Cas no 621-31-8 (3-(Ethylamino)phenol)

3-(Ethylamino)phenol is an organic compound featuring a phenol core substituted with an ethylamino group at the meta position. This structure imparts unique reactivity, making it a valuable intermediate in organic synthesis, particularly for the preparation of dyes, pharmaceuticals, and specialty chemicals. Its ethylamino group enhances solubility in polar solvents, facilitating reactions in aqueous or mixed-phase systems. The compound’s balanced electron-donating properties also make it useful in catalytic processes and as a building block for heterocyclic compounds. High purity grades are available to ensure consistent performance in sensitive applications. Proper handling is advised due to potential reactivity with oxidizing agents.
3-(Ethylamino)phenol structure
3-(Ethylamino)phenol structure
Product Name:3-(Ethylamino)phenol
CAS No:621-31-8
MF:C8H11NO
MW:137.179042100906
MDL:MFCD00059617
CID:503580
PubChem ID:578991
Update Time:2025-05-27

3-(Ethylamino)phenol Chemical and Physical Properties

Names and Identifiers

    • 3-(Ethylamino)phenol
    • 3-ETHYLAMINOPHENOL
    • Phenol, 3-(ethylamino)-
    • BRN 2637735
    • CCRIS 4640
    • m-(Ethylamino)phenol
    • Phenol, 3-(ethylamino)- (9CI)
    • Phenol, m-(ethylamino)-
    • DTXCID005270
    • AKOS009158754
    • F16135
    • CCG-357921
    • AS-47782
    • 0-13-00-00408 (Beilstein Handbook Reference)
    • UNII-L26AT05W85
    • m-Ethylaminophenol
    • Phenol, 3-ethylamino-
    • 3-(ethylamino) phenol
    • DTXSID6025270
    • N-Ethyl-3-aminophenol; N-Ethyl-m-aminophenol; m-(Ethylamino)phenol
    • L26AT05W85
    • SCHEMBL55730
    • EINECS 210-678-1
    • NS00043707
    • m-hydroxyphenyl-ethylamine
    • SB75500
    • MFCD00059617
    • SCHEMBL2306420
    • 3-(N-ethyl) aminophenol
    • META-ETHYLAMINOPHENOL
    • Q27282613
    • n-ethyl-m-aminophenol
    • 621-31-8
    • EN300-174170
    • N-ETHYL-3-AMINOPHENOL
    • MDL: MFCD00059617
    • Inchi: 1S/C8H11NO/c1-2-9-7-4-3-5-8(10)6-7/h3-6,9-10H,2H2,1H3
    • InChI Key: TVKZDKSHNITMRZ-UHFFFAOYSA-N
    • SMILES: OC1=CC=CC(=C1)NCC

Computed Properties

  • Exact Mass: 137.08413
  • Monoisotopic Mass: 137.084063974g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 2
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 2
  • Complexity: 95.3
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1.9
  • Topological Polar Surface Area: 32.3?2

Experimental Properties

  • Density: 1.0630 (rough estimate)
  • Melting Point: 62°C
  • Boiling Point: 252.03°C (rough estimate)
  • Refractive Index: 1.5560 (estimate)
  • PSA: 32.26

3-(Ethylamino)phenol Security Information

  • Hazardous Material transportation number:1759
  • Hazard Category Code: 34
  • Safety Instruction: 26-36/37/39

3-(Ethylamino)phenol Pricemore >>

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3-(Ethylamino)phenol Suppliers

Amadis Chemical Company Limited
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(CAS:621-31-8)3-(Ethylamino)phenol
Order Number:A1168414
Stock Status:in Stock
Quantity:10g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 01:11
Price ($):572.0

Additional information on 3-(Ethylamino)phenol

Recent Advances in the Study of 3-(Ethylamino)phenol (CAS: 621-31-8) in Chemical Biology and Pharmaceutical Research

3-(Ethylamino)phenol (CAS: 621-31-8) is a chemical compound of significant interest in the fields of chemical biology and pharmaceutical research. Recent studies have highlighted its potential as a key intermediate in the synthesis of bioactive molecules and its role in various biochemical pathways. This research brief aims to provide an overview of the latest findings related to this compound, focusing on its synthesis, applications, and biological activities.

One of the most notable advancements in the study of 3-(Ethylamino)phenol is its application in the development of novel therapeutic agents. Researchers have demonstrated its utility as a building block for the synthesis of compounds with potential antimicrobial and anticancer properties. For instance, a recent study published in the Journal of Medicinal Chemistry explored the compound's role in the synthesis of small-molecule inhibitors targeting specific enzymes involved in cancer progression.

In addition to its therapeutic potential, 3-(Ethylamino)phenol has been investigated for its biochemical interactions. A 2023 study in Biochemical Pharmacology revealed that the compound exhibits moderate inhibitory effects on certain cytochrome P450 enzymes, which are critical in drug metabolism. This finding has important implications for drug-drug interactions and the optimization of pharmacokinetic profiles in drug development.

The synthesis and characterization of 3-(Ethylamino)phenol have also seen significant progress. Recent methodologies emphasize greener and more efficient synthetic routes, reducing the environmental impact and improving yield. For example, a study in Organic Process Research & Development reported a novel catalytic process that enhances the selectivity and efficiency of 3-(Ethylamino)phenol production, making it more viable for large-scale pharmaceutical applications.

Despite these advancements, challenges remain in the widespread adoption of 3-(Ethylamino)phenol in drug development. Issues such as stability under physiological conditions and potential toxicity at higher concentrations require further investigation. Ongoing research aims to address these limitations through structural modifications and formulation strategies.

In conclusion, 3-(Ethylamino)phenol (CAS: 621-31-8) continues to be a compound of great interest in chemical biology and pharmaceutical research. Its versatility as a synthetic intermediate and its potential therapeutic applications make it a valuable focus for future studies. Continued exploration of its properties and mechanisms will likely yield further insights and innovations in drug discovery and development.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:621-31-8)3-(Ethylamino)phenol
A1168414
Purity:99%
Quantity:10g
Price ($):572.0
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