Cas no 644-78-0 (2-Hydroxychalcone)

2-Hydroxychalcone is a chalcone derivative characterized by the presence of a hydroxyl group at the 2-position of the aromatic ring. This structural feature enhances its reactivity and utility in organic synthesis, particularly as an intermediate in the preparation of flavonoids and other heterocyclic compounds. Its α,β-unsaturated carbonyl system allows for diverse chemical transformations, including cyclizations and Michael additions. The compound exhibits potential as a ligand in coordination chemistry due to its chelating properties. Additionally, 2-hydroxychalcone has been studied for its biological activities, including antioxidant and anti-inflammatory effects, making it relevant in pharmaceutical research. Its well-defined structure and synthetic versatility make it valuable for both academic and industrial applications.

2-Hydroxychalcone structure

Product Name:2-Hydroxychalcone

CAS No:644-78-0

MF:C₁₅H₁₂O₂

MW:224.254584312439

MDL:MFCD00016449

CID:82901

PubChem ID:87570662

Update Time:2025-10-28

2-Hydroxychalcone Chemical and Physical Properties

Names and Identifiers

- 2-Hydroxychalcone
- (2-Hydroxybenzylidene)acetophenone~3-(2-Hydroxyphenyl)-1-phenyl-2-propen-1-one
- 2-(2-Hydroxybenzal)Acetophenone
- 3-(2-hydroxyphenyl)-1-phenylprop-2-en-1-one
- HYDROXYCHALCONE, 2-(AS)
- (2E)-3-(2-hydroxyphenyl)-1-phenylprop-2-en-1-one
- (E)-1-phenyl-3-(2-hydroxyphenyl)-2-propen-1-one
- (E)-3-(2-hydroxyphenyl)-1-phenyl-2-propen-1-one
- (E)-3-(2-hydroxyphenyl)-1-phenylprop-2-en-1-one
- 2-(2-HYDROXYBENZYLIDENE)ACETOPHENONE
- 2-HYDROXYBENZYLIDENE ACETOPHENONE
- BENZYLIDENE-2-HYDROXYAC
- HYDROXYCHALCONE, 2-
- o-Hydroxychalcone
- SALICYLALACETOPHENONE
- trans-3-(o-hydroxyphenyl)-1-phenyl-2-propen-1-one
- 2-Propen-1-one, 3-(2-hydroxyphenyl)-1-phenyl-
- MLS002608038
- NSC640539
- 3-(2-hydroxyphenyl)-1-phenyl-2-propen-1-one
- (E)-3-(2-hydroxyphenyl)-1-phenyl-prop-2-en-1-one
- Chalcone, 1
- hyd
- 2-Hydroxychalcone, 95%
- CS-0078796
- NSC37432
- CHEMBL147067
- NSC-170281
- HY-119931
- H0234
- (2E)-3-(2-Hydroxyphenyl)-1-phenyl-2-propen-1-one #
- BDBM86002
- AKOS025309995
- SCHEMBL626785
- UDOOPSJCRMKSGL-ZHACJKMWSA-N
- SMR001526790
- AI3-00855
- AKOS000486194
- 6-[(1Z,2Z)-3-Hydroxy-3-phenyl-2-propene-1-ylidene]-2,4-cyclohexadiene-1-one
- MFCD00016449
- SR-01000078236-1
- NSC-640539
- NSC 640539
- (E)-2-Hydroxychalcone
- 42224-53-3
- AB-016/30005051
- 644-78-0
- W-104837
- NS00042209
- NSC170281
- A834764
- HMS3078L22
- CS-0311212
- NSC-37432
- SR-01000078236
- MS-10592
- SCHEMBL626787
- EINECS 211-422-1
- D90823
- STK093271
- MDL： MFCD00016449
- Inchi： 1S/C15H12O2/c16-14-9-5-4-8-13(14)10-11-15(17)12-6-2-1-3-7-12/h1-11,16H/b11-10+
- InChI Key： UDOOPSJCRMKSGL-ZHACJKMWSA-N
- SMILES： OC1C=CC=CC=1/C=C/C(C1C=CC=CC=1)=O
- BRN： 2049134

Computed Properties

Exact Mass: 224.08376
Monoisotopic Mass: 224.083729621g/mol
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 2
Heavy Atom Count: 17
Rotatable Bond Count: 3
Complexity: 277
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Surface Charge: 0
XLogP3: 3.3
Topological Polar Surface Area: 37.3

Experimental Properties

Color/Form: Yellow powder.
Melting Point: 144-150?°C(lit.)
PSA: 37.3
LogP: 3.28830
Solubility: Not determined

2-Hydroxychalcone Security Information

Symbol:
Prompt：warning
Hazard Statement： H315-H319
Warning Statement： P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
WGK Germany：3
Hazard Category Code： 36/37/38
Safety Instruction： 26-36
Hazardous Material Identification：
Risk Phrases：R36/37/38
Safety Term：S26;S36

2-Hydroxychalcone Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd.	H861912-5g	2-Hydroxychalcone	644-78-0	≥98%(GC)(T)	5g	￥448.00	2022-01-10
Fluorochem	003115-1g	2-Hydroxychalcone	644-78-0	98%	1g	￡12.00	2022-02-28
Fluorochem	003115-5g	2-Hydroxychalcone	644-78-0	98%	5g	￡45.00	2022-02-28
Fluorochem	003115-100g	2-Hydroxychalcone	644-78-0	98%	100g	￡116.00	2022-02-28
Fluorochem	003115-250g	2-Hydroxychalcone	644-78-0	98%	250g	￡232.00	2022-02-28
TRC	H604870-50mg	2-Hydroxychalcone	644-78-0		50mg	$ 50.00	2022-06-04
TRC	H604870-100mg	2-Hydroxychalcone	644-78-0		100mg	$ 65.00	2022-06-04
TRC	H604870-500mg	2-Hydroxychalcone	644-78-0		500mg	$ 80.00	2022-06-04
Apollo Scientific	OR8852-1g	2-Hydroxychalcone	644-78-0	98%	1g	￡15.00	2025-02-20
Apollo Scientific	OR8852-5g	2-Hydroxychalcone	644-78-0	98%	5g	￡49.00	2023-04-22

2-Hydroxychalcone Suppliers

Amadis Chemical Company Limited

Gold Member

Audited Supplier

(CAS:644-78-0)2-Hydroxychalcone

Order Number:A834764

Stock Status:in Stock

Quantity:100g

Purity:99%

Pricing Information Last Updated:Friday, 30 August 2024 06:31

Price ($):292.0

Email:[email protected]

Product Official Link

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