Cas no 175205-18-2 ((4-propylphenyl)thiourea)

(4-Propylphenyl)thiourea is a thiourea derivative characterized by the presence of a propylphenyl substituent. This compound is of interest in organic synthesis and coordination chemistry due to its ability to act as a ligand, forming stable complexes with transition metals. The propyl group enhances lipophilicity, potentially improving solubility in nonpolar solvents. Its thiourea moiety offers strong hydrogen-bonding capabilities, making it useful in molecular recognition and self-assembly applications. The compound may also serve as a precursor in the synthesis of heterocycles or as a building block for more complex architectures. Careful handling is advised due to the potential reactivity of the thiourea functional group.
(4-propylphenyl)thiourea structure
(4-propylphenyl)thiourea structure
Product Name:(4-propylphenyl)thiourea
CAS No:175205-18-2
MF:C10H14N2S
MW:194.296560764313
MDL:MFCD00052484
CID:133925
PubChem ID:2795397
Update Time:2025-06-27

(4-propylphenyl)thiourea Chemical and Physical Properties

Names and Identifiers

    • Thiourea,N-(4-propylphenyl)-
    • (4-propylphenyl)thiourea
    • N-(4-PROPYLPHENYL)THIOUREA
    • 4-propylphenylthiourea
    • 4-N-PROPYLPHENYLTHIOUREA
    • 1-(4-N-PROPYLPHENYL)THIOUREA
    • CS-0355856
    • 1-(4-propylphenyl)thiourea
    • FT-0629240
    • Thiourea, N-(4-propylphenyl)-
    • DTXSID10383654
    • AKOS009140789
    • 175205-18-2
    • EN300-87387
    • Maybridge1_007227
    • HMS562A11
    • A811932
    • MDL: MFCD00052484
    • Inchi: 1S/C10H14N2S/c1-2-3-8-4-6-9(7-5-8)12-10(11)13/h4-7H,2-3H2,1H3,(H3,11,12,13)
    • InChI Key: CCWKBXNBOGLFHK-UHFFFAOYSA-N
    • SMILES: S=C(N)NC1C=CC(=CC=1)CCC

Computed Properties

  • Exact Mass: 194.08800
  • Monoisotopic Mass: 194.088
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 13
  • Rotatable Bond Count: 3
  • Complexity: 162
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.8
  • Topological Polar Surface Area: 70.1?2

Experimental Properties

  • Density: 1.164
  • Melting Point: 165℃
  • Boiling Point: 310°C at 760 mmHg
  • Flash Point: 141.3°C
  • Refractive Index: 1.65
  • PSA: 70.14000
  • LogP: 3.06790

(4-propylphenyl)thiourea Security Information

  • Safety Instruction: S37/39
  • Hazardous Material Identification: Xn
  • Safety Term:S37/39
  • Risk Phrases:R20/21/22

(4-propylphenyl)thiourea Customs Data

  • HS CODE:2930909090
  • Customs Data:

    China Customs Code:

    2930909090

    Overview:

    2930909090. Other organic sulfur compounds. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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Additional information on (4-propylphenyl)thiourea

Introduction to (4-propylphenyl)thiourea and Its Applications in Modern Chemical Research

Compound with the CAS number 175205-18-2, known as (4-propylphenyl)thiourea, is a significant molecule in the field of chemical and pharmaceutical research. This compound has garnered considerable attention due to its unique structural properties and potential applications in various scientific domains. The introduction of this compound will delve into its chemical characteristics, synthesis methods, and recent advancements in its utilization across different sectors.

The molecular structure of (4-propylphenyl)thiourea consists of a thiourea core attached to a propyl-substituted phenyl ring. This configuration imparts distinct reactivity and interaction capabilities, making it a valuable candidate for studying molecular interactions and developing novel chemical entities. The presence of both sulfur and nitrogen atoms in its structure allows for diverse functionalization, which is pivotal in medicinal chemistry and material science.

In recent years, the compound has been extensively studied for its role in the development of agrochemicals and pharmaceuticals. Its derivatives have shown promise in inhibiting certain enzymatic pathways, which is crucial for creating effective therapeutic agents. For instance, modifications of the thiourea moiety have led to compounds with enhanced bioactivity against specific targets, highlighting the importance of (4-propylphenyl)thiourea as a scaffold for drug discovery.

The synthesis of (4-propylphenyl)thiourea typically involves the reaction between 4-propylaniline and carbonyl sulfide under controlled conditions. This process requires precise control of temperature and pH to ensure high yield and purity. Advances in synthetic methodologies have enabled more efficient production methods, allowing researchers to explore its applications without significant limitations.

One of the most intriguing aspects of (4-propylphenyl)thiourea is its potential in catalysis. Its ability to act as a ligand or intermediate in various chemical reactions has been exploited in developing novel catalysts for organic transformations. These catalysts are essential for synthesizing complex molecules with high selectivity and efficiency, which are critical in both academic research and industrial applications.

The compound's role in material science is equally noteworthy. Researchers have investigated its properties as a component in conductive polymers and organic semiconductors. The sulfur-rich structure of (4-propylphenyl)thiourea contributes to its ability to enhance the electronic properties of materials, making it a promising candidate for next-generation electronic devices.

Recent studies have also explored the biological activity of derivatives of (4-propylphenyl)thiourea. These derivatives have shown potential as antimicrobial agents, offering new avenues for combating resistant bacterial strains. The thiourea moiety's ability to interact with biological targets makes it an attractive scaffold for designing molecules with therapeutic effects.

The environmental impact of using (4-propylphenyl)thiourea has also been a focus of research. Efforts have been made to develop greener synthetic routes that minimize waste and energy consumption. Such sustainable practices are essential for ensuring that the compound's benefits can be harnessed without compromising environmental integrity.

In conclusion, the multifaceted applications of CAS number 175205-18-2, specifically (4-propylphenyl)thiourea, underscore its importance in modern chemical research. From pharmaceuticals to materials science, this compound continues to inspire innovation and discovery. As research progresses, it is expected that new applications will emerge, further solidifying its role as a cornerstone molecule in various scientific disciplines.

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