Cas no 65259-91-8 (1-(4-Isopropylphenyl)-2-thiourea)

1-(4-Isopropylphenyl)-2-thiourea is a thiourea derivative characterized by the presence of an isopropylphenyl substituent. This compound is of interest in organic synthesis and coordination chemistry due to its ability to act as a ligand, forming stable complexes with transition metals. The isopropyl group enhances its lipophilicity, potentially improving solubility in nonpolar solvents. Its thiourea moiety provides strong chelating properties, making it useful in catalytic applications and metal ion extraction processes. The compound may also serve as an intermediate in pharmaceutical or agrochemical research. Careful handling is advised due to the potential reactivity of the thiourea functional group under certain conditions.
1-(4-Isopropylphenyl)-2-thiourea structure
65259-91-8 structure
Product Name:1-(4-Isopropylphenyl)-2-thiourea
CAS No:65259-91-8
MF:C10H14N2S
MW:194.296560764313
MDL:MFCD00060459
CID:502020
PubChem ID:2759509
Update Time:2025-10-05

1-(4-Isopropylphenyl)-2-thiourea Chemical and Physical Properties

Names and Identifiers

    • Thiourea,N-[4-(1-methylethyl)phenyl]-
    • 1-(4-Isopropylphenyl)-2-thiourea
    • (4-propan-2-ylphenyl)thiourea
    • 1-(4-Isopropylphenyl)thiourea
    • N-(4-isopropylphenyl)thiourea
    • FT-0641004
    • 65259-91-8
    • [4-(propan-2-yl)phenyl]thiourea
    • N-[4-(Propan-2-yl)phenyl]thiourea
    • SCHEMBL5523228
    • AKOS000369706
    • EN300-28857
    • A835040
    • CS-0116702
    • DTXSID20374811
    • 1-(4-propan-2-ylphenyl)thiourea
    • MFCD00060459
    • MDL: MFCD00060459
    • Inchi: 1S/C10H14N2S/c1-7(2)8-3-5-9(6-4-8)12-10(11)13/h3-7H,1-2H3,(H3,11,12,13)
    • InChI Key: HYJQJTWSGAJMDV-UHFFFAOYSA-N
    • SMILES: S=C(N)NC1C=CC(=CC=1)C(C)C

Computed Properties

  • Exact Mass: 194.08800
  • Monoisotopic Mass: 194.088
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 3
  • Complexity: 172
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.9
  • Topological Polar Surface Area: 70.1A^2

Experimental Properties

  • Density: 1.159
  • Melting Point: 139-141°C
  • Boiling Point: 298.4 °C at 760 mmHg
  • Flash Point: 134.3 °C
  • Refractive Index: 1.646
  • PSA: 70.14000
  • LogP: 3.23880

1-(4-Isopropylphenyl)-2-thiourea Security Information

1-(4-Isopropylphenyl)-2-thiourea Customs Data

  • HS CODE:2930909090
  • Customs Data:

    China Customs Code:

    2930909090

    Overview:

    2930909090. Other organic sulfur compounds. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

1-(4-Isopropylphenyl)-2-thiourea Pricemore >>

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Additional information on 1-(4-Isopropylphenyl)-2-thiourea

Recent Advances in the Study of 1-(4-Isopropylphenyl)-2-thiourea (CAS: 65259-91-8)

1-(4-Isopropylphenyl)-2-thiourea (CAS: 65259-91-8) is a thiourea derivative that has garnered significant attention in recent years due to its potential applications in chemical biology and pharmaceutical research. This compound, characterized by its unique structural features, has been investigated for its role in various biochemical processes, including enzyme inhibition and molecular recognition. The latest research highlights its promising utility in drug discovery and development, particularly in targeting specific enzymes and pathways involved in disease mechanisms.

Recent studies have focused on the synthesis and optimization of 1-(4-Isopropylphenyl)-2-thiourea to enhance its biological activity and selectivity. Advanced computational modeling and high-throughput screening techniques have been employed to elucidate its binding affinity and interaction with target proteins. These efforts have revealed that the compound exhibits potent inhibitory effects against certain kinases and proteases, making it a candidate for further investigation in therapeutic applications.

In addition to its biochemical properties, 1-(4-Isopropylphenyl)-2-thiourea has been explored for its potential in material science. Its ability to form stable complexes with metal ions has opened new avenues for the development of sensors and catalysts. Researchers have also investigated its role in supramolecular chemistry, where it serves as a building block for designing functional materials with tailored properties.

The safety and pharmacokinetic profile of 1-(4-Isopropylphenyl)-2-thiourea have been subjects of recent preclinical studies. Preliminary data suggest that the compound has a favorable toxicity profile, with minimal off-target effects. However, further in vivo studies are required to fully assess its therapeutic potential and optimize its delivery mechanisms. These findings underscore the importance of continued research to translate these discoveries into clinical applications.

In conclusion, 1-(4-Isopropylphenyl)-2-thiourea (CAS: 65259-91-8) represents a versatile compound with broad implications in chemical biology and pharmaceutical research. Its unique properties and promising preliminary results warrant further investigation to unlock its full potential. Future studies should focus on refining its synthesis, expanding its applications, and addressing any challenges related to its development as a therapeutic agent or functional material.

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