Cas no 627-06-5 (Propylurea)

Propylurea (C4H10N2O) is a urea derivative where a propyl group replaces one hydrogen atom on the nitrogen. This modification enhances its solubility in organic solvents compared to urea, making it useful in synthetic chemistry and pharmaceutical applications. Propylurea serves as an intermediate in the synthesis of more complex compounds, including agrochemicals and active pharmaceutical ingredients (APIs). Its stable crystalline form and predictable reactivity under mild conditions facilitate controlled reactions. The compound’s structural flexibility allows for further functionalization, broadening its utility in heterocycle formation and polymer chemistry. Proper handling is advised due to potential sensitivity to moisture and heat.
Propylurea structure
Propylurea structure
Product Name:Propylurea
CAS No:627-06-5
MF:C4H10N2O
MW:102.135000705719
MDL:MFCD00014793
CID:39225
PubChem ID:12303
Update Time:2025-05-25

Propylurea Chemical and Physical Properties

Names and Identifiers

    • 1-Propylurea
    • Propylurea
    • n-Propylurea
    • 1-n-propylurea
    • EINECS 210-981-9
    • Propyl-harnstoff
    • propyl-urea
    • Urea,N-propyl
    • UREA,PROPYL
    • NS00035139
    • propyl urea
    • AKOS000200297
    • 627-06-5
    • BRN 1743060
    • F71407
    • EN300-17480
    • MFCD00014793
    • NSC 73471
    • N'-propylurea
    • DTXSID2060830
    • A833940
    • n-propyl urea
    • Urea, N-propyl-
    • FT-0632644
    • Q27237068
    • CS-0207277
    • UREA, PROPYL-
    • Z56943581
    • NSC73471
    • NSC-73471
    • FS-4086
    • UNII-0PK51J4AV7
    • 0PK51J4AV7
    • SCHEMBL23287
    • PROPYLUREA, N-
    • DB-054253
    • 4-04-00-00482 (Beilstein Handbook Reference)
    • STL575890
    • DTXCID4043488
    • MDL: MFCD00014793
    • Inchi: 1S/C4H10N2O/c1-2-3-6-4(5)7/h2-3H2,1H3,(H3,5,6,7)
    • InChI Key: ZQZJKHIIQFPZCS-UHFFFAOYSA-N
    • SMILES: O=C(N)NCCC

Computed Properties

  • Exact Mass: 102.07900
  • Monoisotopic Mass: 102.079313
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 7
  • Rotatable Bond Count: 3
  • Complexity: 62.7
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 55.1
  • Surface Charge: 0
  • Tautomer Count: 3
  • XLogP3: nothing

Experimental Properties

  • Color/Form: White lens powder
  • Density: 1.0739 (rough estimate)
  • Melting Point: 107-109 oC
  • Boiling Point: 158.1?°C at 760 mmHg
  • Flash Point: 49.4 oC
  • Refractive Index: 1.4386 (estimate)
  • Water Partition Coefficient: Soluble in water.
  • PSA: 55.12000
  • LogP: 1.15590
  • Solubility: Soluble in water.
  • Vapor Pressure: 2.7±0.3 mmHg at 25°C

Propylurea Security Information

Propylurea Pricemore >>

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Propylurea Suppliers

Amadis Chemical Company Limited
Gold Member
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(CAS:627-06-5)Propylurea
Order Number:A833940
Stock Status:in Stock
Quantity:100g
Purity:99%
Pricing Information Last Updated:Monday, 2 September 2024 15:35
Price ($):224.0

Propylurea Related Literature

Additional information on Propylurea

Propylurea (CAS No. 627-06-5): Chemical Properties, Applications, and Recent Research Developments

Propylurea, a chemical compound with the CAS number 627-06-5, is a derivative of urea that has garnered significant attention in the field of chemical and pharmaceutical research. This compound, characterized by its molecular formula C?H?N?O?, exhibits unique properties that make it a valuable intermediate in various synthetic processes. The structural integrity of Propylurea, featuring a propyl group attached to a urea backbone, contributes to its versatility in chemical reactions and applications.

The synthesis of Propylurea typically involves the reaction between propylamine and carbamic acid or its derivatives. This process highlights the compound's role as a building block in organic synthesis. The reaction conditions, including temperature and catalyst selection, play a crucial role in determining the yield and purity of the final product. Advanced synthetic methodologies have been developed to optimize these conditions, ensuring high efficiency and minimal byproduct formation.

In recent years, Propylurea has found applications in the development of agrochemicals, pharmaceuticals, and specialty chemicals. Its reactivity allows for further functionalization, making it a key intermediate in the synthesis of more complex molecules. For instance, Propylurea has been utilized in the production of herbicides and fungicides due to its ability to undergo various chemical transformations that enhance its biological activity.

One of the most compelling aspects of Propylurea is its potential in pharmaceutical research. The urea moiety in its structure is known to interact with biological targets, making it a valuable scaffold for drug design. Recent studies have explored Propylurea derivatives as inhibitors of enzymes involved in metabolic pathways relevant to diseases such as diabetes and cancer. These investigations have demonstrated promising results in preclinical trials, indicating the therapeutic potential of Propylurea-based compounds.

The chemical properties of Propylurea also make it an interesting candidate for material science applications. Its ability to form stable complexes with metal ions has been exploited in the development of catalysts and coordination polymers. These materials exhibit enhanced catalytic activity and selectivity, which are crucial for industrial processes requiring high efficiency and environmental sustainability.

Recent research has further expanded the applications of Propylurea by exploring its role in green chemistry initiatives. The development of eco-friendly synthetic routes for Propylurea has reduced its environmental impact while maintaining high product quality. These advancements align with global efforts to promote sustainable chemical manufacturing practices.

The pharmaceutical industry has also seen significant advancements in the use of Propylurea derivatives. Researchers have identified novel analogs that exhibit improved pharmacokinetic properties, including enhanced bioavailability and reduced toxicity. These findings have opened new avenues for drug development, particularly in treating chronic diseases that require long-term therapeutic intervention.

In conclusion, Propylurea (CAS No. 627-06-5) is a multifaceted compound with diverse applications across multiple industries. Its unique chemical properties and reactivity make it an indispensable intermediate in organic synthesis. Recent research developments underscore its potential in pharmaceuticals, agrochemicals, and material science, highlighting its significance as a research tool and industrial chemical.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:627-06-5)Propylurea
A833940
Purity:99%
Quantity:100g
Price ($):224.0
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