- Carboxy mediated stereoselective reduction of ketones with sodium triacetoxyborohydride: synthesis of novel 3,4-fused tetrahydropyran and tetrahydrofuran prolinesLiu, Yi-Tsung; Wong, Jesse K.; Tao, Meng; Osterman, Rebecca; Sannigrahi, Mousumi; et al, Tetrahedron Letters, 2004, 45(32), 6097-6100
Cas no 64187-48-0 (O1-benzyl O2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate)
64187-48-0 structure
Product Name:O1-benzyl O2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
CAS No:64187-48-0
MF:C14H17NO5
MW:279.288484334946
MDL:MFCD00055851
CID:529017
PubChem ID:688411
Update Time:2025-04-19
O1-benzyl O2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate Chemical and Physical Properties
Names and Identifiers
-
- 1,2-Pyrrolidinedicarboxylicacid, 4-hydroxy-, 2-methyl 1-(phenylmethyl) ester, (2S,4R)-
- N-Cbz-L-4-Hydroxyproline methyl ester
- N-Carbobenzoxy-4-trans-hydroxy-L-proline Methyl Ester
- (2S,4R)-1-Benzyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate
- N-(Benzyloxycarbonyl)-4-hydroxyproline Methyl Ester
- Z-hyp-ome
- Z-L-4-hydroxyproline methyl ester
- Z-O-Hyp-OMe
- <i>N<
- N-Benzyloxycarbonyl-4-trans-hydroxy-L-proline Methyl Ester
- N-Cbz-4-trans-hydroxy-L-proline Methyl Ester
- (2S,4R)-1-Benzyloxycarbonyl-4-hydroxypyrrolidin-2-carboxylic acid methyl ester
- (2S,4R)-1-(Benzyloxycarbonyl)-2-(methoxycarbonyl)-4-hydroxypyrrolidine
- O1-benzyl O2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
- 1-Benzyl 2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
- trans-1-benzyloxycarbonyl-4-hydroxy-L-proline methyl ester
- 64187-48-0
- 1-O-benzyl 2-O-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
- (2S,4R)-1-benzyloxycarbonyl-4-hydroxy-2-methoxycarbonylpyrrolidine
- N-benzyloxycarbonyl hydroxyproline methyl ester
- HY-W008370
- VVKAGQHUUDRPOI-NEPJUHHUSA-N
- N-CBZ-TRANS-4-HYDROXY-L-PROLINE METHYL ESTER
- EN300-217064
- (2S,4R)-1-benzyloxycarbonyl-4-hydroxyproline methyl ester
- Z-L-HYP-OME
- C3296
- N-Benzyloxycarbonyl-4-hydroxy-L-trans-proline methyl ester
- N-carbobenzyloxy-trans-4-hydroxy-L-proline, methyl ester
- (2S, 4R)-4-Hydroxy-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester
- (2S,4R)-4-Hydroxy-pyrrolidine-1,2-dicarboxylic acid 1-benzyl ester 2-methyl ester
- N-carbobenzyloxy-trans-4-hydroxy-L-proline methyl ester
- DS-13332
- (2S,4R)-1-benzyloxycarbonyl-2-methoxycarbonyl-4-hydroxypyrrolidine
- CS-W008370
- SCHEMBL636506
- AKOS025117312
- M06127
- 1 -Benzyl 2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
- Methyl(2S,4R)-1-benzyloxycarbonyl-4-hydroxypyrrolidine-2-carboxylate
- FD21779
- MFCD00055851
- BP-12081
-
- MDL： MFCD00055851
- Inchi： 1S/C14H17NO5/c1-19-13(17)12-7-11(16)8-15(12)14(18)20-9-10-5-3-2-4-6-10/h2-6,11-12,16H,7-9H2,1H3/t11-,12+/m1/s1
- InChI Key： VVKAGQHUUDRPOI-NEPJUHHUSA-N
- SMILES： O[C@H]1CN(C(=O)OCC2C=CC=CC=2)[C@H](C(=O)OC)C1
Computed Properties
- Exact Mass: 279.11100
- Monoisotopic Mass: 279.111
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 6
- Heavy Atom Count: 20
- Rotatable Bond Count: 6
- Complexity: 354
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 2
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- XLogP3: 1.1
- Topological Polar Surface Area: 76.1
Experimental Properties
- Color/Form: Liquid
- Density: 1.313
- Boiling Point: 422.8℃ at 760 mmHg
- Flash Point: 209.5±28.7 °C
- Refractive Index: 1.572
- PSA: 76.07000
- LogP: 0.86930
- Solubility: Not determined
- Vapor Pressure: 0.0±1.1 mmHg at 25°C
O1-benzyl O2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate Security Information
- Signal Word：warning
- Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
-
Warning Statement：
P264Thoroughly clean after treatment
P280Wear protective gloves/Wear protective clothing/Wear protective goggles/Wear a protective mask
P305If it enters the eyes
P351Rinse carefully with water for a few minutes
P338Remove the contact lens(If any)And easy to operate,Continue flushing
P337If eye irritation persists
P313Obtain medical advice/care - WGK Germany：3
- Safety Instruction： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Storage Condition：Store at 4°C,-4At ℃Store…Better
O1-benzyl O2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate Customs Data
- HS CODE：2933990090
- Customs Data：
China Customs Code:
2933990090Overview:
2933990090. Other heterocyclic compounds containing only nitrogen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date
Summary:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
O1-benzyl O2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | C3296-1G |
O1-benzyl O2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate |
64187-48-0 | 98.0%(LC&N) | 1G |
￥290.0 | 2022-06-10 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-OJ121-5g |
O1-benzyl O2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate |
64187-48-0 | 97% | 5g |
59.0CNY | 2021-08-05 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-OJ121-25g |
O1-benzyl O2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate |
64187-48-0 | 97+% | 25g |
292CNY | 2021-05-08 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-OJ121-100g |
O1-benzyl O2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate |
64187-48-0 | 97% | 100g |
819.0CNY | 2021-08-05 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-OJ121-20g |
O1-benzyl O2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate |
64187-48-0 | 97% | 20g |
172.0CNY | 2021-08-05 | |
| TRC | B286265-1g |
N-(Benzyloxycarbonyl)-4-hydroxyproline Methyl Ester |
64187-48-0 | 1g |
$ 170.00 | 2022-06-07 | ||
| TRC | B286265-10g |
N-(Benzyloxycarbonyl)-4-hydroxyproline Methyl Ester |
64187-48-0 | 10g |
$ 1360.00 | 2022-06-07 | ||
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R011931-100g |
O1-benzyl O2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate |
64187-48-0 | 97% | 100g |
￥480 | 2024-05-22 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R011931-25g |
O1-benzyl O2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate |
64187-48-0 | 97% | 25g |
￥89 | 2024-05-22 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R011931-5g |
O1-benzyl O2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate |
64187-48-0 | 97% | 5g |
￥28 | 2024-05-22 |
O1-benzyl O2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate Production Method
Production Method 1
Reaction Conditions
1.1 Reagents: Sodium borohydride Solvents: Tetrahydrofuran , Water
Reference
O1-benzyl O2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate Raw materials
O1-benzyl O2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate Preparation Products
O1-benzyl O2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate Suppliers
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier
(CAS:64187-48-0)Z-HYP-OME
Order Number:sfd11431
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:35
Price ($):discuss personally
Email:[email protected]
O1-benzyl O2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate Related Literature
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Eric Besson,Stéphane Gastaldi,Emily Bloch,Selma Aslan,Hakim Karoui,Olivier Ouari,Micael Hardy Analyst, 2019,144, 4194-4203
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Gaurav J. Shah,Eric P.-Y. Chiou,Ming C. Wu,Chang-Jin “CJ” Kim Lab Chip, 2009,9, 1732-1739
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Tao Wang,Yangyang Liu,Yue Deng,Hongbo Fu,Jianmin Chen Environ. Sci.: Nano, 2018,5, 1821-1833
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Hanie Hashtroudi,Ian D. R. Mackinnon J. Mater. Chem. C, 2020,8, 13108-13126
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Hongxia Li,Aikifa Raza,Qiaoyu Ge,Jin-You Lu,TieJun Zhang Soft Matter, 2020,16, 6841-6849
64187-48-0 (O1-benzyl O2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate) Related Products
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Recommended suppliers
Suzhou Senfeida Chemical Co., Ltd
(CAS:64187-48-0)Z-HYP-OME
Purity:99.9%
Quantity:200kg
Price ($):Inquiry