• 1. Evolutionary de novo design of phenothiazine derivatives for dye-sensitized solar cells?
  Vishwesh Venkatraman,Marco Foscato,Vidar R. Jensen,Bj?rn K?re Alsberg J. Mater. Chem. A, 2015,3, 9851-9860
• 2. Exciplex emission from the mixed dimer of naphthalene and 2-cyanonaphthalene in a supersonic jet
  Aloke Das,K. K. Mahato,Chayan K. Nandi,Tapas Chakraborty,Shridhar R. Gadre,Nikhil A. Gokhale Phys. Chem. Chem. Phys., 2002,4, 2162-2168
• 3. Evolution of cellulose into flexible conductive green electronics: a smart strategy to fabricate sustainable electrodes for supercapacitors
  Tengfei Yu,Yuehan Wu,Wei Li,Bin Li RSC Adv., 2014,4, 34134-34143
• 4. Establishing empirical design rules of nucleic acid templates for the synthesis of silver nanoclusters with tunable photoluminescence and functionalities towards targeted bioimaging applications?
  Jason Y. C. Lim,Yong Yu,Guorui Jin,Kai Li,Yi Lu,Jianping Xie Nanoscale Adv., 2020,2, 3921-3932
• 5. Excellent electrochemical performance of LiFe0.4Mn0.6PO4 microspheres produced using a double carbon coating process?
  Yong Ping Huang,Tao Tao,Zheng Chen,Wei Han,Ying Wu,Chunjiang Kuang,Shaoxiong Zhou,Ying Chen J. Mater. Chem. A, 2014,2, 18831-18837

3,6-Bis(hydroxymethyl)-1,4-dioxane-2,5-diol (CAS No. 23147-59-3): Properties, Applications, and Industry Insights

3,6-Bis(hydroxymethyl)-1,4-dioxane-2,5-diol (CAS No. 23147-59-3) is a unique polyhydroxy compound gaining attention in specialty chemical applications. This white crystalline solid belongs to the family of sugar alcohols and polyol derivatives, characterized by its four hydroxyl groups and dioxane ring structure. The compound's molecular formula is C₆H₁₂O₆, with a molecular weight of 180.16 g/mol, making it structurally similar to some carbohydrate derivatives but with distinct chemical properties.

The growing interest in bio-based chemicals and sustainable materials has positioned 3,6-bis(hydroxymethyl)-1,4-dioxane-2,5-diol as a promising candidate for various industrial applications. Researchers are particularly interested in its potential as a green chemistry building block, given its renewable origin possibilities and multifunctional nature. The compound's stability in aqueous solutions and compatibility with numerous organic solvents enhances its versatility in formulation chemistry.

In the pharmaceutical sector, 3,6-bis(hydroxymethyl)dioxanediol (a common abbreviated name) shows potential as an excipient due to its hydrophilic properties and low toxicity profile. Formulators are exploring its use in controlled-release systems where its hydroxyl groups can participate in hydrogen bonding with active pharmaceutical ingredients. The cosmetic industry has also shown interest in this polyol for its possible humectant properties and skin-conditioning effects, aligning with the current market demand for multifunctional cosmetic ingredients.

The material science field has identified CAS 23147-59-3 as a potential monomer for biodegradable polymers. Its multiple hydroxyl groups allow for polycondensation reactions to create novel polymeric materials with tunable properties. Recent studies suggest possible applications in creating water-soluble films and biodegradable packaging materials, addressing the global push for sustainable alternatives to conventional plastics.

From a synthetic chemistry perspective, 3,6-bis(hydroxymethyl)-1,4-dioxane-2,5-diol serves as a valuable intermediate. Its symmetrical structure with four reactive sites makes it suitable for creating complex molecular architectures through selective functionalization. Chemists are particularly interested in its potential for creating dendrimer cores and crosslinking agents, especially in the development of specialty coatings and adhesives.

The compound's safety profile has been partially characterized, showing favorable results in preliminary toxicological assessments. This aspect is crucial for industries seeking safer chemical alternatives, especially in consumer-facing applications. However, comprehensive safety data continues to be developed as research into this compound expands across different application areas.

Market analysts note growing commercial interest in 23147-59-3, particularly from manufacturers of specialty chemicals in Asia and North America. The compound's price point and availability have shown improvement in recent years, making it more accessible for research and development purposes. Industry reports suggest potential growth in demand for this chemical as its applications become more established in various sectors.

Environmental considerations play a significant role in the compound's appeal. 3,6-Bis(hydroxymethyl)-1,4-dioxane-2,5-diol shows promise in meeting green chemistry principles, with preliminary biodegradability studies yielding positive results. This characteristic aligns well with current regulatory trends favoring environmentally benign chemicals, particularly in the European Union and North American markets.

Analytical characterization of 3,6-bis(hydroxymethyl)dioxanediol typically involves techniques such as HPLC for purity assessment, NMR spectroscopy for structural confirmation, and mass spectrometry for molecular weight verification. The compound's melting point ranges between 160-165°C, with good thermal stability below this range, making it suitable for various processing conditions.

Storage and handling recommendations for CAS 23147-59-3 follow standard practices for polyhydroxy compounds. The material should be kept in a cool, dry place in tightly sealed containers to prevent moisture absorption. While not classified as hazardous under current regulations, proper laboratory precautions should be observed when handling the powdered form to avoid dust generation.

Future research directions for 3,6-bis(hydroxymethyl)-1,4-dioxane-2,5-diol include exploring its potential in energy storage applications, particularly as a component in electrolyte formulations for batteries. The compound's ability to coordinate metal ions and its electrochemical stability make it an interesting candidate for next-generation energy storage materials.

In conclusion, 3,6-Bis(hydroxymethyl)-1,4-dioxane-2,5-diol (CAS No. 23147-59-3) represents an emerging specialty chemical with diverse potential applications across multiple industries. Its unique structural features, combined with favorable physicochemical properties and growing commercial availability, position it as a compound worth watching in the evolving landscape of functional chemicals. As research continues to uncover new applications and manufacturing processes improve, this polyhydroxy dioxane derivative may find its way into numerous everyday products and advanced technologies.

• 62147-49-3(trans-2,5-Bis(hydroxymethyl)-1,4-dioxane-2,5-diol)
• 499782-36-4(1,4-Dioxan-2-ol, 3-methoxy-3-methyl- (9CI))
• 859814-72-5(1,4-Dioxane,2,5-dimethoxy-2,5-bis(methoxymethyl)-)
• 51795-26-7(1,4-Dioxane-2,5-dimethanol,3,6-dihydroxy-, (2R,3S,5S,6R)-rel-)
• 26776-70-5(1,3-Dihydroxyacetone dimer)
• 499782-35-3(1,4-Dioxan-2-ol, 3-ethoxy-3-methyl-)
• 89727-88-8(2,5-bis(hydroxymethyl)-1,4-dioxane-2,5-diol)
• 859814-70-3(1,4-Dioxane,2,5-dimethoxy-3,6-bis(methoxymethyl)-)
• 56886-08-9(1,4-Dioxane-2-methanol, 3-hydroxy-)
• 32909-97-0(1,4-Dioxane-2,3-diol, 5-methyl-)