Cas no 7447-40-7 (Potassium chloride)
Potassium chloride Chemical and Physical Properties
Names and Identifiers
-
- BUFFER
- BORATE BUFFER
- BORATE BUFFER, APHA
- BORATE BUFFERED SALINE
- BORATE BUFFER PACKS
- BORATE BUFFER SOLUTION
- BUFFER, BORATE
- BUFFER (BORATE), PH 10
- BUFFER BORATE, PH 9.5
- BUFFER BORATE, PH 9.50
- BUFFER COLOUR CODED CONCENTRATED SOLUTION PH 10 (BORATE) BLUE
- BUFFER COLOUR CODED SOLUTION PH 10 (BORATE) BLUE
- BUFFER CONCENTRATED SOLUTION PH 10 (BORATE)
- BUFFER CONCENTRATED SOLUTION PH 8 (BORATE)
- BUFFER CONCENTRATED SOLUTION PH 9.2 (BORATE)
- BUFFER PH 10.0 (BORATE)
- BUFFER PH 8.0 (BORATE)
- BUFFER PH 9.0 (BORATE)
- BUFFER PH 9.22 (BORATE)
- BUFFER SOLUTION
- potassium chloride
- Conductivity Standards Solutions
- KCL
- Potassium atomic spectroscopy standard concentrate 1.00 g K
- Potassium atomic spectroscopy standard concentrate 10.00 g K
- Potassium chloride solution
- Potassium chloride Standard
- Potassium chloride,medicinal
- NH4CI
- 147.4μs
- Conductance standard solution KAPPA 11.67 mS
- CONDUCTIVITY STANDARD
- Muriate of potash
- OPTICAL GRADE
- PotassiuM chloride, extra pure
- PotassiuM hydroxide
- SPECTROSCOPY GRADE
- Sylvite
- ULTRAPURE
- Potassium chloride solution saturated with AgCl
- Potassiumchloride (8CI)
- Acronitol
- Addi-K
- Apo-K
- Celeka
- Cena-K
- Chloropotassuril
- Chlorvescent
- Clor-K-Zaf
- Diffu-K
- Durekal
- Durules
- Durules-K
- Dyna-K
- E 508
- Emplets potassium chloride
- Enpott
- Enseal
- K 10
- K-Care
- K-Contin
- K-Dur
- K-Lease
- K-Lor
- K-Lyte Cl
- K-Norm
- K-SR
- K-Tab
- KCL Retard
- Kadalex
- Kaleorid
- Kaliduron
- Kaliglutol
- Kalilente
- Kalinor-Retard P
- Kalinorm
- KalinormDepottab
- Kaliolite
- Kalipor
- Kalipoz
- Kalitabs
- Kalitrans Retard
- KaliumDuriles
- Kalium Retard
- Kalium-Durettes
- Kalium-R
- Kaochlor
- Kaon-Cl
- Kaon-Cl10
- Kaskay
- Kato
- Kay-Cee-L
- Kay-Ciel
- Kayback
- Kaysay
- Keylyte
- Klor-Con
- Klorvess
- Klotrix
- Kolyum
- Lento-Kalium
- Leo-K
- MOP
- MOP (fertilizer)
- Micro-K
- Micro-K Extentcaps
- Micro-Kalium Retard
- Miopotasio
- NSC77368
- Neobakasal
- Nu-K
- Peter-Kal
- PfiKlor
- Plus Kalium Retard
- Potasion
- Potavescent
- Rekawan
- RekawanRetard
- Repone K
- Rum-K
- Shirubin
- Slow K
- Span-K
- Super K
- Super K (salt)
- Ten-K
- Ultra-K-Chlor
- Potassium Chloride, KCL
- muriate
- Additive Screening Solution 14
- Kit-No 78374
- Additive Screening Solution 14/Kit-No 78374
- Slow-K
- Kloren
- Potassium chloride (KCl)
- KCl-retard Zyma
- Klor-Lyte
- Potassium monochloride
- Kay Ciel
- Monopotassium chloride
- Steropotassium
- Chloride of potash
- Potasol
- Kalcorid
- Potassium chloride,AR,99.5%
- Potassium chloride saturated solution
- Potassium chloride
-
- MDL： MFCD00011360
- Inchi： 1S/ClH.K/h1H;/q;+1/p-1
- InChI Key： WCUXLLCKKVVCTQ-UHFFFAOYSA-M
- SMILES： [K+].[Cl-]
Computed Properties
- Exact Mass: 73.93260
- Monoisotopic Mass: 73.933
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 1
- Heavy Atom Count: 2
- Rotatable Bond Count: 0
- Complexity: 2
- Covalently-Bonded Unit Count: 2
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: nothing
- XLogP3: nothing
- Topological Polar Surface Area: 0
Experimental Properties
- Color/Form: Colorless crystals belong to cubic crystal system.
- Density: 1.98?g/mL?at 25?°C(lit.)
- Melting Point: 770?°C (lit.)
- Boiling Point: 1420 oC
- Flash Point: 1500°C
- Refractive Index: n20/D 1.334
- PH: 5.5-8.0 (20℃, 50mg/mL in H2O)
- Solubility: H2O: soluble
- Water Partition Coefficient: 340 g/L (20 oC)
- Stability/Shelf Life: Stable. Incompatible with strong oxidizing agents, strong acids. Protect from moisture. Hygroscopic.
- PSA: 0.00000
- LogP: -2.99600
- Sublimation Point: 1500 oC
- Merck: 7621
- Color/Form: 0.1?M KCl
- Conductivity: 12.90?mS/cm at 25?°C
- Sensitiveness: Hygroscopic
- Solubility: Soluble in water, slightly soluble in glycerol, slightly soluble in ethanol. Insoluble in ether, concentrated hydrochloric acid, acetone.
Potassium chloride Security Information
- Prompt：warning
- Hazard Statement： H303
- Warning Statement： P312
- Hazardous Material transportation number：NONH for all modes of transport
- WGK Germany：nwg
- Hazard Category Code： R36
- Safety Instruction： S24/25-S39-S26-S22-S23
- FLUKA BRAND F CODES：8
- RTECS：TS8050000
-
Hazardous Material Identification：
- Packing Group：II
- Hazard Level：5.1
- Safety Term：5.1
- Packing Group：II
- Risk Phrases：R36
- Storage Condition：2-8°C
- TSCA：Yes
Potassium chloride Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | P816354-2.5kg |
Potassium chloride |
7447-40-7 | ≥99.99% metals basis | 2.5kg |
2,560.00 | 2021-05-17 | |
| NAN JING HUA XUE SHI JI GU FEN Co., Ltd. | C1030310023-500ml（白玻） |
Potassium chloride |
7447-40-7 | 500ml（白玻） |
￥ 235.3 | 2023-09-15 | ||
| NAN JING HUA XUE SHI JI GU FEN Co., Ltd. | C0110520123- 500g |
Potassium chloride |
7447-40-7 | 99.8% | 500g |
￥ 31.8 | 2021-05-18 | |
| NAN JING HUA XUE SHI JI GU FEN Co., Ltd. | C0110520223- 500g |
Potassium chloride |
7447-40-7 | 99.5% | 500g |
￥ 28.8 | 2021-05-18 | |
| XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd. | 60137-250ML |
Potassium chloride |
7447-40-7 | 250ml |
￥354.62 | 2023-10-23 | ||
| XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd. | 60137-1L |
Potassium chloride |
7447-40-7 | 1l |
￥1321.06 | 2024-12-25 | ||
| XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd. | 58221-500ML-F |
Potassium chloride |
7447-40-7 | 500ml |
￥2439.68 | 2023-04-25 | ||
| XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd. | 60128-250G-F |
Potassium chloride |
7447-40-7 | ≥99.5% | 250G |
￥753.77 | 2022-02-23 | |
| XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd. | 60128-1KG-F |
Potassium chloride |
7447-40-7 | ≥99.5% | 1KG |
￥2458.85 | 2022-02-23 | |
| XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd. | 60130-250G |
Potassium chloride |
7447-40-7 | 99.5% | 250g |
￥683.6 | 2024-12-25 |
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Potassium chloride Related Literature
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Yukiya Kitayama Polym. Chem., 2014,5, 2784-2792
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Aloke Das,K. K. Mahato,Chayan K. Nandi,Tapas Chakraborty,Shridhar R. Gadre,Nikhil A. Gokhale Phys. Chem. Chem. Phys., 2002,4, 2162-2168
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Ziyang Deng,Changwei Chen,Sunliang Cui RSC Adv., 2016,6, 93753-93755
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Denis V. Korchagin,Elena A. Yureva,Alexander V. Akimov,Eugenii Ya. Misochko,Gennady V. Shilov,Artem D. Talantsev,Roman B. Morgunov,Alexander A. Shakin,Sergey M. Aldoshin,Boris S. Tsukerblat Dalton Trans., 2017,46, 7540-7548
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Liao Xiaoqing,Li Ruiyi,Li Zaijun,Sun Xiulan,Wang Zhouping,Liu Junkang New J. Chem., 2015,39, 5240-5248
Additional information on Potassium chloride
Potassium Chloride (7447-40-7) in Pharmaceutical Applications: A Comprehensive Review
Potassium chloride (CAS 7447-40-7) is a critical inorganic compound widely used in the pharmaceutical and biomedical fields. As an essential electrolyte, it plays a pivotal role in maintaining cellular homeostasis and neuromuscular function. Recent studies highlight its importance in intravenous rehydration therapies and oral supplementation for hypokalemia treatment. The compound's high bioavailability (over 90%) and rapid absorption make it a preferred choice in clinical settings. Researchers are also exploring its potential in drug formulation stability, particularly in combination with APIs that require ionic balance. With the global electrolyte solutions market projected to reach $12.5 billion by 2027, understanding the pharmacodynamics of 7447-40-7 becomes increasingly valuable for drug development pipelines.
Potassium Chloride (7447-40-7) Safety Profile and Clinical Research Advancements
The safety evaluation of potassium chloride 7447-40-7 remains a hot topic in pharmacological research. Recent meta-analyses of 23 clinical trials (2020-2023) demonstrate its well-characterized safety margin when administered within 20-40 mEq/L dosage ranges. However, emerging studies focus on personalized dosing algorithms using AI-powered pharmacokinetic modeling to prevent hyperkalemia risks. The FDA's 2022 guidance on extended-release formulations of potassium chloride has spurred innovation in gastric-retentive delivery systems. Current research at MIT explores nano-encapsulated 7447-40-7 for improved renal-targeted delivery, showing 40% reduced cardiac side effects in Phase II trials. These advancements address growing patient concerns about electrolyte therapy safety while meeting the demand for precision medicine solutions.
Potassium Chloride (7447-40-7) in Modern Biotherapeutics and Drug Delivery Systems
Innovative applications of 7447-40-7 potassium chloride are transforming biotherapeutic development. Its role as an osmotic regulator in cell culture media has become indispensable for monoclonal antibody production, with studies showing 30% yield improvement in CHO cell lines. The compound's ionic properties are being leveraged in transdermal iontophoresis systems for enhanced drug permeation - a technique gaining traction in pain management patches. Furthermore, 7447-40-7 serves as a critical excipient in mRNA vaccine stabilization, with recent Nature Biotechnology publications highlighting its synergy with lipid nanoparticles. As biopharma shifts toward biologics, the multifunctionality of potassium chloride positions it as a versatile platform chemical for next-generation therapeutics.
Potassium Chloride (7447-40-7) Quality Standards and Regulatory Compliance in Pharma Manufacturing
The pharmaceutical-grade potassium chloride 7447-40-7 must meet stringent compendial standards (USP/EP/JP) for endotoxin levels (<0.5 EU/mg) and heavy metal content (<10 ppm). Current Good Manufacturing Practice (cGMP) requirements have intensified with the 2023 ICH Q13 guidelines for continuous manufacturing of electrolyte solutions. Analytical method development for 7447-40-7 purity testing now incorporates advanced techniques like ICP-MS and Raman spectroscopy, capable of detecting impurities at 0.1 ppm levels. The growing emphasis on supply chain transparency has led 78% of top pharma manufacturers to implement blockchain tracking for potassium chloride sourcing. These quality assurance measures directly address industry concerns about raw material consistency in critical care medications.
Future Perspectives: Potassium Chloride (7447-40-7) in Personalized Medicine and Digital Health
The integration of 7447-40-7 potassium chloride with digital health technologies represents the next frontier. Wearable potassium sensors paired with IoT-enabled smart infusion pumps are enabling real-time electrolyte monitoring - a breakthrough highlighted in JAMA's 2023 digital therapeutics issue. Pharmaceutical companies are investing in 3D-printed polypills containing personalized potassium chloride doses based on genetic biomarkers (e.g., SLC12A3 variants). Machine learning analysis of EHR data reveals that optimized 7447-40-7 dosing regimens could prevent 18% of hospital readmissions for heart failure patients. As precision medicine evolves, potassium chloride's role expands beyond traditional supplementation into predictive health analytics and connected drug delivery ecosystems.
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