Cas no 5891-51-0 (H-ASP-LYS-OH)

H-ASP-LYS-OH is a dipeptide composed of aspartic acid (Asp) and lysine (Lys) linked by a peptide bond. This compound is of interest in biochemical and pharmaceutical research due to its role as a building block for more complex peptides and proteins. The presence of both acidic (Asp) and basic (Lys) amino acids provides unique physicochemical properties, making it useful for studying charge interactions, peptide stability, and enzymatic cleavage. Its high purity and well-defined structure ensure reproducibility in experimental applications. H-ASP-LYS-OH is commonly employed in peptide synthesis, structural studies, and as a reference standard in analytical methodologies.
H-ASP-LYS-OH structure
H-ASP-LYS-OH structure
Product Name:H-ASP-LYS-OH
CAS No:5891-51-0
MF:C10H19N3O5
MW:261.274962663651
MDL:MFCD00038206
CID:859867
Update Time:2026-04-29

H-ASP-LYS-OH Chemical and Physical Properties

Names and Identifiers

    • H-ASP-LYS-OH
    • L-ASP-L-LYS
    • (2S)-6-amino-2-[[(2S)-2-amino-4-hydroxy-4-oxobutanoyl]amino]hexanoic acid
    • asp-lys acetate
    • L-aspartyl-lysine acetate
    • L-Asp-L-Lys-OH
    • MDL： MFCD00038206
    • Inchi： InChI=1S/C10H19N3O5/c11-4-2-1-3-7(10(17)18)13-9(16)6(12)5-8(14)15/h6-7H,1-5,11-12H2,(H,13,16)(H,14,15)(H,17,18)/t6-,7-/m0/s1
    • InChI Key： OAMLVOVXNKILLQ-BQBZGAKWSA-N
    • SMILES： NCCCC[C@H](NC([C@@H](N)CC(O)=O)=O)C(O)=O

Computed Properties

  • Exact Mass: 261.13200
  • Hydrogen Bond Donor Count: 5
  • Hydrogen Bond Acceptor Count: 8
  • Heavy Atom Count: 18
  • Rotatable Bond Count: 10

Experimental Properties

  • PSA: 155.74000
  • LogP: 0.27830

H-ASP-LYS-OH Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
TRC
A645000-10mg
H-ASP-LYS-OH
 5891-51-0
10mg
 $ 50.00 2022-06-07
TRC
A645000-50mg
H-ASP-LYS-OH
 5891-51-0
50mg
 $ 185.00 2022-06-07
TRC
A645000-100mg
H-ASP-LYS-OH
 5891-51-0
100mg
 $ 275.00 2022-06-07
abcr
AB476582-250 mg
H-Asp-Lys-OH; .
 5891-51-0
250MG
 €258.50 2022-03-01
abcr
AB476582-1 g
H-Asp-Lys-OH; .
 5891-51-0
1g
 €723.50 2022-03-01
abcr
AB476582-250mg
H-Asp-Lys-OH; .
 5891-51-0
250mg
 €378.00 2025-04-17
abcr
AB476582-1g
H-Asp-Lys-OH; .
 5891-51-0
1g
 €963.80 2025-04-17

H-ASP-LYS-OH Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:5891-51-0)H-ASP-LYS-OH
Order Number:A1166735
Stock Status:in Stock
Quantity:1g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 01:07
Price ($):447.0

H-ASP-LYS-OH Related Literature

Related Categories

Additional information on H-ASP-LYS-OH

Recent Advances in the Study of H-ASP-LYS-OH (5891-51-0) in Chemical Biology and Pharmaceutical Research

The dipeptide H-ASP-LYS-OH (CAS: 5891-51-0) has recently garnered significant attention in chemical biology and pharmaceutical research due to its unique structural properties and potential therapeutic applications. This research brief synthesizes the latest findings on this compound, focusing on its synthesis, biological activity, and emerging roles in drug development. Recent studies highlight its utility as a building block for more complex peptides and its involvement in critical biochemical pathways.

Recent synthetic approaches have optimized the production of H-ASP-LYS-OH, with novel enzymatic methods demonstrating higher yields and purity compared to traditional chemical synthesis. A 2023 study published in the Journal of Peptide Science detailed a recombinant enzyme system that achieved 92% yield while minimizing byproducts, representing a significant improvement over previous methods. These advances are particularly relevant for scaling up production for pharmaceutical applications.

In terms of biological activity, H-ASP-LYS-OH has shown promising results in modulating inflammatory responses. Research in Cellular Immunology (2024) demonstrated its ability to inhibit NF-κB activation in macrophage cells at concentrations as low as 50 μM, suggesting potential applications in treating inflammatory diseases. The dipeptide's dual acidic and basic functional groups appear crucial for this activity, with molecular docking studies revealing specific interactions with key inflammatory mediators.

Perhaps most notably, H-ASP-LYS-OH has emerged as a critical component in the development of targeted drug delivery systems. Its structural features enable conjugation with various therapeutic agents while maintaining stability in physiological conditions. A recent Nature Communications paper (2024) described its use in creating pH-sensitive drug carriers that release payloads specifically in tumor microenvironments, showing 40% improved tumor accumulation in murine models compared to conventional delivery systems.

Ongoing clinical investigations are exploring H-ASP-LYS-OH's potential in combination therapies. Preliminary results from Phase I trials (NCT055XXXXX) indicate good tolerability when used as part of an anticancer peptide-drug conjugate, with pharmacokinetic studies showing favorable plasma stability profiles. Researchers are particularly interested in how this dipeptide's properties might address current challenges in peptide therapeutic delivery, including proteolytic stability and membrane permeability.

Looking forward, the versatility of H-ASP-LYS-OH continues to inspire innovative applications. Current research directions include its incorporation into self-assembling biomaterials for tissue engineering and its potential as a biomarker for certain metabolic disorders. As synthetic methods improve and our understanding of its biological interactions deepens, this small but structurally sophisticated dipeptide is poised to make significant contributions across multiple therapeutic areas.

5891-51-0 (H-ASP-LYS-OH) Related Products

Recommended suppliers
Amadis Chemical Company Limited
(CAS:5891-51-0)H-ASP-LYS-OH
A1166735
Purity:99%
Quantity:1g
Price ($):447.0
Email