Production Method 1

27372-03-8

66729-02-0

84567-98-6

Reaction Conditions

1.1 Reagents: Potassium hydroxide Solvents: Methanol ,  Water ;  16 h, rt
1.2 Reagents: Hydrochloric acid Solvents: Water ;  acidified

Reference

Mechanistic Studies of Fatty Acid Activation by CYP152 Peroxygenases Reveal Unexpected Desaturase Activity

Pickl, Mathias; et al, ACS Catalysis, 2019, 9(1), 565-577

Production Method 2

609-14-3

66729-02-0

84567-98-6

Reaction Conditions

1.1 Reagents: Sodium borohydride Solvents: Ethanol ,  Water ;  0 °C; 0 °C → rt; 3 h, rt
1.2 Reagents: Potassium hydroxide Solvents: Methanol ,  Water ;  16 h, rt
1.3 Reagents: Hydrochloric acid Solvents: Water ;  acidified

Reference

Mechanistic Studies of Fatty Acid Activation by CYP152 Peroxygenases Reveal Unexpected Desaturase Activity

Pickl, Mathias; et al, ACS Catalysis, 2019, 9(1), 565-577

(2R,3S)-3-hydroxy-2-methyl-butanoic acid Raw materials

• 3-Hydroxy-2-methylbutanoic Acid Ethyl Ester(Mixture of Diastereomers)
• ethyl 2-methyl-3-oxobutanoate

(2R,3S)-3-hydroxy-2-methyl-butanoic acid Preparation Products

• (2S,3S)-3-Hydroxy-2-methylbutanoic Acid (84567-98-6)
• (2R,3S)-3-hydroxy-2-methyl-butanoic acid (66729-02-0)

• 1. Evolution of important glucosinolates in three common Brassica vegetables during their processing into vegetable powder and in vitro gastric digestion
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• 3. Evolution of hierarchical porous structures in supramolecular guest–host hydrogels?
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• 4. Fe/Fe3C@C nanoparticles encapsulated in N-doped graphene–CNTs framework as an efficient bifunctional oxygen electrocatalyst for robust rechargeable Zn–air batteries?
  Zhiyan Chen,Nan Wu,Yaobing Wang,Bing Wang,Yingde Wang J. Mater. Chem. A, 2018,6, 516-526
• 5. Establishing empirical design rules of nucleic acid templates for the synthesis of silver nanoclusters with tunable photoluminescence and functionalities towards targeted bioimaging applications?
  Jason Y. C. Lim,Yong Yu,Guorui Jin,Kai Li,Yi Lu,Jianping Xie Nanoscale Adv., 2020,2, 3921-3932

• Solvents and Organic Chemicals Organic Compounds Lipids and lipid-like molecules Fatty Acyls Hydroxy fatty acids
• Solvents and Organic Chemicals Organic Compounds Lipids and lipid-like molecules Fatty Acyls Fatty acids and conjugates Hydroxy fatty acids

• 72604-79-6((R)-2-(Hydroxymethyl)butanoic acid)
• 58888-84-9(3-Hydroxy Valproic Acid (Mixture of Diastereomers))
• 17502-28-2(rac-(1R,2S)-2-hydroxycyclopentane-1-carboxylic acid, cis)
• 609-69-8(2-hydroxycyclohexane-1-carboxylic acid)
• 5980-21-2(3-Hydroxy-4-methylpentanoic Acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)