Cas no 680859-99-8 (1,2-Dimethyl-1H-pyrrolo[3,2-c]pyridine)

1,2-Dimethyl-1H-pyrrolo[3,2-c]pyridine is a heterocyclic organic compound featuring a fused pyrrole-pyridine core structure with methyl substituents at the 1- and 2-positions. This scaffold is of interest in medicinal chemistry and materials science due to its electron-rich aromatic system, which enables applications in ligand design and optoelectronic materials. The dimethyl substitution enhances stability and modulates electronic properties, making it a versatile intermediate for synthesizing pharmacologically active compounds or functional materials. Its rigid, planar structure also facilitates π-stacking interactions, useful in supramolecular chemistry. The compound is typically handled under inert conditions due to potential sensitivity to oxidation.
1,2-Dimethyl-1H-pyrrolo[3,2-c]pyridine structure
680859-99-8 structure
Product Name:1,2-Dimethyl-1H-pyrrolo[3,2-c]pyridine
CAS No:680859-99-8
MF:C9H10N2
MW:146.189101696014
CID:968751
PubChem ID:20817285
Update Time:2025-10-12

1,2-Dimethyl-1H-pyrrolo[3,2-c]pyridine Chemical and Physical Properties

Names and Identifiers

    • 1,2-Dimethyl-1H-pyrrolo[3,2-c]pyridine
    • 1,2-dimethylpyrrolo[3,2-c]pyridine
    • 1h-pyrrolo[3,2-c]pyridine,1,2-dimethyl-
    • 680859-99-8
    • AKOS006329557
    • SCHEMBL10151401
    • A867134
    • DTXSID10609922
    • DB-354156
    • MDL: MFCD09263782
    • Inchi: 1S/C9H10N2/c1-7-5-8-6-10-4-3-9(8)11(7)2/h3-6H,1-2H3
    • InChI Key: JNZZRIPJDDRDAF-UHFFFAOYSA-N
    • SMILES: N1(C)C(C)=CC2C=NC=CC1=2

Computed Properties

  • Exact Mass: 146.08400
  • Monoisotopic Mass: 146.084398327g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 0
  • Complexity: 147
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.3
  • Topological Polar Surface Area: 17.8?2

Experimental Properties

  • PSA: 17.82000
  • LogP: 1.88170

1,2-Dimethyl-1H-pyrrolo[3,2-c]pyridine Customs Data

  • HS CODE:2933990090
  • Customs Data:

    China Customs Code:

    2933990090

    Overview:

    2933990090. Other heterocyclic compounds containing only nitrogen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Additional information on 1,2-Dimethyl-1H-pyrrolo[3,2-c]pyridine

1,2-Dimethyl-1H-pyrrolo[3,2-c]pyridine: A Comprehensive Overview

1,2-Dimethyl-1H-pyrrolo[3,2-c]pyridine (CAS No. 680859-99-8) is a heterocyclic aromatic compound with a unique structural arrangement that combines pyrrole and pyridine moieties. This compound has garnered significant attention in the fields of organic chemistry, materials science, and pharmacology due to its versatile properties and potential applications. The pyrrolopyridine core of this molecule is particularly interesting, as it exhibits a range of electronic and optical characteristics that make it suitable for various advanced applications.

The synthesis of 1,2-Dimethyl-1H-pyrrolo[3,2-c]pyridine involves a multi-step process that typically begins with the preparation of precursor compounds. Recent advancements in synthetic methodologies have enabled chemists to achieve higher yields and better purity levels. For instance, researchers have employed microwave-assisted synthesis techniques to streamline the reaction process, significantly reducing the time required for compound formation. This approach not only enhances efficiency but also minimizes the environmental impact of the synthesis procedure.

One of the most notable features of 1,2-Dimethyl-1H-pyrrolo[3,2-c]pyridine is its electronic structure. The conjugated system within the molecule allows for efficient electron delocalization, which contributes to its high stability and reactivity. This property has made it a valuable component in the development of advanced materials such as organic light-emitting diodes (OLEDs) and photovoltaic devices. Recent studies have demonstrated that incorporating this compound into OLED architectures can lead to improved device performance, including higher luminous efficiency and longer operational lifetimes.

In the realm of pharmacology, 1,2-Dimethyl-1H-pyrrolo[3,2-c]pyridine has shown promise as a lead compound for drug discovery. Its ability to interact with various biological targets makes it a candidate for therapeutic applications in areas such as cancer treatment and neurodegenerative diseases. For example, researchers have explored its potential as an inhibitor of kinase enzymes, which are often overexpressed in cancer cells. Preliminary results indicate that this compound exhibits selective binding affinity for certain kinase isoforms, suggesting its potential as a targeted therapy.

The optical properties of 1,2-Dimethyl-1H-pyrrolo[3,2-c]pyridine have also been leveraged in the development of sensors and diagnostic tools. Its ability to fluoresce under specific conditions makes it an ideal candidate for use in biosensing applications. Recent studies have highlighted its utility in detecting metal ions and small organic molecules with high sensitivity and specificity. This capability could pave the way for innovative diagnostic platforms that are both cost-effective and highly accurate.

From a materials science perspective, 1,2-Dimethyl-1H-pyrrolo[3,2-c]pyridine has been investigated for its role in creating novel organic semiconductors. The compound's ability to form stable charge transfer complexes has been exploited in the design of advanced electronic materials. Researchers have reported enhanced carrier mobility in thin-film transistor devices incorporating this compound, suggesting its potential for use in flexible electronics and wearable technologies.

In conclusion, 1,2-Dimethyl-1H-pyrrolo[3,2-c]pyridine (CAS No. 680859-99-8) is a multifaceted compound with a wide range of applications across diverse scientific disciplines. Its unique structural features and electronic properties continue to drive innovative research efforts aimed at unlocking its full potential. As advancements in synthetic methods and materials science progress further, this compound is poised to play an increasingly important role in shaping future technologies and therapeutic interventions.

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