Cas no 19757-64-3 (cyclopropylurea)

Cyclopropylurea is a heterocyclic organic compound featuring a cyclopropyl group attached to a urea moiety. Its rigid cyclopropyl ring imparts unique steric and electronic properties, making it a valuable intermediate in pharmaceutical and agrochemical synthesis. The compound's structural characteristics enhance binding affinity and metabolic stability in active ingredients, particularly in drug discovery applications. Cyclopropylurea serves as a versatile building block for the development of biologically active molecules, including protease inhibitors and receptor modulators. Its stability under various reaction conditions allows for flexible functionalization, enabling tailored modifications for target-specific applications. The compound is typically handled under standard laboratory conditions, requiring appropriate safety measures due to its potential reactivity.
cyclopropylurea structure
cyclopropylurea structure
Product Name:cyclopropylurea
CAS No:19757-64-3
MF:C4H8N2O
MW:100.119120597839
MDL:MFCD01569844
CID:234608
PubChem ID:272626
Update Time:2025-07-01

cyclopropylurea Chemical and Physical Properties

Names and Identifiers

    • Urea,N-cyclopropyl-
    • cyclopropylurea
    • N-CYCLOPROPYLUREA
    • 1-cyclopropylurea
    • AC1L6S21
    • AC1Q4ZW4
    • AC1Q5JFX
    • Cyclopropylharnstoff
    • Cyclopropyl-harnstoff
    • cyclopropyl-urea
    • N-Cyclopropyl-harnstoff
    • NSC117244
    • SureCN687674
    • (Carbamoylamino)cyclopropane, Ureidocyclopropane
    • Z57000532
    • Urea, N-cyclopropyl-
    • BS-12686
    • NSC-117244
    • SCHEMBL687674
    • DTXSID00297670
    • CS-0073680
    • cyclopropyl urea
    • F8880-2529
    • 19757-64-3
    • CLMGCKCDSPUQEE-UHFFFAOYSA-N
    • AKOS000200343
    • MFCD01569844
    • EN300-13158
    • D73868
    • DB-244326
    • MDL: MFCD01569844
    • Inchi: 1S/C4H8N2O/c5-4(7)6-3-1-2-3/h3H,1-2H2,(H3,5,6,7)
    • InChI Key: CLMGCKCDSPUQEE-UHFFFAOYSA-N
    • SMILES: O=C(N)NC1CC1

Computed Properties

  • Exact Mass: 100.06374
  • Monoisotopic Mass: 100.064
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 7
  • Rotatable Bond Count: 1
  • Complexity: 87.7
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: -0.5
  • Topological Polar Surface Area: 55.1?2

Experimental Properties

  • Density: 1.17
  • Melting Point: 123-124 °C
  • Boiling Point: 179.7°Cat760mmHg
  • Flash Point: 62.5°C
  • Refractive Index: 1.519
  • PSA: 55.12

cyclopropylurea Pricemore >>

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cyclopropylurea Suppliers

Amadis Chemical Company Limited
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(CAS:19757-64-3)cyclopropylurea
Order Number:A1146528
Stock Status:in Stock
Quantity:5g/10g/25g
Purity:99%
Pricing Information Last Updated:Thursday, 29 August 2024 23:04
Price ($):346.0/524.0/1185.0
Zibo Yurui Biotechnology
Gold Member
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(CAS:19757-64-3)N-CYCLOPROPYLUREA
Order Number:LE368
Stock Status:in Stock
Quantity:10G;1KG
Purity:99%
Pricing Information Last Updated:Thursday, 4 June 2026 14:15
Price ($):inquiry

Additional information on cyclopropylurea

Cyclopropylurea: A Comprehensive Overview

Cyclopropylurea, also known by its CAS number 19757-64-3, is a chemical compound that has garnered significant attention in various scientific and industrial applications. This compound is a derivative of urea, with a cyclopropyl group attached, making it unique in terms of its chemical structure and properties. The cyclopropylurea molecule is characterized by its ability to form hydrogen bonds, which contributes to its versatility in different chemical reactions and applications.

Recent studies have highlighted the potential of cyclopropylurea in the field of medicinal chemistry. Researchers have explored its role as a building block for the synthesis of bioactive compounds, particularly in the development of new drug candidates. The compound's ability to act as a template for assembling complex molecular architectures has made it a valuable tool in drug design. For instance, cyclopropylurea derivatives have been investigated for their potential as inhibitors of certain enzymes, which could lead to novel therapeutic agents.

In addition to its role in drug discovery, cyclopropylurea has also found applications in materials science. Its unique chemical properties make it an ideal candidate for the synthesis of advanced materials, such as polymers and coatings. Recent advancements in polymer chemistry have demonstrated that cyclopropylurea can be used to create materials with enhanced mechanical and thermal stability. These materials hold promise for use in high-performance applications, such as aerospace and automotive industries.

The synthesis of cyclopropylurea involves a multi-step process that typically begins with the reaction of cyclopropane derivatives with urea precursors. This process requires precise control over reaction conditions to ensure high yields and purity. Recent research has focused on optimizing these synthesis methods to make them more efficient and environmentally friendly. For example, the use of catalytic systems and green chemistry principles has been explored to reduce waste and energy consumption during the production of cyclopropylurea.

Another area where cyclopropylurea has shown potential is in agrochemicals. Its ability to interact with biological systems makes it a candidate for the development of pesticides and herbicides. However, extensive testing is required to ensure that these applications are safe for both human health and the environment. Researchers are currently investigating the environmental fate and toxicity of cyclopropylurea derivatives to assess their suitability for agricultural use.

From a structural standpoint, cyclopropylurea exhibits interesting properties due to the strained ring system of the cyclopropane group. This strain can lead to unique reactivity patterns, which have been exploited in various organic transformations. For instance, the compound has been used as a substrate in cycloaddition reactions, which are fundamental processes in organic chemistry. These reactions have enabled the construction of complex molecules with high precision.

Moreover, cyclopropylurea has been studied for its potential in catalysis. Its ability to coordinate with metal ions makes it a promising candidate for designing catalysts with high activity and selectivity. Recent research has focused on using cyclopropylurea as a ligand in transition metal complexes, which could find applications in industrial catalysis processes such as olefin polymerization and hydrogenation.

In terms of spectroscopic analysis, cyclopropylurea exhibits distinct absorption bands that make it amenable to various analytical techniques. Techniques such as infrared spectroscopy (IR), nuclear magnetic resonance (NMR), and mass spectrometry (MS) have been employed to characterize its structure and purity. These analyses are crucial for ensuring the quality of cyclopropylurea products used in research and industrial settings.

The global demand for compounds like cyclopropylurea is driven by their versatility across multiple industries. As research continues to uncover new applications and improve existing ones, the significance of this compound is expected to grow further. Its role in advancing fields such as drug discovery, materials science, and catalysis underscores its importance as a key player in modern chemistry.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:19757-64-3)cyclopropylurea
A1146528
Purity:99%/99%/99%
Quantity:5g/10g/25g
Price ($):346.0/524.0/1185.0
Email
Zibo Yurui Biotechnology
(CAS:19757-64-3)N-CYCLOPROPYLUREA
LE368
Purity:99%
Quantity:10G;1KG
Price ($):Inquiry
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