• 1. Base-free conversion of glycerol to methyl lactate using a multifunctional catalytic system consisting of Au–Pd nanoparticles on carbon nanotubes and Sn-MCM-41-XS
  Zhenchen Tang,Dina G. Boer,Ali Syariati,Mihaela Enache,Petra Rudolf,Hero J. Heeres,Paolo P. Pescarmona Green Chem. 2019 21 4115
• 2. Factors affecting activity and selectivity in the oxidation of glycerol promoted by platinum catalysts
  Yang Li,Francisco Zaera Catal. Sci. Technol. 2015 5 3773
• 3. Catalytic conversion of lignocellulosic biomass to fine chemicals and fuels
  Chun-Hui Zhou,Xi Xia,Chun-Xiang Lin,Dong-Shen Tong,Jorge Beltramini Chem. Soc. Rev. 2011 40 5588
• 4. Promotion effect of Mg on a post-synthesized Sn-Beta zeolite for the conversion of glucose to methyl lactate
  Xiaomei Yang,Bin Lv,Tianliang Lu,Yunlai Su,Lipeng Zhou Catal. Sci. Technol. 2020 10 700
• 5. Synergetic effects of bimetals in modified beta zeolite for lactic acid synthesis from biomass-derived carbohydrates
  Meng Xia,Wenjie Dong,Minyan Gu,Cheng Chang,Zheng Shen,Yalei Zhang RSC Adv. 2018 8 8965

Comprehensive Overview of trans-2,5-Bis(hydroxymethyl)-1,4-dioxane-2,5-diol (CAS No. 62147-49-3)

trans-2,5-Bis(hydroxymethyl)-1,4-dioxane-2,5-diol (CAS No. 62147-49-3) is a versatile organic compound with a unique cyclic structure, featuring two hydroxyl groups and two hydroxymethyl groups symmetrically positioned on a 1,4-dioxane ring. This compound has garnered significant attention in recent years due to its potential applications in green chemistry, biodegradable materials, and pharmaceutical intermediates. Its molecular formula, C₆H₁₂O₆, highlights its oxygen-rich nature, making it a candidate for sustainable chemical synthesis.

The compound’s structural features, particularly its trans-configuration, contribute to its stability and reactivity, which are critical for applications in polymer chemistry and cosmetic formulations. Researchers have explored its role as a cross-linking agent in hydrogels, where its hydroxyl groups facilitate hydrogen bonding and network formation. This property aligns with the growing demand for eco-friendly materials in industries such as personal care and biomedical engineering.

In the context of sustainable development, trans-2,5-Bis(hydroxymethyl)-1,4-dioxane-2,5-diol is often discussed alongside bio-based solvents and renewable feedstocks. Its synthesis from furfural derivatives, a byproduct of agricultural waste, underscores its alignment with the circular economy paradigm. This connection resonates with current trends in green manufacturing and carbon footprint reduction, topics frequently searched by environmentally conscious consumers and industry professionals.

Another area of interest is the compound’s potential in drug delivery systems. Its ability to form hydrogen bonds with active pharmaceutical ingredients (APIs) makes it a candidate for controlled-release formulations. This application is particularly relevant given the rising demand for precision medicine and nanotechnology-based therapies, which dominate academic and industrial research discussions.

From a safety and regulatory perspective, trans-2,5-Bis(hydroxymethyl)-1,4-dioxane-2,5-diol is classified as non-hazardous under standard handling conditions, making it suitable for large-scale industrial use. Its low toxicity and biodegradability further enhance its appeal in consumer products and environmental applications. These attributes are frequently highlighted in life cycle assessments (LCAs) and sustainability reports, which are increasingly prioritized by regulatory bodies and corporate stakeholders.

In summary, trans-2,5-Bis(hydroxymethyl)-1,4-dioxane-2,5-diol (CAS No. 62147-49-3) represents a promising compound at the intersection of green chemistry, material science, and pharmaceutical innovation. Its multifaceted applications and alignment with global sustainability goals ensure its continued relevance in both academic research and industrial practice.

• 7504-90-7(1,4-Dioxane,2,5-dimethoxy-2,5-dimethyl-)
• 23147-59-3(3,6-bis(hydroxymethyl)-1,4-dioxane-2,5-diol)
• 923028-75-5(3,6,8-Trioxabicyclo[3.2.1]octane, 5-methyl-, (1R,5S)-)
• 87937-03-9(3,6,8-Trioxabicyclo[3.2.1]octane, 5-methyl-, (1S)-)
• 859814-72-5(1,4-Dioxane,2,5-dimethoxy-2,5-bis(methoxymethyl)-)
• 51795-26-7(1,4-Dioxane-2,5-dimethanol,3,6-dihydroxy-, (2R,3S,5S,6R)-rel-)
• 26776-70-5(1,3-Dihydroxyacetone dimer)
• 89727-88-8(2,5-bis(hydroxymethyl)-1,4-dioxane-2,5-diol)
• 854841-36-4(p-Dioxane, 2,5-diethoxy-2,5-dimethyl- (5CI))
• 56886-08-9(1,4-Dioxane-2-methanol, 3-hydroxy-)