Cas no 615263-60-0 (ent-Rosuvastatin tert-Butyl Ester)

Technical Introduction: ent-Rosuvastatin tert-Butyl Ester ent-Rosuvastatin tert-Butyl Ester is a synthetic intermediate derived from the enantiomeric form of Rosuvastatin, a prominent statin used for cholesterol management. The tert-butyl ester moiety enhances stability and solubility, facilitating handling and purification in synthetic processes. This compound is particularly valuable in pharmaceutical research for studying structure-activity relationships and metabolic pathways of Rosuvastatin analogs. Its enantiomeric purity makes it useful for chiral separation studies and the development of stereoselective synthesis methods. The tert-butyl ester group also allows for controlled deprotection, enabling precise modifications in downstream applications. This intermediate is favored for its consistent quality and utility in advanced organic and medicinal chemistry research.
ent-Rosuvastatin tert-Butyl Ester structure
615263-60-0 structure
Product Name:ent-Rosuvastatin tert-Butyl Ester
CAS No:615263-60-0
MF:C26H36FN3O6S
MW:537.643949508667
MDL:MFCD24386499
CID:1065093
PubChem ID:11478210
Update Time:2025-10-29

ent-Rosuvastatin tert-Butyl Ester Chemical and Physical Properties

Names and Identifiers

    • ent-Rosuvastatin tert-Butyl Ester
    • ent-Rosuvastatin ter
    • tert-butyl (E,3S,5R)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate
    • C26H36FN3O6S
    • tert-butyl (E,3R,5S)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate
    • BCP13063
    • AKOS015896307
    • 615263-60-0
    • J-524818
    • (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[(methanesulfonyl) methylamino]-pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid tert-butyl ester
    • SCHEMBL1025730
    • A24806
    • Rosuvastatin tert-Butyl Ester
    • rel-tert-butyl (3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate
    • CS-0144285
    • IJHZGLLGELSZAF-OKLSWEBGSA-N
    • rel-tert-butyl(3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate
    • DTXSID10467120
    • tert-butyl (6E)-7-{4-(4-flurophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}(3R,5S)-3,5-dihydroxyhept-6-enoate
    • AMY4204
    • tert-Butyl rosuvastatin
    • MFCD08460212
    • AS-15047
    • AC-3415
    • D70551
    • (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[(methanesulfonyl) methylamino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid tert-butyl est
    • (3R,5S,E)-tert-butyl 7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate
    • tert-butyl (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate
    • 355806-00-7
    • AKOS015841661
    • D97190
    • (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[(methanesulfonyl) methylamino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid tert-butyl ester
    • SCHEMBL1025729
    • MDL： MFCD24386499
    • Inchi： 1S/C26H36FN3O6S/c1-16(2)23-21(13-12-19(31)14-20(32)15-22(33)36-26(3,4)5)24(17-8-10-18(27)11-9-17)29-25(28-23)30(6)37(7,34)35/h8-13,16,19-20,31-32H,14-15H2,1-7H3/b13-12+/t19-,20-/m1/s1
    • InChI Key： IJHZGLLGELSZAF-OKLSWEBGSA-N
    • SMILES： S(C)(N(C)C1=NC(C2C=CC(=CC=2)F)=C(/C=C/[C@H](C[C@H](CC(=O)OC(C)(C)C)O)O)C(C(C)C)=N1)(=O)=O

Computed Properties

  • Exact Mass: 537.23100
  • Monoisotopic Mass: 537.23088521g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 9
  • Heavy Atom Count: 37
  • Rotatable Bond Count: 12
  • Complexity: 865
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 2
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 1
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.9
  • Topological Polar Surface Area: 138?2

Experimental Properties

  • Density: 1.3±0.1 g/cm3
  • Melting Point: 134-136oC
  • Boiling Point: 704.2±70.0 °C at 760 mmHg
  • Flash Point: 379.7±35.7 °C
  • Solubility: DMSO (Slightly), Methanol (Slightly)
  • PSA: 138.30000
  • LogP: 4.73960
  • Vapor Pressure: 0.0±2.3 mmHg at 25°C

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ent-Rosuvastatin tert-Butyl Ester Suppliers

Amadis Chemical Company Limited
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(CAS:615263-60-0)ent-Rosuvastatin tert-Butyl Ester
Order Number:A937081
Stock Status:in Stock
Quantity:100mg
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 15:22
Price ($):1491.0

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Amadis Chemical Company Limited
(CAS:615263-60-0)ent-Rosuvastatin tert-Butyl Ester
A937081
Purity:99%
Quantity:100mg
Price ($):1491.0
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