Cas no 608523-94-0 (3-Amino-N-(Tertbutylbenzenesulfonamide)

3-Amino-N-(tert-butyl)benzenesulfonamide is a specialized sulfonamide derivative characterized by the presence of an amino group and a tert-butyl substituent on the benzenesulfonamide scaffold. This compound is of interest in synthetic and medicinal chemistry due to its potential as an intermediate in the preparation of biologically active molecules, including enzyme inhibitors and pharmaceutical agents. The tert-butyl group enhances steric bulk, which can influence binding affinity and metabolic stability, while the amino group provides a reactive site for further functionalization. Its well-defined structure and purity make it suitable for research applications requiring precise molecular modifications. The compound is typically handled under controlled conditions due to its reactive functional groups.
3-Amino-N-(Tertbutylbenzenesulfonamide structure
608523-94-0 structure
Product Name:3-Amino-N-(Tertbutylbenzenesulfonamide
CAS No:608523-94-0
MF:C10H16N2O2S
MW:228.311241149902
MDL:MFCD06660528
CID:528504
PubChem ID:3162838
Update Time:2025-06-08

3-Amino-N-(Tertbutylbenzenesulfonamide Chemical and Physical Properties

Names and Identifiers

    • 3-Amino-N-(tert-butyl)benzenesulfonamide
    • N-tert-Butyl 3-Aminophenylsulfonamide
    • 3-Amino-N-tert-butylbenzenesulfonamide
    • 3-Amino-N-tert-butyl-benzenesulfonamide
    • Benzenesulfonamide, 3-amino-N-(1,1-dimethylethyl)-
    • N-t-Butyl 3-aminobenzenesulfonamide
    • N-tert-Butyl3-Aminophenylsulfonamide
    • 3-AMINO-N-TERT-BUTYLBENZENE-1-SULFONAMIDE
    • [(3-aminophenyl)sulfonyl](tert-butyl)amine
    • KLQVFEHOLLUULE-UHFFFAOYSA-N
    • MFCD06660528
    • DB-002087
    • DTXSID30390320
    • CS-0059260
    • 3-Amino-N-(Tertbutylbenzenesulfonamide
    • 3-amino-N-(1,1-dimethylethyl)benzenesulfonamide
    • 608523-94-0
    • RWQ7RXG5JC
    • SY002394
    • 3-AMINO-N-T-BUTYLBENZENESULFONAMIDE
    • SCHEMBL2018411
    • AKOS000117812
    • EN300-11771
    • amino-N-(tert-butyl)benzenesulfonamide
    • AS-31149
    • Z99600238
    • AB26745
    • MDL: MFCD06660528
    • Inchi: 1S/C10H16N2O2S/c1-10(2,3)12-15(13,14)9-6-4-5-8(11)7-9/h4-7,12H,11H2,1-3H3
    • InChI Key: KLQVFEHOLLUULE-UHFFFAOYSA-N
    • SMILES: S(C1C=CC=C(C=1)N)(NC(C)(C)C)(=O)=O

Computed Properties

  • Exact Mass: 228.09300
  • Monoisotopic Mass: 228.09324893g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 15
  • Rotatable Bond Count: 3
  • Complexity: 300
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 1
  • Topological Polar Surface Area: 80.6

Experimental Properties

  • Boiling Point: 387.3 ℃ at 760 mmHg
  • PSA: 80.57000
  • LogP: 3.39850

3-Amino-N-(Tertbutylbenzenesulfonamide Security Information

  • Hazardous Material Identification: Xi
  • HazardClass:IRRITANT

3-Amino-N-(Tertbutylbenzenesulfonamide Customs Data

  • HS CODE:2935009090
  • Customs Data:

    China Customs Code:

    2935009090

    Overview:

    2935009090 Other sulphonates(Acyl)amine. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:6.5% general tariff:35.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

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3-Amino-N-(Tertbutylbenzenesulfonamide Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:608523-94-0)3-Amino-N-(Tertbutylbenzenesulfonamide
Order Number:A868871
Stock Status:in Stock
Quantity:25g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 09:14
Price ($):233.0

Additional information on 3-Amino-N-(Tertbutylbenzenesulfonamide

Comprehensive Overview of 3-Amino-N-(Tert-Butyl)benzenesulfonamide (CAS No. 608523-94-0)

3-Amino-N-(Tert-Butyl)benzenesulfonamide (CAS No. 608523-94-0) is a specialized organic compound widely recognized for its unique structural properties and versatile applications in pharmaceutical and chemical research. This sulfonamide derivative features a tert-butyl group attached to a benzenesulfonamide backbone, which enhances its stability and reactivity in synthetic pathways. Researchers and industry professionals frequently search for terms like "sulfonamide synthesis", "tert-butyl benzene derivatives", and "CAS 608523-94-0 applications", reflecting its relevance in modern chemistry.

The compound’s molecular structure, characterized by the amino group at the 3-position of the benzene ring, enables it to participate in diverse reactions, including coupling and substitution processes. Recent trends in green chemistry and sustainable synthesis have spurred interest in optimizing its production methods to minimize environmental impact. Queries such as "eco-friendly sulfonamide preparation" and "3-Amino-N-(Tert-Butyl)benzenesulfonamide solubility" highlight the growing demand for efficient and cleaner synthetic routes.

In pharmaceutical contexts, 3-Amino-N-(Tert-Butyl)benzenesulfonamide serves as a key intermediate in the development of bioactive molecules. Its role in drug discovery is underscored by its ability to modulate enzyme activity and interact with biological targets. Popular search terms like "sulfonamide drug intermediates" and "CAS 608523-94-0 in medicinal chemistry" align with its prominence in this field. Additionally, its compatibility with high-throughput screening techniques makes it valuable for identifying novel therapeutic agents.

From an industrial perspective, the compound’s stability under varying pH conditions and thermal resistance make it suitable for applications in material science and catalysis. Researchers often explore its potential in polymer modification and surface coating technologies, as evidenced by searches for "sulfonamide-based polymers" and "tert-butyl benzene catalysts". Its low toxicity profile further broadens its utility in consumer-friendly formulations.

Analytical techniques such as HPLC, NMR, and mass spectrometry are routinely employed to characterize 3-Amino-N-(Tert-Butyl)benzenesulfonamide, ensuring purity and consistency for research and commercial use. FAQs like "how to analyze CAS 608523-94-0" and "sulfonamide spectroscopic data" reflect the need for reliable quality control methods. The compound’s spectral properties are well-documented, aiding in its identification and application validation.

Emerging trends in computational chemistry have also leveraged 3-Amino-N-(Tert-Butyl)benzenesulfonamide as a model for studying molecular interactions and reaction mechanisms. Searches for "molecular docking with sulfonamides" and "DFT studies on benzene derivatives" demonstrate its role in advancing theoretical frameworks. This intersection of experimental and computational approaches underscores its multidisciplinary significance.

In summary, 3-Amino-N-(Tert-Butyl)benzenesulfonamide (CAS No. 608523-94-0) is a multifaceted compound with broad applicability across pharmaceuticals, materials science, and catalysis. Its alignment with contemporary research priorities—such as sustainability, drug development, and advanced analytics—ensures its continued relevance. By addressing common search queries and integrating cutting-edge topics, this overview provides a robust, SEO-optimized resource for professionals and enthusiasts alike.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:608523-94-0)3-Amino-N-(Tertbutylbenzenesulfonamide
A868871
Purity:99%
Quantity:25g
Price ($):233.0
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