Cas no 627526-35-6 (1,3,2-Dioxaborolane, 2-(4-fluoro-1-naphthalenyl)-4,4,5,5-tetramethyl-)

1,3,2-Dioxaborolane, 2-(4-fluoro-1-naphthalenyl)-4,4,5,5-tetramethyl-, is a fluorinated naphthalene-derived boronic ester commonly employed in Suzuki-Miyaura cross-coupling reactions. Its key advantages include enhanced stability under typical reaction conditions due to the tetramethyl substitution on the dioxaborolane ring, which minimizes protodeboronation. The 4-fluoro-naphthalenyl moiety offers improved electronic properties for selective coupling reactions, making it valuable in pharmaceutical and materials science applications. The compound’s crystalline nature facilitates handling and purification, while its well-defined reactivity profile ensures consistent performance in synthetic workflows. Suitable for use in both academic and industrial settings, it serves as a reliable intermediate for constructing complex fluorinated aromatic systems.
1,3,2-Dioxaborolane, 2-(4-fluoro-1-naphthalenyl)-4,4,5,5-tetramethyl- structure
627526-35-6 structure
Product Name:1,3,2-Dioxaborolane, 2-(4-fluoro-1-naphthalenyl)-4,4,5,5-tetramethyl-
CAS No:627526-35-6
MF:C16H18BFO2
MW:272.122328281403
MDL:MFCD11520119
CID:855201
PubChem ID:22240116
Update Time:2025-06-08

1,3,2-Dioxaborolane, 2-(4-fluoro-1-naphthalenyl)-4,4,5,5-tetramethyl- Chemical and Physical Properties

Names and Identifiers

    • 1,3,2-Dioxaborolane, 2-(4-fluoro-1-naphthalenyl)-4,4,5,5-tetramethyl-
    • 2-(1-FLUORONAPHTHALEN-4-YL)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE
    • 2-(4-Fluoronaphthalen-1-yl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane
    • SCHEMBL5781133
    • 4-Fluoronaphthalene-1-boronic acid pinacol ester
    • JYOPNVFIMNCXRZ-UHFFFAOYSA-N
    • E87437
    • 2-(4-fluoro-naphthalen-1-yl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane
    • 627526-35-6
    • CAB52635
    • AKOS017561895
    • MFCD11520119
    • CS-0189252
    • EN300-368482
    • 4-Fluoronaphtalene-1-boronic acid pinacol ester
    • DTXSID70623705
    • 2-(4-Fluoronaphthalen-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
    • MDL： MFCD11520119
    • Inchi： 1S/C16H18BFO2/c1-15(2)16(3,4)20-17(19-15)13-9-10-14(18)12-8-6-5-7-11(12)13/h5-10H,1-4H3
    • InChI Key： JYOPNVFIMNCXRZ-UHFFFAOYSA-N
    • SMILES： FC1=CC=C(B2OC(C)(C)C(C)(C)O2)C2C=CC=CC=21

Computed Properties

  • Exact Mass: 271.14204
  • Monoisotopic Mass: 272.1383881g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 20
  • Rotatable Bond Count: 1
  • Complexity: 356
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 18.5?2

Experimental Properties

  • PSA: 18.46

1,3,2-Dioxaborolane, 2-(4-fluoro-1-naphthalenyl)-4,4,5,5-tetramethyl- Security Information

1,3,2-Dioxaborolane, 2-(4-fluoro-1-naphthalenyl)-4,4,5,5-tetramethyl- Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
Chemenu
CM215744-5g
2-(4-Fluoronaphthalen-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
 627526-35-6 97%
5g
 $150 2021-08-04
BAI LING WEI Technology Co., Ltd.
122523-1G
2-(1-Fluoronaphthalen-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, 98%
 627526-35-6 98%
1G
 ￥ 595 2022-04-26
BAI LING WEI Technology Co., Ltd.
122523-5G
2-(1-Fluoronaphthalen-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, 98%
 627526-35-6 98%
5G
 ￥ 2082 2022-04-26
A2B Chem LLC
AG70219-5g
2-(1-FLUORONAPHTHALEN-4-YL)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE
 627526-35-6 >96%
5g
 $369.00 2024-04-19
abcr
AB517901-1 g
4-Fluoronaphthalene-1-boronic acid pinacol ester, 97%; .
 627526-35-6 97%
1g
 €147.00 2023-04-17
abcr
AB517901-5 g
4-Fluoronaphthalene-1-boronic acid pinacol ester, 97%; .
 627526-35-6 97%
5g
 €401.40 2023-04-17
eNovation Chemicals LLC
Y1253638-10g
2-(1-FLUORONAPHTHALEN-4-YL)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE
 627526-35-6 98%
10g
 $430 2024-06-06
Aaron
AR00EDZR-250mg
2-(1-FLUORONAPHTHALEN-4-YL)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE
 627526-35-6 98%
250mg
 $40.00 2025-02-10
Aaron
AR00EDZR-1g
2-(1-FLUORONAPHTHALEN-4-YL)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE
 627526-35-6 98%
1g
 $108.00 2025-02-10
A2B Chem LLC
AG70219-1g
2-(1-FLUORONAPHTHALEN-4-YL)-4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE
 627526-35-6 97%
1g
 $101.00 2023-12-30

1,3,2-Dioxaborolane, 2-(4-fluoro-1-naphthalenyl)-4,4,5,5-tetramethyl- Related Literature

Related Categories

627526-35-6 (1,3,2-Dioxaborolane, 2-(4-fluoro-1-naphthalenyl)-4,4,5,5-tetramethyl-) Related Products

Recommended suppliers
Henan Dongyan Pharmaceutical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Henan Dongyan Pharmaceutical Co., Ltd
Zhejiang Brunova Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Zhejiang Brunova Technology Co., Ltd.
Jinta Yudi Pharmaceutical Technology Co., Ltd.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Bulk
Jinta Yudi Pharmaceutical Technology Co., Ltd.
Shaanxi pure crystal photoelectric technology co. LTD
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
Shaanxi pure crystal photoelectric technology co. LTD
HANGZHOU BAIS CHEMICAL TECHNOLOGY CO., LTD.
Gold Member
Audited Supplier Audited Supplier
CN Supplier
Reagent
HANGZHOU BAIS CHEMICAL TECHNOLOGY CO., LTD.