses, this compound is poised to remain a focal point in interdisciplinary scientific endeavors.

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