Cas no 66657-42-9 (2-Oxo-1,2,3,4-tetrahydroquinoline-6-sulfonyl chloride)

2-Oxo-1,2,3,4-tetrahydroquinoline-6-sulfonyl chloride is a versatile sulfonyl chloride derivative used as a key intermediate in organic synthesis and pharmaceutical applications. Its reactive sulfonyl chloride group enables efficient derivatization, making it valuable for constructing sulfonamides, sulfonate esters, and other functionalized compounds. The tetrahydroquinoline scaffold provides a rigid framework, enhancing selectivity in medicinal chemistry and agrochemical research. This compound is particularly useful in the development of bioactive molecules due to its compatibility with nucleophilic substitution reactions. High purity and stability under controlled conditions ensure reliable performance in synthetic workflows. Its structural features make it a preferred choice for researchers seeking to modify sulfonamide-based pharmacophores.
2-Oxo-1,2,3,4-tetrahydroquinoline-6-sulfonyl chloride structure
66657-42-9 structure
Product Name:2-Oxo-1,2,3,4-tetrahydroquinoline-6-sulfonyl chloride
CAS No:66657-42-9
MF:C9H8ClNO3S
MW:245.682720184326
MDL:MFCD06655638
CID:837978
PubChem ID:4962209
Update Time:2025-06-07

2-Oxo-1,2,3,4-tetrahydroquinoline-6-sulfonyl chloride Chemical and Physical Properties

Names and Identifiers

    • 2-Oxo-1,2,3,4-tetrahydroquinoline-6-sulfonyl chloride
    • 2-oxo-1,2,3,4-tetrahydro-6-quinolinesulfonyl chloride(SALTDATA: FREE)
    • 1,2,3,4-tetrahydro-2-oxo-6-Quinolinesulfonyl chloride
    • 2-OXO-1,2,3,4-TETRAHYDRO-QUINOLINE-6-SULFONYL CHLORIDE
    • 2-oxo-1,2,3,4-tetrahydroquinolin-6-ylsulphonyl chloride
    • 6-(chlorosulfonyl)-1,3,4-trihydroquinolin-2-one
    • 6-chlorosulfonyl-2-oxo-1,2,3,4-tetrahydroquinoline
    • AC1NLQA9
    • PubChem5681
    • SBB011873
    • BB 0256749
    • FT-0678004
    • MFCD06655638
    • EN300-13073
    • SCHEMBL2586707
    • 2-Oxo-1,2,3,4-tetrahydro-6-quinolinesulfonylchloride
    • 2-oxo-1,2,3,4-tetrahydroquinoline-6-sulfonylchloride
    • 2-oxo-1,2,3,4-tetrahydro-6-quinolinesulfonyl chloride
    • F2184-0199
    • 6-Quinolinesulfonoyl chloride, 1,2,3,4-tetrahydro-2-oxo-
    • AKOS000200829
    • BS-13991
    • 66657-42-9
    • DTXSID20407032
    • 2-oxo-3,4-dihydro-1H-quinoline-6-sulfonyl chloride
    • 2-oxo-1,2,3,4-tetrahydro-quinoline-6-sulfonyl chloride, AldrichCPR
    • 6-Quinolinesulfonyl chloride, 1,2,3,4-tetrahydro-2-oxo-
    • CS-WAA0239
    • DB-073783
    • MDL： MFCD06655638
    • Inchi： 1S/C9H8ClNO3S/c10-15(13,14)7-2-3-8-6(5-7)1-4-9(12)11-8/h2-3,5H,1,4H2,(H,11,12)
    • InChI Key： ICRHXBNAKSHNRD-UHFFFAOYSA-N
    • SMILES： ClS(C1C=CC2=C(C=1)CCC(N2)=O)(=O)=O

Computed Properties

  • Exact Mass: 244.99144
  • Monoisotopic Mass: 244.9913420g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 1
  • Complexity: 362
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.1
  • Topological Polar Surface Area: 71.6?2

Experimental Properties

  • Density: 1.484±0.06 g/cm3 (20 oC 760 Torr),
  • Melting Point: 209-212 oC (dec.)
  • Boiling Point: 455.8°C at 760 mmHg
  • Flash Point: 229.5°C
  • Refractive Index: 1.592
  • Solubility: Slightly soluble (1.6 g/l) (25 o C),
  • PSA: 63.24

2-Oxo-1,2,3,4-tetrahydroquinoline-6-sulfonyl chloride Security Information

  • HazardClass：IRRITANT

2-Oxo-1,2,3,4-tetrahydroquinoline-6-sulfonyl chloride Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Alichem
A189006637-1g
2-Oxo-1,2,3,4-tetrahydroquinoline-6-sulfonyl chloride
 66657-42-9 95%
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Alichem
A189006637-5g
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Chemenu
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TRC
O870645-100mg
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O870645-250mg
2-Oxo-1,2,3,4-tetrahydroquinoline-6-sulfonyl Chloride
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O870645-500mg
2-Oxo-1,2,3,4-tetrahydroquinoline-6-sulfonyl Chloride
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TRC
O870645-1g
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 $ 485.00 2022-06-03
TRC
O870645-2.5g
2-Oxo-1,2,3,4-tetrahydroquinoline-6-sulfonyl Chloride
 66657-42-9
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 $1028.00 2023-05-17
TRC
O870645-5g
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SHANG HAI XIAN DING Biotechnology Co., Ltd.
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 66657-42-9 98+%
50mg
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