Cas no 612-55-5 (2-Iodonaphthalene)

2-Iodonaphthalene (C??H?I) is a halogenated aromatic compound featuring an iodine substituent at the 2-position of the naphthalene ring. This compound is valued for its utility in organic synthesis, particularly as a versatile intermediate in cross-coupling reactions such as Suzuki-Miyaura and Sonogashira couplings. Its iodine moiety offers enhanced reactivity compared to other halides, enabling efficient functionalization of the naphthalene scaffold. The compound exhibits good stability under standard conditions, facilitating handling and storage. Its crystalline solid form and well-defined melting point ensure consistent purity, making it suitable for precise synthetic applications. 2-Iodonaphthalene is commonly employed in pharmaceuticals, materials science, and ligand design due to its robust reactivity and structural versatility.
2-Iodonaphthalene structure
2-Iodonaphthalene structure
Product Name:2-Iodonaphthalene
CAS No:612-55-5
MF:C10H7I
MW:254.067054986954
MDL:MFCD00021590
CID:513268
PubChem ID:329761311
Update Time:2025-11-07

2-Iodonaphthalene Chemical and Physical Properties

Names and Identifiers

    • 2-Iodonaphthalene
    • Naphthalene, 2-iodo-
    • beta-Iodonaphthalene
    • 2-Naphtyl iodide
    • 2-Naphthyl iodide
    • NSC 3786
    • Naphthalen-2-yl iodide
    • .beta.-Iodonaphthalene
    • FRNLBIWVMVNNAZ-UHFFFAOYSA-N
    • 2-iodonapthalene
    • NSC3786
    • 2-iodo-naphtalene
    • 2-iodo-naphthalene
    • 2-iodanylnaphthalene
    • BCP13447
    • 9164AB
    • VZ24807
    • EN000965
    • AK110894
    • ST2404072
    • MDL: MFCD00021590
    • Inchi: 1S/C10H7I/c11-10-6-5-8-3-1-2-4-9(8)7-10/h1-7H
    • InChI Key: FRNLBIWVMVNNAZ-UHFFFAOYSA-N
    • SMILES: IC1=CC=C2C=CC=CC2=C1

Computed Properties

  • Exact Mass: 253.95900
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 0
  • Heavy Atom Count: 11
  • Rotatable Bond Count: 0
  • Complexity: 133
  • XLogP3: 4.1
  • Topological Polar Surface Area: 0

Experimental Properties

  • Density: 1.7447 (rough estimate)
  • Melting Point: 52-56?°C
  • Boiling Point: 320°C (rough estimate)
  • Refractive Index: 1.7010 (estimate)
  • Solubility: Insuluble (4.1E-3 g/L) (25 oC),
  • PSA: 0.00000
  • LogP: 3.44440

2-Iodonaphthalene Security Information

2-Iodonaphthalene Customs Data

  • HS CODE:2903999090
  • Customs Data:

    China Customs Code:

    2903999090

    Overview:

    2903999090 Other aromatic halogenated derivatives. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:5.5% general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

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2-Iodonaphthalene Suppliers

Amadis Chemical Company Limited
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(CAS:612-55-5)2-Iodonaphthalene
Order Number:A833125
Stock Status:in Stock
Quantity:25g/100g
Purity:99%
Pricing Information Last Updated:Monday, 2 September 2024 15:31
Price ($):184.0/734.0
Suzhou Senfeida Chemical Co., Ltd
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(CAS:612-55-5)2-IODONAPHTHALENE
Order Number:sfd20437
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:38
Price ($):discuss personally

Additional information on 2-Iodonaphthalene

Professional Introduction to 2-Iodonaphthalene (CAS No. 612-55-5)

2-Iodonaphthalene, with the chemical name 2-Iodobenzene, is a significant compound in the field of organic synthesis and pharmaceutical research. Its molecular formula, C10H6I, underscores its role as an important intermediate in various chemical transformations. This compound, identified by the CAS number CAS No. 612-55-5, has garnered considerable attention due to its versatile applications in medicinal chemistry and material science.

The structural integrity of 2-Iodonaphthalene, featuring a naphthalene core substituted with an iodine atom at the 2-position, makes it a valuable reagent in cross-coupling reactions. These reactions are pivotal in constructing complex molecular architectures, which are often essential in the development of novel therapeutic agents. The iodine atom's presence facilitates its participation in palladium-catalyzed reactions, such as Suzuki-Miyaura and Stille couplings, enabling the formation of carbon-carbon bonds that are crucial for drug design.

In recent years, 2-Iodonaphthalene has been extensively studied for its potential in pharmaceutical applications. Researchers have leveraged its reactivity to develop new synthetic pathways for bioactive molecules. For instance, its use in the synthesis of antiviral and anticancer agents has shown promising results. The compound's ability to undergo selective functionalization has allowed chemists to tailor its structure for specific biological targets, enhancing its utility in drug discovery.

The compound's role extends beyond pharmaceuticals into the realm of materials science. Its incorporation into organic electronic materials has led to advancements in optoelectronic devices. The iodine substituent influences the electronic properties of naphthalene derivatives, making them suitable for applications in organic light-emitting diodes (OLEDs) and photovoltaic cells. This intersection of chemistry and technology highlights the multifaceted nature of 2-Iodonaphthalene.

Recent studies have also explored the environmental and toxicological aspects of 2-Iodonaphthalene. While it is not classified as a hazardous material, understanding its behavior under various conditions is essential for safe handling and disposal. Researchers are investigating its degradation pathways and potential impacts on ecosystems, ensuring that its use aligns with sustainable practices.

The industrial production of 2-Iodonaphthalene involves well-established synthetic routes that ensure high purity and yield. Manufacturers adhere to stringent quality control measures to meet the demands of both academic and industrial research sectors. The compound's commercial availability makes it accessible for a wide range of applications, fostering innovation across multiple disciplines.

Looking ahead, the future prospects of 2-Iodonaphthalene are bright, with ongoing research uncovering new possibilities for its use. Advances in synthetic methodologies and computational chemistry are expected to further enhance its utility in drug development and material science. As our understanding of molecular interactions deepens, compounds like 2-Iodonaphthalene will continue to play a pivotal role in advancing scientific knowledge and technological innovation.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:612-55-5)2-Iodonaphthalene
A833125
Purity:99%/99%
Quantity:25g/100g
Price ($):184.0/734.0
Email
Suzhou Senfeida Chemical Co., Ltd
(CAS:612-55-5)2-IODONAPHTHALENE
sfd20437
Purity:99.9%
Quantity:200kg
Price ($):Inquiry
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