Hydroquinolones
Hydroquinolones are a class of chemical compounds that possess both hydroxyl and quinoline functional groups. They exhibit a broad spectrum of applications, including pharmaceuticals, agrochemicals, and dyes. In the pharmaceutical industry, hydroquinolones are primarily used as intermediates in the synthesis of various drug molecules due to their unique structural features. For instance, these compounds can serve as precursors for the production of antifungal, antibacterial, and antiviral drugs. Their quinoline core provides excellent bioavailability and pharmacological activity, making them valuable tools for medicinal chemistry research. In agrochemical applications, hydroquinolones are often employed in herbicides and fungicides, where their ability to disrupt cell membranes or inhibit enzyme activities leads to effective pest control. Additionally, some derivatives of hydroquinolones find use as dyes owing to their color stability and light-fastness properties. The versatility and multifunctionality of these compounds make them indispensable in multiple sectors of the chemical industry.
| Structure | Chemical Name | CAS | MF |
|---|---|---|---|
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4(1H)-Quinolinone, 2,3-dihydro-6,7-dimethoxy-2-methyl- | 57012-79-0 | C12H15NO3 |
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Quinoline-2,4(1H,3H)-dione | 52851-41-9 | C9H7NO2 |
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4(1H)-Quinolinone, 1-methyl-2-undecyl- | 59443-02-6 | C21H31NO |
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4-Quinolinol, 2-pentyl- | 62869-70-9 | C14H17NO |
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2-Quinolinecarboxylicacid, 1,4-dihydro-7-methoxy-4-oxo-, methyl ester | 77474-23-8 | C12H11NO4 |
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Furo[2,3-b]quinolinium,2,3-dihydro-2-(1-hydroxy-1-methylethyl)-4,7,8-trimethoxy-9-methyl-, (2S)- | 79808-98-3 | C18H24NO5 |
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ethyl 4-hydroxy-2-methylquinoline-3-carboxylate | 73987-39-0 | C13H13NO3 |
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4-Quinolinol, 3-(3-chloro-2-butenyl)-2-methyl- | 88654-98-2 | C14H14ClNO |
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2(1H)-Quinolinone,3,4,8-trimethyl- | 30016-06-9 | C12H13NO |
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Ethanone,2,2,2-trifluoro-1-(1(2H)-quinolinyl)- | 30831-85-7 | C11H8F3NO |
Related Literature
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Aloke Das,K. K. Mahato,Chayan K. Nandi,Tapas Chakraborty,Shridhar R. Gadre,Nikhil A. Gokhale Phys. Chem. Chem. Phys., 2002,4, 2162-2168
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Gloria Belén Ramírez-Rodríguez,José Manuel Delgado-López,Jaime Gómez-Morales CrystEngComm, 2013,15, 2206-2212
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Brindha J.,Balamurali M. M.,Kaushik Chanda RSC Adv., 2019,9, 34720-34734
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Long Deng,Qian Zou,Biao Liu,Wenhui Ye,Chengfei Zhuo,Li Chen,Ze-Yuan Deng,Ya-Wei Fan,Jing Li Food Funct., 2018,9, 4234-4245
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Eric Besson,Stéphane Gastaldi,Emily Bloch,Selma Aslan,Hakim Karoui,Olivier Ouari,Micael Hardy Analyst, 2019,144, 4194-4203
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