Cas no 633-65-8 (Berberine chloride)
Berberine chloride is a quaternary ammonium salt derived from berberine, an isoquinoline alkaloid found in several medicinal plants. It is widely recognized for its antimicrobial, anti-inflammatory, and hypoglycemic properties. The compound exhibits broad-spectrum activity against bacteria, fungi, and protozoa, making it valuable in pharmaceutical and research applications. Berberine chloride also demonstrates potential in modulating metabolic pathways, particularly in glucose and lipid metabolism. Its high purity and stability ensure reliable performance in laboratory and industrial settings. The product is commonly used in biochemical studies, drug development, and traditional medicine research. Its water solubility and well-documented pharmacological effects further enhance its utility in scientific and therapeutic contexts.
Berberine chloride structure
Product Name:Berberine chloride
CAS No:633-65-8
MF:C20H18ClNO4
MW:371.814224720001
MDL:MFCD00633658
CID:39310
PubChem ID:24891691
Update Time:2025-08-04
Berberine chloride Chemical and Physical Properties
Names and Identifiers
-
- Berberine hydrochloride hydrate
- 5,6-DIHYDRO-9,10-DIMETHOXY-BENZO[G]-1,3-BENZODIOXOLO[5,6-A]QUINOLIZINIUM, CHLORIDE
- BBR
- BERBERINE
- BERBERINE CHLORIDE
- BERBERINE HCL
- BERBERINE HYDROCHLORIDE
- BERBERINE HYDROCHLORIDE N-HYDRATE
- BERBERIN HCL
- CI 75160
- NATURAL YELLOW 18
- NATURAL YELLOW 18 CHLORIDE
- TIMTEC-BB SBB006488
- UMBELLATINE
- 3)benzodioxolo(5,6-a)quinolizinium,5,6-dihydro-9,10-dimethoxy-benzo(g)(c
- 7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-berbiniuchlori
- berberiniumchloride
- BERBERINE CHLORIDE(AHP)
- Berberine chloride form
- Berberine (chloride)
- BERBERINE CHLORIDE(P) (AHP Verified)
- BERBERINE CHLORIDE(P) (AHP Verified) PrintBack
- BERBERINE CHLORIDE(SH) PrintBack
- Berberine Hydrochloride
- 5,6-dihydro-9,10-dimethoxy-1,3-benzodioxolo[5,6-a]benzo[g]quinolizinium chloride (1:1)
- 9,10-dimethoxy-5,6-dihydro[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-7-ium chloride
- Berberinehydrochloride,Berberine chloride form
- BERBERINUMHYDROCHLORIDE
- BerberinehydrochIoride
- Benzodioxide
- Berberinium chloride
- Berberine chloride [JAN]
- Berberin hydrochloride
- UOT4O1BYV8
- MLS002702530
- NSC163088
- AK323614
- DSSTox_CID_4602
- DSSTox_RID_77465
- 9,10-dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,
- NSC-163088
- s2271
- Berberine chloride, primary pharmaceutical reference standard
- B0450
- HY-18258
- MFCD00011939
- CCRIS 8656
- NCGC00257902-01
- Benzo(g)-1,3-benzodioxolo(5,6-a)quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride (1:1)
- 5,6-DIHYDRO-9,10-DIMETHOXYBENZO(G)-1,3-BENZODIOXOLO(5,6-A)QUINOLIZINIUM CHLORIDE
- AC-118
- UNII-UOT4O1BYV8
- Berberine chloride (TN)
- FT-0622874
- NSC 163088
- CAS-633-65-8
- AI3-61834
- 633-65-8 (CHLORIDE)
- Tox21_110474_1
- SW196403-2
- HMS2235H16
- AKOS007930622
- Berberine chloride, European Pharmacopoeia (EP) Reference Standard
- Berberine chloride, United States Pharmacopeia (USP) Reference Standard
- CHEMBL12089
- GNF-PF-4545
- Berberine Hydrochloride,(S)
- CHEBI: 16118
- 16,17-dimethoxy-5,7-dioxa-13$l^{5}-azapentacyclo[11.8.0.0^{2,10}.0^{4,8}.0^{15,20}]henicosa-1(13),2,4(8),9,14,16,18,20-octaen-13-ylium chloride
- Tox21_200348
- 1ST40203A
- Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium,5,6-dihydro-9,10-dimethoxy-, chloride
- Berberine Chloride, Pharmaceutical Secondary Standard; Certified Reference Material
- KS-5294
- Berberine chloride, British Pharmacopoeia (BP) Reference Standard
- BERBERINUM [HPUS]
- NSC-646666
- CAS: 638-65-8
- NCGC00094858-02
- Berbinium, 7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-, chloride
- DTXCID404602
- Berberinum
- SCHEMBL153906
- NSC646666
- SMR001233240
- Q-100261
- Natural Yellow 18 (chloride)
- HMS3373L14
- 9,10-dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-iumchloride
- HMS3336C05
- NSC 646666
- Berbinium,8,13,13a-tetradehydro-9.10-dimethoxy-2,3-(methylene dioxy)-, chloride
- VKJGBAJNNALVAV-UHFFFAOYSA-M
- SR-01000711827-4
- BERBERINE HYDROCHLORIDE [WHO-DD]
- HMS1569F14
- NSC757795
- HMS2096F14
- 16,17-dimethoxy-5,7-dioxa-13lambda5-azapentacyclo[11.8.0.0^{2,10}.0^{4,8}.0^{15,20}]henicosa-1(21),2(10),3,8,13,15(20),16,18-octaen-13-ylium chloride
- SR-01000711827
- 5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium chloride
- EN300-116212
- Berberine chloride hydrate, technical, >=90% (AT)
- NCGC00016526-07
- NCGC00094858-01
- Q-100731
- HMS500N07
- Pharmakon1600-01500811
- Benzo(g)-1,3-benzodioxolo(5,6-a)quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride
- HMS1921I18
- Prestwick_91
- 633-65-8
- HMS2210A06
- SR-01000711827-6
- CCG-39622
- DTXSID8024602
- NCGC00016526-02
- EINECS 211-195-9
- SPECTRUM1500811
- dimethoxy[?] chloride
- HMS3655F20
- MLS002153890
- 9,10-dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride
- 16,17-dimethoxy-5,7-dioxa-13-azoniapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-1(13),2,4(8),9,14,16,18,20-octaene;chloride
- Tox21_110474
- NCGC00091896-01
- CS-3214
- A834344
- SY076593
- 5,6-Dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo(5,6-a)quinolizinium chloride hydrate
- BERBERINE CHLORIDE [USP-RS]
- CHEBI:31271
- Z1494829513
- NSC-757795
- Benzo[g]-1,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride
- Berberinchlorid
- DTXCID3010820
- 16,17-dimethoxy-5,7-dioxa-13-azoniapentacyclo(11.8.0.02,10.04,8.015,20)henicosa-1(13),2,4(8),9,14,16,18,20-octaene;chloride
- UNII-266464AEJZ
- BERBERINE CHLORIDE DIHYDRATE [MI]
- Benzo(g)-1,3-benzodioxolo(5,6-a)quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride, dihydrate
- Berbinium, 7,8,13,13a-tetradehydro-9.10-dimethoxy-2,3-(methylene dioxy)-, chloride
- GLXC-04320
- Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 5,6-dihydro-9,10-dimethoxy-, chloride
- Berberinum Chloride
- DTXSID5030820
- BERBERINE CHLORIDE (USP-RS)
- Berberine hydrochloride bihydrate
- BENZO(G)-1,3-BENZODIOXOLO(5,6-A)QUINOLIZINIUM, 5,6-DIHYDRO-9,10-DIMETHOXY-, CHLORIDE, HYDRATE (1:1:2)
- Umbellatine chloride
- HY-18258R
- 5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium chloride;Berberine hydrochloride;7,8,13,13a-Tetradehydro-9,1 0-dimethoxy-2,3-(methylenedioxy)berbinium chloride
- FB64955
- Berberine (chloride) (Standard)
- Berberine chloride
-
- MDL： MFCD00633658
- Inchi： 1S/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;/p-1
- InChI Key： VKJGBAJNNALVAV-UHFFFAOYSA-M
- SMILES： [Cl-].O1COC2C1=CC1=C(C=2)C2C=C3C=CC(=C(C3=C[N+]=2CC1)OC)OC
- BRN： 3836585
Computed Properties
- Exact Mass: 371.09200
- Monoisotopic Mass: 371.0924357 g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 5
- Heavy Atom Count: 26
- Rotatable Bond Count: 2
- Complexity: 488
- Covalently-Bonded Unit Count: 2
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Molecular Weight: 371.8
- Surface Charge: 0
- Tautomer Count: nothing
- XLogP3: nothing
- Topological Polar Surface Area: 40.8
Experimental Properties
- Color/Form: Powder
- Density: 1.654
- Melting Point: 200 oC
- Boiling Point: No data available
- Flash Point: No data available
- Solubility: methanol: soluble
- Water Partition Coefficient: Dissolve in cold water
- PSA: 40.80000
- LogP: 0.10030
- Solubility: It is easily soluble in boiling water, slightly soluble in cold water, and almost insoluble in cold ethanol, chloroform, and diethyl ether.
- Sensitiveness: Easily absorb moisture
- Vapor Pressure: No data available
Berberine chloride Security Information
- Signal Word：Warning
- Hazard Statement： H302-H315-H319-H335
- Warning Statement： P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501
- Hazardous Material transportation number：UN 1544
- WGK Germany：2
- Hazard Category Code： S24/25:Prevent skin and eye contact.
- Safety Instruction： S24/25
- FLUKA BRAND F CODES：3-10
- RTECS：DR9866400
-
Hazardous Material Identification：
- Packing Group：III
- Hazard Level：6.1(b)
- Risk Phrases：R20/21/22
- Packing Group：III
- Safety Term：6.1(b)
- HazardClass：6.1(b)
- PackingGroup：III
- TSCA：Yes
- Storage Condition：Please store the product under the recommended conditions in the Certificate of Analysis.
Berberine chloride Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| MedChemExpress | HY-18258-10mM*1mLinDMSO |
Berberine chloride |
633-65-8 | 99.66% | 10mM*1mLinDMSO |
￥730 | 2023-07-26 | |
| MedChemExpress | HY-18258-100mg |
Berberine chloride |
633-65-8 | 99.92% | 100mg |
￥660 | 2025-04-16 | |
| MedChemExpress | HY-18258-1g |
Berberine chloride |
633-65-8 | 99.66% | 1g |
￥1500 | 2023-05-18 | |
| MedChemExpress | HY-18258-5g |
Berberine chloride |
633-65-8 | 99.66% | 5g |
￥3500 | 2023-05-18 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | LP841-100g |
Berberine chloride |
633-65-8 | 97% | 100g |
￥614.0 | 2022-07-29 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | LP841-25g |
Berberine chloride |
633-65-8 | 97% | 25g |
￥186.0 | 2022-07-29 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | LP841-1g |
Berberine chloride |
633-65-8 | 97% | 1g |
￥35.0 | 2022-07-29 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | LP841-5g |
Berberine chloride |
633-65-8 | 97% | 5g |
￥111.0 | 2022-07-29 | |
| ChemFaces | CFN99562-20mg |
Berberine hydrochloride |
633-65-8 | >=98% | 20mg |
$30 | 2021-07-22 | |
| HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI | BZP0151-20mg |
Berberine chloride |
633-65-8 | HPLC≥98% | 20mg |
￥100元 | 2023-09-15 |
Berberine chloride Suppliers
Amadis Chemical Company Limited
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(CAS:633-65-8)Berberine chloride
Order Number:A834344
Stock Status:in Stock
Quantity:500g
Purity:99%
Pricing Information Last Updated:Monday, 2 September 2024 15:37
Price ($):233.0
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Hubei Cuiyuan Biotechnology Co.,Ltd
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(CAS:633-65-8)Berberine hydrochloride
Order Number:CRN1123
Stock Status:in Stock
Quantity:20mg
Purity:98%
Pricing Information Last Updated:Tuesday, 2 April 2024 16:53
Price ($):30
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Suzhou Senfeida Chemical Co., Ltd
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(CAS:633-65-8)Berberine hydrochloride
Order Number:sfd8504
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:35
Price ($):discuss personally
Email:[email protected]
Tiancheng Chemical (Jiangsu) Co., Ltd
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(CAS:633-65-8)Berberine hydrochloride
Order Number:LE10248;LE1261
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:02
Price ($):discuss personally
Email:[email protected]
Berberine chloride Related Literature
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Pik-Ling Lam,Kenneth Ka-Ho Lee,Stanton Hon-Lung Kok,Gregory Yin-Ming Cheng,Xiao-Ming Tao,Desmond Kwok-Po Hau,Marcus Chun-Wah Yuen,Kim-Hung Lam,Roberto Gambari,Chung-Hin Chui,Raymond Siu-Ming Wong Soft Matter 2012 8 5027
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Yavuz Yagiz,Gary P. Wang,Liwei Gu Food Funct. 2022 13 12135
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Ferenc Zsila,Judit Kámán,Borbála Bogányi,Dávid Józsvai Org. Biomol. Chem. 2011 9 4127
-
B. E. Ellis Nat. Prod. Rep. 1988 5 581
