Cas no 620957-95-1 (Ethyl 4-Chloro-6-methyl-2-quinazolinecarboxylate)
Ethyl 4-Chloro-6-methyl-2-quinazolinecarboxylate is a versatile quinazoline derivative widely used in pharmaceutical and agrochemical research. Its molecular structure, featuring a chloro substituent at the 4-position and a methyl group at the 6-position, enhances its reactivity, making it a valuable intermediate in synthesizing biologically active compounds. The ethyl carboxylate moiety improves solubility in organic solvents, facilitating further functionalization. This compound exhibits potential as a precursor for antitumor, antimicrobial, and kinase inhibitor agents due to its quinazoline core, known for diverse pharmacological properties. Its high purity and stability under standard conditions ensure reliable performance in synthetic applications. Researchers favor it for its well-defined reactivity profile and compatibility with various coupling reactions.
620957-95-1 structure
Product Name:Ethyl 4-Chloro-6-methyl-2-quinazolinecarboxylate
CAS No:620957-95-1
MF:C12H11ClN2O2
MW:250.680941820145
MDL:MFCD12026444
CID:1636018
PubChem ID:23068383
Update Time:2025-07-02
Ethyl 4-Chloro-6-methyl-2-quinazolinecarboxylate Chemical and Physical Properties
Names and Identifiers
-
- Ethyl 4-chloro-6-methylquinazoline-2-carboxylate
- ETHYL 4-CHLORO-6-METHYL-2-QUINAZOLINECARBOXYLATE
- MFCD12026444
- SCHEMBL3287907
- 620957-95-1
- NZKXQPUEYVPGPX-UHFFFAOYSA-N
- 4-chloro-2-ethoxycarbonyl-6-methylquinazoline
- DTXSID70630196
- DB-073051
- Ethyl 4-Chloro-6-methyl-2-quinazolinecarboxylate
-
- MDL： MFCD12026444
- Inchi： 1S/C12H11ClN2O2/c1-3-17-12(16)11-14-9-5-4-7(2)6-8(9)10(13)15-11/h4-6H,3H2,1-2H3
- InChI Key： NZKXQPUEYVPGPX-UHFFFAOYSA-N
- SMILES： ClC1=C2C=C(C)C=CC2=NC(C(=O)OCC)=N1
Computed Properties
- Exact Mass: 250.051
- Monoisotopic Mass: 250.051
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 4
- Heavy Atom Count: 17
- Rotatable Bond Count: 3
- Complexity: 288
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 52.1A^2
- XLogP3: 3.4
Experimental Properties
- Density: 1.301±0.06 g/cm3 (20 oC 760 Torr),
- Boiling Point: 405.3±37.0 °C at 760 mmHg
- Flash Point: 198.9±26.5 °C
- Refractive Index: 1.605
- Solubility: Almost insoluble (0.03 g/l) (25 o C),
- Vapor Pressure: 0.0±0.9 mmHg at 25°C
Ethyl 4-Chloro-6-methyl-2-quinazolinecarboxylate Security Information
- Signal Word：warning
- Hazard Statement： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Warning Statement： P264+P280+P305+P351+P338+P337+P313
- Safety Instruction： H303+H313+H333
- Storage Condition：storage at -4℃ (1-2weeks), longer storage period at -20℃ (1-2years)
Ethyl 4-Chloro-6-methyl-2-quinazolinecarboxylate Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | E941233-10mg |
Ethyl 4-Chloro-6-methyl-2-quinazolinecarboxylate |
620957-95-1 | 10mg |
$ 50.00 | 2022-06-05 | ||
| TRC | E941233-50mg |
Ethyl 4-Chloro-6-methyl-2-quinazolinecarboxylate |
620957-95-1 | 50mg |
$ 95.00 | 2022-06-05 | ||
| TRC | E941233-100mg |
Ethyl 4-Chloro-6-methyl-2-quinazolinecarboxylate |
620957-95-1 | 100mg |
$ 135.00 | 2022-06-05 | ||
| Apollo Scientific | OR309394-250mg |
Ethyl 4-chloro-6-methyl-2-quinazolinecarboxylate |
620957-95-1 | 250mg |
￡127.00 | 2025-02-20 | ||
| abcr | AB293653-100 mg |
Ethyl 4-chloro-6-methyl-2-quinazolinecarboxylate |
620957-95-1 | 100 mg |
€110.00 | 2023-07-20 | ||
| abcr | AB293653-250 mg |
Ethyl 4-chloro-6-methyl-2-quinazolinecarboxylate |
620957-95-1 | 250 mg |
€178.00 | 2023-07-20 | ||
| SHENG KE LU SI SHENG WU JI SHU | sc-294521-250 mg |
Ethyl 4-chloro-6-methyl-2-quinazolinecarboxylate, |
620957-95-1 | 250MG |
￥1,279.00 | 2023-07-11 | ||
| SHENG KE LU SI SHENG WU JI SHU | sc-294521A-500 mg |
Ethyl 4-chloro-6-methyl-2-quinazolinecarboxylate, |
620957-95-1 | 500MG |
￥2,181.00 | 2023-07-11 | ||
| SHENG KE LU SI SHENG WU JI SHU | sc-294521-250mg |
Ethyl 4-chloro-6-methyl-2-quinazolinecarboxylate, |
620957-95-1 | 250mg |
￥1279.00 | 2023-09-05 | ||
| SHENG KE LU SI SHENG WU JI SHU | sc-294521A-500mg |
Ethyl 4-chloro-6-methyl-2-quinazolinecarboxylate, |
620957-95-1 | 500mg |
￥2181.00 | 2023-09-05 |
Ethyl 4-Chloro-6-methyl-2-quinazolinecarboxylate Related Literature
-
Supaporn Sawadjoon,Joseph S. M. Samec Org. Biomol. Chem., 2011,9, 2548-2554
-
Teresita Carrillo-Hernández,Philippe Schaeffer,Pierre Albrecht Chem. Commun., 2001, 1976-1977
-
Jingquan Liu,Huiyun Liu,Zhongfan Jia,Volga Bulmus,Thomas P. Davis Chem. Commun., 2008, 6582-6584
-
Inês S. Albuquerque,Hélia F. Jeremias,Miguel Chaves-Ferreira,Dijana Matak-Vinkovic,Omar Boutureira,Carlos C. Rom?o Chem. Commun., 2015,51, 3993-3996
-
Jianyao Huang,Dong Gao,Zhihui Chen,Weifeng Zhang Polym. Chem., 2021,12, 2471-2480
620957-95-1 (Ethyl 4-Chloro-6-methyl-2-quinazolinecarboxylate) Related Products
- 34632-69-4(Ethyl 4-chloroquinazoline-2-carboxylate)
- 1189106-02-2(Ethyl 4-chloro-7-fluoroquinazoline-2-carboxylate)
- 364385-74-0(Ethyl 4-chloro-6-methoxyquinazoline-2-carboxylate)
- 944902-14-1(4-Chloroquinazoline-2-carboxylic acid)
- 1188085-66-6(Methyl 6-bromo-4-chloroquinazoline-2-carboxylate)
- 1189107-22-9(Ethyl 4-chloro-7-methoxyquinazoline-2-carboxylate)
- 150449-99-3(4,6-Dichloro-quinazoline-2-carboxylic Acid ethyl ester)
- 1159976-38-1(Ethyl 6-bromo-4-chloroquinazoline-2-carboxylate)
- 1189106-09-9(Ethyl 4,7-dichloroquinazoline-2-carboxylate)
- 1189105-79-0(Ethyl 7-bromo-4-chloroquinazoline-2-carboxylate)
Recommended suppliers
Zhejiang Brunova Technology Co., Ltd.
Gold Member
Audited Supplier
CN Supplier
Bulk
Hebei Liye chemical Co.,Ltd
Gold Member
Audited Supplier
CN Supplier
Bulk
Henan Dongyan Pharmaceutical Co., Ltd
Gold Member
Audited Supplier
CN Supplier
Bulk
Enjia Trading Co., Ltd
Gold Member
Audited Supplier
CN Supplier
Bulk
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier
CN Supplier
Bulk