Cas no 66493-42-3 (H-Gly-Gly-pNA·HCl)
H-Gly-Gly-pNA·HCl is a synthetic peptide substrate commonly used in enzymatic assays, particularly for studying protease activity. The compound consists of a glycyl-glycine sequence linked to p-nitroaniline (pNA), with hydrochloric acid as a counterion. Upon cleavage by proteases, the release of pNA can be quantified spectrophotometrically at 405 nm, providing a reliable measure of enzymatic kinetics. Its high purity and stability make it suitable for precise biochemical research. The inclusion of HCl ensures solubility in aqueous buffers, facilitating consistent experimental conditions. This substrate is valued for its specificity and sensitivity in detecting endopeptidase or aminopeptidase activity in both research and diagnostic applications.
H-Gly-Gly-pNA·HCl structure
Product Name:H-Gly-Gly-pNA·HCl
CAS No:66493-42-3
MF:C10H13ClN4O4
MW:288.68762087822
CID:2098332
PubChem ID:131676726
Update Time:2025-05-28
H-Gly-Gly-pNA·HCl Chemical and Physical Properties
Names and Identifiers
-
- H-Gly-Gly-pNA · HCl
- diglycyl-p-nitroanilide
- H-Gly-Gly-pNA.HCl
- FG110796
- 2-amino-N-[2-(4-nitroanilino)-2-oxoethyl]acetamide;hydrochloride
- H-Gly-Gly-pNA HCl
- 66493-42-3
- H-Gly-Gly-pNA·HCl
-
- Inchi： 1S/C10H12N4O4.ClH/c11-5-9(15)12-6-10(16)13-7-1-3-8(4-2-7)14(17)18;/h1-4H,5-6,11H2,(H,12,15)(H,13,16);1H
- InChI Key： CKLOAMFWKWPQOR-UHFFFAOYSA-N
- SMILES： Cl.O=C(CNC(CN)=O)NC1C=CC(=CC=1)[N+](=O)[O-]
Computed Properties
- Exact Mass: 288.0625326Da
- Monoisotopic Mass: 288.0625326Da
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 4
- Hydrogen Bond Acceptor Count: 5
- Heavy Atom Count: 19
- Rotatable Bond Count: 4
- Complexity: 320
- Covalently-Bonded Unit Count: 2
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 130?2
H-Gly-Gly-pNA·HCl Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | H254055-50mg |
H-Gly-Gly-pNA·HCl |
66493-42-3 | 50mg |
$ 290.00 | 2022-06-04 | ||
| TRC | H254055-100mg |
H-Gly-Gly-pNA·HCl |
66493-42-3 | 100mg |
$ 475.00 | 2022-06-04 | ||
| TRC | H254055-250mg |
H-Gly-Gly-pNA·HCl |
66493-42-3 | 250mg |
$ 950.00 | 2022-06-04 |
H-Gly-Gly-pNA·HCl Related Literature
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Joseph H. Bisesi,Tara Sabo-Attwood Environ. Sci.: Nano, 2014,1, 574-583
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Vishwesh Venkatraman,Marco Foscato,Vidar R. Jensen,Bj?rn K?re Alsberg J. Mater. Chem. A, 2015,3, 9851-9860
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Ana G. Neo,Ana Bornadiego,Jesús Díaz,Stefano Marcaccini,Carlos F. Marcos Org. Biomol. Chem., 2013,11, 6546-6555
-
Guiying Zhang,Maosheng Cheng,Yanni Li,Keliang Liu,Lifeng Cai Chem. Commun., 2013,49, 11086-11088
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