Cas no 66992-27-6 (N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt)

N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt is a zwitterionic biological buffer widely used in biochemical and molecular biology applications. Its key advantages include excellent pH stability in the physiological range (pH 6.5–8.5), high water solubility, and minimal interference with enzymatic reactions. The compound exhibits low metal ion binding capacity, making it suitable for metal-sensitive systems. Its hydroxyl groups enhance solubility in aqueous solutions while maintaining low membrane permeability, reducing cellular toxicity. This buffer is particularly useful in electrophoresis, cell culture, and protein purification due to its consistent buffering capacity and compatibility with biological systems. The sodium salt form ensures improved solubility and ease of use in various experimental conditions.
N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt structure
66992-27-6 structure
Product Name:N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt
CAS No:66992-27-6
MF:C6H14NNaO5S
MW:235.233831882477
MDL:MFCD00067425
CID:58526
PubChem ID:24891416
Update Time:2025-05-20

N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt Chemical and Physical Properties

Names and Identifiers

    • N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt
    • BES sodium salt
    • 2-[N,N-Bis(2-hydroxyethyl)amino]ethanesulfonic acid sodium salt
    • Sodium 2-[bis(2-hydroxyethyl)amino]ethanesulfonate
    • BES-Na
    • N. Sodium N-di (2-hydroxyethyl) -2-aminoethanesulfonate
    • MDL: MFCD00067425
    • Inchi: 1S/C6H15NO5S.Na/c8-4-1-7(2-5-9)3-6-13(10,11)12;/h8-9H,1-6H2,(H,10,11,12);/q;+1/p-1
    • InChI Key: CFQLQLSIZOWFNV-UHFFFAOYSA-M
    • SMILES: S(CCN(CCO)CCO)(=O)(=O)[O-].[Na+]

Computed Properties

  • Exact Mass: 235.04900
  • Monoisotopic Mass: 235.049
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 6
  • Heavy Atom Count: 14
  • Rotatable Bond Count: 7
  • Complexity: 209
  • Covalently-Bonded Unit Count: 2
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 109A^2

Experimental Properties

  • Solubility: H2O: 0.35?g/mL, clear, colorless
  • PSA: 109.28000
  • LogP: -1.10100
  • pka: 7.1 (Free acid)(at 25℃)

N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt Security Information

  • Hazardous Material transportation number:NONH for all modes of transport
  • WGK Germany:3
  • Hazard Category Code: 10-15
  • Safety Instruction: S22-S24/25
  • Hazardous Material Identification: F Xn
  • Storage Condition:Store in cold storage.
  • Safety Term:S22;S24/25
  • Risk Phrases:R; R10; R15; R

N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt Customs Data

  • HS CODE:2922199090
  • Customs Data:

    China Customs Code:

    2922199090

    Overview:

    2922199090. Other amino alcohols and their ethers,Esters and their salts(Except those containing more than one oxygen-containing group). VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to, The color of ethanolamine and its salt should be reported, The package of ethanolamine and its salt shall be declared

    Summary:

    2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Alichem
A450001282-500g
Sodium 2-(bis(2-hydroxyethyl)amino)ethanesulfonate
66992-27-6 97%
500g
$212.00 2023-09-01
HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI
SB8238-100g
N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt
66992-27-6 ≥99%
100g
¥320元 2023-09-15
HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI
SB8238-25g
N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt
66992-27-6 ≥99%
25g
¥100元 2023-09-15
HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI
SB8238-500g
N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt
66992-27-6 ≥99%
500g
¥1290元 2023-09-15
HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI
SB8238-5g
N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt
66992-27-6 ≥99%
5g
¥30元 2023-09-15
HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI
SB2891-100g
N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt
66992-27-6 ≥99%
100g
¥1220元 2023-09-15
HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI
SB2891-25g
N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt
66992-27-6 ≥99%
25g
¥365元 2023-09-15
HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI
SB2891-5g
N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt
66992-27-6 ≥99%
5g
¥100元 2023-09-15
SHANG HAI YI EN HUA XUE JI SHU Co., Ltd.
R015840-100g
N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt
66992-27-6 RG 98%
100g
¥239 2023-09-08
SHANG HAI YI EN HUA XUE JI SHU Co., Ltd.
R015840-25g
N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt
66992-27-6 RG 98%
25g
¥65 2023-09-08

N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt Suppliers

Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:66992-27-6)2-(二乙醇胺基)乙磺酸鈉
Order Number:LE26331401;LE9717
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:55
Price ($):discuss personally
Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:66992-27-6)N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt
Order Number:A942263
Stock Status:in Stock
Quantity:500g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 15:42
Price ($):178.0

N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt Related Literature

Related Categories

Additional information on N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt

Comprehensive Guide to N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt (CAS No. 66992-27-6)

N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt (CAS No. 66992-27-6) is a highly versatile organic compound widely used in biochemical and pharmaceutical research. This zwitterionic buffer is known for its excellent buffering capacity in the physiological pH range, making it a preferred choice in cell culture media, diagnostic assays, and protein stabilization. Its unique structure, featuring both hydroxyethyl and sulfonic acid groups, ensures high solubility and stability in aqueous solutions.

The growing demand for biocompatible buffers in life sciences has put N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt in the spotlight. Researchers frequently search for "best buffers for cell culture" or "stable pH regulators in diagnostics," and this compound fits these applications perfectly. Its low toxicity and compatibility with biological systems make it ideal for in vitro studies, aligning with the increasing focus on green chemistry and sustainable lab practices.

One of the key advantages of N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt is its minimal interference with enzymatic reactions, a feature highly valued in PCR and ELISA applications. Recent trends in personalized medicine and biopharmaceutical development have further driven its adoption, as precise pH control is critical for reproducible results. Additionally, its role in cryopreservation solutions has gained attention, especially with the rise of cell therapy research.

From an industrial perspective, 66992-27-6 is increasingly used in cosmetic formulations due to its mildness and skin-friendly properties. Searches like "gentle buffering agents for skincare" highlight this trend. The compound’s ability to maintain pH stability in formulations containing active ingredients like vitamins and peptides makes it a valuable additive in anti-aging and sensitive skin products.

In summary, N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt (CAS No. 66992-27-6) is a multifaceted compound with applications spanning biomedical research, diagnostics, and cosmetics. Its compatibility with modern scientific and industrial needs ensures its continued relevance in high-growth sectors. For researchers and manufacturers seeking reliable, non-toxic buffers, this compound remains a top contender.

Recommended suppliers
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:66992-27-6)2-(二乙醇胺基)乙磺酸鈉
LE26331401;LE9717
Purity:99%/99%
Quantity:25KG,200KG,1000KG/25KG,200KG,1000KG
Price ($):Inquiry/Inquiry
Email
Amadis Chemical Company Limited
(CAS:66992-27-6)N,N-Bis(2-hydroxyethyl)-2-aminoethanesulfonic acid sodium salt
A942263
Purity:99%
Quantity:500g
Price ($):178.0
Email