Cas no 6157-06-8 (H-Asp-Glu-OH)
H-Asp-Glu-OH Chemical and Physical Properties
Names and Identifiers
-
- L-Glutamic acid, L-a-aspartyl-
- Asp-Glu
- H-Asp-Glu-OH
- L-ASPARTIC ACID-L-GLUTAMIC ACID
- aspartylglutamate
- Asp-Glu-OH
- L-aspartyl-glutamic acid
- L-aspartyl-L-glutamic acid
- L-Asp-L-Glu
- L-Asp-L-Glu-OH
- N-Aspartyl-L-glutamic acid
- N-Aspartylglutamic acid
-
- MDL： MFCD00057829
- Inchi： 1S/C9H14N2O7/c10-4(3-7(14)15)8(16)11-5(9(17)18)1-2-6(12)13/h4-5H,1-3,10H2,(H,11,16)(H,12,13)(H,14,15)(H,17,18)
- InChI Key： CKAJHWFHHFSCDT-UHFFFAOYSA-N
- SMILES： NC(C(NC(C(=O)O)CCC(=O)O)=O)CC(=O)O
Computed Properties
- Exact Mass: 262.08000
- Hydrogen Bond Donor Count: 5
- Hydrogen Bond Acceptor Count: 9
- Heavy Atom Count: 18
- Rotatable Bond Count: 9
Experimental Properties
- Density: 1.530±0.06 g/cm3 (20 oC 760 Torr),
- Melting Point: 150-155 oC
- Solubility: Soluble (999 g/l) (25 o C),
- PSA: 167.02000
- LogP: -0.68620
H-Asp-Glu-OH Customs Data
- HS CODE：2924199090
- Customs Data：
China Customs Code:
2924199090Overview:
2924199090. Other acyclic amides(Including acyclic carbamates)(Including its derivatives and salts). VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%
Declaration elements:
Product Name, component content, use to, packing
Summary:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
H-Asp-Glu-OH Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | H017117-100mg |
H-Asp-Glu-OH |
6157-06-8 | 100mg |
$ 235.00 | 2022-06-04 | ||
| TRC | H017117-250mg |
H-Asp-Glu-OH |
6157-06-8 | 250mg |
$ 485.00 | 2022-06-04 | ||
| TRC | H017117-500mg |
H-Asp-Glu-OH |
6157-06-8 | 500mg |
$ 775.00 | 2022-06-04 | ||
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | A801599-250mg |
Asp-Glu |
6157-06-8 | 95% | 250mg |
￥2,500.00 | 2022-10-10 | |
| abcr | AB476577-250 mg |
H-Asp-Glu-OH; . |
6157-06-8 | 250MG |
€154.50 | 2022-05-20 | ||
| abcr | AB476577-1 g |
H-Asp-Glu-OH; . |
6157-06-8 | 1g |
€362.00 | 2022-05-20 | ||
| BAI LING WEI Technology Co., Ltd. | A1916-250MG |
Asp-Glu |
6157-06-8 | ≥95% (TLC) | 250MG |
￥ 1336 | 2022-04-26 | |
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | A99660-250mg |
H-Asp-Glu-OH |
6157-06-8 | 95% | 250mg |
￥2119.0 | 2024-07-18 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R026909-250mg |
Asp-Glu,95% |
6157-06-8 | 95% | 250mg |
￥2400 | 2024-05-22 | |
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | A801599-100mg |
Asp-Glu |
6157-06-8 | 95% | 100mg |
￥1,050.00 | 2022-10-10 |
H-Asp-Glu-OH Suppliers
Audited Supplier
H-Asp-Glu-OH Related Literature
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Chao-Han Cheng,Wen-Zhen Wang,Shie-Ming Peng,I-Chia Chen Phys. Chem. Chem. Phys., 2017,19, 25471-25477
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Vanessa dos Santos Pereira Montera,Camila Aparecida Borges Food Funct., 2021,12, 7699-7708
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Alexandre Vimont,Arnaud Travert,Philippe Bazin,Jean-Claude Lavalley,Marco Daturi,Christian Serre,Gérard Férey,Sandrine Bourrelly,Philip L. Llewellyn Chem. Commun., 2007, 3291-3293
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Eléonore Resongles,Corinne Casiot,Fran?oise Elbaz-Poulichet,Rémi Freydier,Odile Bruneel,Christine Piot,Sophie Delpoux,Aurélie Volant,Angélique Desoeuvre Environ. Sci.: Processes Impacts, 2013,15, 1536-1544
Additional information on H-Asp-Glu-OH
Introduction to L-Glutamic acid, L-a-aspartyl- (CAS No: 6157-06-8) and Its Emerging Applications in Modern Research
The compound L-Glutamic acid, L-a-aspartyl-, identified by the Chemical Abstracts Service Number (CAS No) 6157-06-8, represents a significant molecule in the realm of biochemical and pharmaceutical research. This dipeptide, composed of L-glutamic acid and L-aspartic acid, has garnered considerable attention due to its multifaceted roles in biological systems and its potential applications in therapeutic and nutraceutical contexts.
L-Glutamic acid itself is an essential amino acid involved in numerous physiological processes, including neurotransmission, protein synthesis, and metabolic regulation. Its ability to act as a neurotransmitter has made it a focal point in neuroscientific research. The addition of L-aspartic acid to form L-Glutamic acid, L-a-aspartyl- introduces additional biochemical interactions that enhance its utility in various synthetic pathways and biological functions.
Recent studies have highlighted the importance of this compound in the development of novel drug delivery systems. The unique structural properties of L-Glutamic acid, L-a-aspartyl- allow it to serve as a carrier for bioactive molecules, improving their solubility and bioavailability. This has been particularly relevant in the formulation of peptide-based therapeutics, where efficient delivery is critical for clinical efficacy.
The compound's role in enzyme inhibition has also been a subject of extensive research. By acting as a substrate or competitive inhibitor for various enzymes, L-Glutamic acid, L-a-aspartyl- can modulate metabolic pathways involved in inflammation, oxidative stress, and neurodegeneration. These findings have opened new avenues for the development of targeted therapies for conditions such as Alzheimer's disease and rheumatoid arthritis.
In the field of nutraceuticals, L-Glutamic acid, L-a-aspartyl- has been explored for its potential to enhance cognitive function. Its ability to cross the blood-brain barrier and influence neurotransmitter levels makes it a promising candidate for supplements aimed at improving memory and focus. Additionally, its role in glutathione synthesis—a key antioxidant—underscores its importance in maintaining cellular health.
The synthesis of L-Glutamic acid, L-a-aspartyl- has also seen advancements with the advent of green chemistry principles. Researchers are increasingly employing enzymatic catalysis and biocatalytic methods to produce this compound sustainably. These approaches not only reduce environmental impact but also improve yield and purity, making the compound more viable for industrial applications.
Another emerging area of research involves the use of L-Glutamic acid, L-a-aspartyl- in tissue engineering. Its structural properties enable it to serve as a scaffold for cell growth and differentiation, particularly in neural tissue regeneration. Preliminary studies suggest that this dipeptide can promote the survival and proliferation of neural stem cells, offering hope for new treatments for spinal cord injuries and neurodegenerative disorders.
The compound's interaction with immune cells has also been studied extensively. By modulating immune responses through its effects on glutamate receptors and signaling pathways, L-Glutamic acid, L-a-aspartyl- may play a role in immunomodulatory therapies. This has implications for treating autoimmune diseases and enhancing vaccine efficacy.
Future research directions may explore the potential synergistic effects of L-Glutamic acid, L-a-aspartyl- when combined with other bioactive compounds. Its ability to enhance drug absorption and reduce side effects could make it an invaluable component in combination therapies for complex diseases such as cancer and metabolic syndrome.
In conclusion, L-Glutamic acid, L-a-aspartyl- (CAS No: 6157-06-8) is a versatile compound with significant implications across multiple domains of biomedical research. Its unique biochemical properties continue to drive innovation in drug development, nutraceutical formulations, and tissue engineering. As our understanding of its mechanisms grows, so too will its applications in advancing human health and treating debilitating diseases.
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