Cas no 606-68-8 (b-NADH Disodium Salt)
b-NADH Disodium Salt Chemical and Physical Properties
Names and Identifiers
-
- beta-Nicotinamide adenine dinucleotide disodium salt
- beta-NADH disodium salt
- β-NADH
- beta-Nicotinamide Adenine Dinucleotide Disodium Salt Hydrate, reduced form[for Biochemical Research]
- Disodium NADH
- NADH
- NADH (sodium salt)
- Nicotinamide adenine dinucleotide (reduced) disodium salt (NADH 2Na)
- β-NADH Disodium Salt
- β-Nicotinamide adenine dinucleotide disodium salt
- beta-NicotinaMide adenine dinucleotide
- β-DPNH
- Coenzyme I reduced disodium salt
- Diphosphopyridine nucleotide reduced disodium salt
- Coenzyme I Disodium Salt Hydrate, reduced form
- Cozymase Disodium Salt Hydrate, reduced form
- β-Diphosphopyridine Nucleotide Disodium Salt Hydrate, reduced form
- β-DPNH Disodium Salt Hydrate, reduced form
- β-NADH Disodium Salt Hydrate, reduced form
- NADH disodium salt
- Disodium NADH
- Adenosine 5'-(trihydrogen pyrophosphate), 5'→5'-ester with 1,4-dihydro-1-β-D-ribofuranosylnicotinamide, disodium salt (8CI)
- Adenosine 5'-(trihydrogen diphosphate), P'→5'-ester with 1,4-dihydro-1-β-D-ribofuranosyl-3-pyridinecarboxamide, disodium salt (9CI)
- Adenosine 5'-(trihydrogen diphosphate), P'→5'-ester with 1,4-dihydro-1-β-D-ribofuranosylnicotinamide, sodium salt (1:2)
- NADH disodium salt
- Adenosine 5'-(trihydrogen diphosphate), P'→5'-ester with 1,4-dihydro-1-β-D-ribofuranosyl-3-pyridinecarboxamide, disodium salt (9CI)
- Adenosine 5'-(trihydrogen pyrophosphate), 5'→5'-ester with 1,4-dihydro-1-β-D-ribofuranosylnicotinamide, disodium salt (8CI)
- b-NADH Disodium Salt
-
- MDL: MFCD03791273
- Inchi: 1S/C21H29N7O14P2.2Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33;;/h1,3-4,7-8,10-11,13-16,20-21,29-32H,2,5-6H2,(H2,23,33)(H,34,35)(H,36,37)(H2,22,24,25);;/q;2*+1/p-2/t10-,11-,13-,14-,15-,16-,20-,21-;;/m1../s1
- InChI Key: QRGNQKGQENGQSE-WUEGHLCSSA-L
- SMILES: P(=O)([O-])(OP(=O)([O-])OC[C@@H]1[C@H]([C@H]([C@H](N2C=CCC(C(N)=O)=C2)O1)O)O)OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3C(N)=NC=NC2=3)O1)O)O.[Na+].[Na+]
Computed Properties
- Exact Mass: 709.08900
- Monoisotopic Mass: 709.089
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 7
- Hydrogen Bond Acceptor Count: 21
- Heavy Atom Count: 46
- Rotatable Bond Count: 11
- Complexity: 1110
- Covalently-Bonded Unit Count: 3
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 8
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 1
- Tautomer Count: 6
- XLogP3: nothing
- Topological Polar Surface Area: 323A^2
Experimental Properties
- Color/Form: Yellow powder
- Melting Point: 140-142°C
- Boiling Point: Vapour density:
- Flash Point: 608 °C
- PH: 7.5 (100mg/mL in water, ±0.5)
- Solubility: H2O: 50?mg/mL, clear to nearly clear, yellow
- Water Partition Coefficient: dissolution
- Stability/Shelf Life: Stable. Incompatible with strong oxidizing agents.
- PSA: 342.90000
- LogP: -0.59060
- FEMA: 2717
- Solubility: dissolve in water
b-NADH Disodium Salt Security Information
- Hazard Statement: H302-H315-H319-H335
- Hazardous Material transportation number:NONH for all modes of transport
- WGK Germany:3
- Hazard Category Code: 23/24/25-36/37/38-39/23/24/25-40-22
- Safety Instruction: S26; S36/37/39; S45; S24/25; S36/37
- FLUKA BRAND F CODES:3-10-23
-
Hazardous Material Identification:
- TSCA:Yes
- Storage Condition:<0°C
- Risk Phrases:R36/37/38
- Safety Term:S24/25
b-NADH Disodium Salt Customs Data
- HS CODE:2924199090
- Customs Data:
China Customs Code:
2924199090Overview:
2924199090. Other acyclic amides(Including acyclic carbamates)(Including its derivatives and salts). VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%
Declaration elements:
Product Name, component content, use to, packing
Summary:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
b-NADH Disodium Salt Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | A-CH818-1g |
b-NADH Disodium Salt |
606-68-8 | 98% | 1g |
387.0CNY | 2021-08-06 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | A-CH818-200mg |
b-NADH Disodium Salt |
606-68-8 | 98% | 200mg |
122.0CNY | 2021-08-06 | |
| TI XI AI ( SHANG HAI ) HUA CHENG GONG YE FA ZHAN Co., Ltd. | D0920-1G |
β-Nicotinamide Adenine Dinucleotide Disodium Salt, reduced form [for Biochemical Research] |
606-68-8 | 1g |
¥1040.00 | 2024-04-16 | ||
| HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI | H004642-1g |
b-NADH Disodium Salt |
606-68-8 | ≥98% | 1g |
¥320元 | 2023-09-15 | |
| HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI | H004642-250mg |
b-NADH Disodium Salt |
606-68-8 | ≥98% | 250mg |
¥100元 | 2023-09-15 | |
| HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI | H004642-5g |
b-NADH Disodium Salt |
606-68-8 | ≥98% | 5g |
¥1320元 | 2023-09-15 | |
| HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI | FN3950-1g |
b-NADH Disodium Salt |
606-68-8 | ≥98% | 1g |
¥150元 | 2023-09-15 | |
| HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI | FN3950-25g |
b-NADH Disodium Salt |
606-68-8 | ≥98% | 25g |
¥1950元 | 2023-09-15 | |
| HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI | FN3950-5g |
b-NADH Disodium Salt |
606-68-8 | ≥98% | 5g |
¥450元 | 2023-09-15 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R015279-1g |
b-NADH Disodium Salt |
606-68-8 | 98% | 1g |
¥240 | 2023-09-08 |
b-NADH Disodium Salt Suppliers
b-NADH Disodium Salt Related Literature
-
A. B. F. da Silva,K. Capelle Phys. Chem. Chem. Phys., 2009,11, 4564-4569
-
Jonas Kind,Lukas Kaltschnee,Martin Leyendecker,Christina M. Thiele Chem. Commun., 2016,52, 12506-12509
-
3. Estimating and correcting interference fringes in infrared spectra in infrared hyperspectral imagingGhazal Azarfar,Ebrahim Aboualizadeh,Nicholas M. Walter,Simona Ratti,Camilla Olivieri,Alessandra Norici,Michael Nasse,Achim Kohler,Mario Giordano Analyst, 2018,143, 4674-4683
-
Dan Yang,Yanping Zhou,Xianhong Rui,Jixin Zhu,Ziyang Lu,Eileen Fong,Qingyu Yan RSC Adv., 2013,3, 14960-14962
-
Shun-Ze Zhan,Mian Li,Xiao-Ping Zhou,Dan Li,Seik Weng Ng RSC Adv., 2011,1, 1457-1459
Additional information on b-NADH Disodium Salt
b-NADH Disodium Salt (CAS No: 606-68-8) in Modern Biochemical Research and Therapeutic Applications
The compound b-NADH Disodium Salt, identified by the Chemical Abstracts Service Number (CAS No) 606-68-8, is a critical cofactor in numerous biochemical processes, playing a pivotal role in cellular energy metabolism. This compound, chemically known as sodium salt of β-nicotinamide adenine dinucleotide reduced form, is widely utilized in both academic research and industrial applications due to its unique properties and versatility. Thedisodium salt formulation enhances its solubility and stability, making it an ideal candidate for various biochemical assays and therapeutic interventions.
In recent years, the significance of b-NADH Disodium Salt has been underscored by its involvement in cutting-edge research aimed at understanding and mitigating age-related decline. Nicotinamide adenine dinucleotide (NAD+) is a vital coenzyme found in all living cells, participating in redox reactions and serving as a substrate for enzymes involved in energy production. The reduced form, NADH, is particularly crucial for maintaining cellular homeostasis. Studies have demonstrated that NADH levels decline with age, contributing to mitochondrial dysfunction and oxidative stress. This has spurred interest in the development of strategies to replenish NAD+ pools, with b-NADH Disodium Salt emerging as a promising tool.
Thedisodium salt form of NADH offers several advantages over other formulations. Its enhanced solubility in aqueous solutions facilitates easier incorporation into experimental systems, while its stability under various conditions ensures reliable results. These properties make it an invaluable resource for researchers studying metabolic pathways, mitochondrial health, and neuroprotective mechanisms. Furthermore, the use of b-NADH Disodium Salt has been explored in preclinical models investigating the potential benefits of NADH supplementation in combating neurodegenerative disorders such as Alzheimer's disease and Parkinson's disease.
Recent advancements in biotechnology have enabled the development of novel delivery systems for b-NADH Disodium Salt, enhancing its bioavailability and therapeutic efficacy. Liposomal encapsulation and nanotechnology-based approaches have shown promise in delivering NADH directly to target tissues, thereby optimizing its pharmacological effects. These innovations are particularly relevant in the context of treating chronic diseases where sustained intracellular levels of NAD+ are essential.
The role of b-NADH Disodium Salt extends beyond basic research; it has significant implications for therapeutic applications. In the field of anti-aging medicine, NADH supplementation has been proposed as a means to counteract age-related decline by restoring mitochondrial function and reducing oxidative damage. Clinical trials are ongoing to evaluate the efficacy of NADH-based therapies in improving cognitive function, muscle performance, and overall vitality. Additionally, the compound has been investigated for its potential role in managing metabolic disorders such as diabetes and obesity by enhancing insulin sensitivity and energy expenditure.
Thedisodium salt formulation of b-NADH offers distinct advantages over other forms due to its superior solubility and stability. These characteristics make it an ideal candidate for use in high-throughput screening assays and large-scale biochemical studies. Researchers have leveraged these properties to develop novel enzymatic assays and redox-based sensors that rely on precise concentrations of NADH for accurate measurements. Such tools are essential for unraveling complex biological pathways and identifying new drug targets.
In conclusion, b-NADH Disodium Salt (CAS No: 606-68-8) represents a cornerstone compound in modern biochemical research and therapeutic development. Its multifaceted roles in energy metabolism, cellular signaling, and disease mitigation underscore its importance as a research tool and potential therapeutic agent. As our understanding of NAD+ biology continues to evolve, the applications of thisdisodium salt formulation are expected to expand further, opening new avenues for treating a wide range of health conditions.
606-68-8 (b-NADH Disodium Salt) Related Products
- 146-78-1(2-Fluoroadenosine)
- 53-59-8(NADP)
- 60-92-4(Cyclic AMP)
- 86-08-8(3-Acetylpyridine adenine dinucleotide)
- 68141-45-7(b-Nicotinamide adenine dinucleotide phosphate potassium salt hydrate)
- 56-65-5(Adenosine 5'-Triphosphate)
- 61-19-8(Adenosine monophosphate)
- 53-84-9(b-Nicotinamide Adenine Dinucleotide)
- 58-61-7(Adenosine)
- 7298-93-3(β-D-Xylofuranose, 1-(6-amino-9H-purin-9-yl)-1-deoxy-, inner salt, 5-[3-(aminocarbonyl)-1-[5-O-[hydroxy(phosphonooxy)phosphinyl]-α-D-ribofuranosyl]pyridiniumyl])