Cas no 60545-29-1 (Butanoyl chloride, 2-ethyl-2-methyl-)

Butanoyl chloride, 2-ethyl-2-methyl-, is a branched-chain acyl chloride with the molecular formula C?H??ClO. This compound is characterized by its sterically hindered structure, which influences its reactivity in acylation reactions. The presence of ethyl and methyl substituents at the α-carbon enhances selectivity in synthetic applications, making it useful for producing specialized esters, amides, and other derivatives. Its reactivity is moderated compared to linear acyl chlorides, reducing side reactions in sensitive transformations. The compound is typically employed in fine chemical synthesis and pharmaceutical intermediates, where controlled acylations are required. Proper handling is essential due to its moisture sensitivity and corrosive nature.
Butanoyl chloride, 2-ethyl-2-methyl- structure
60545-29-1 structure
Product Name:Butanoyl chloride, 2-ethyl-2-methyl-
CAS No:60545-29-1
MF:C7H13ClO
MW:148.630521535873
CID:497077
Update Time:2026-04-29

Butanoyl chloride, 2-ethyl-2-methyl- Chemical and Physical Properties

Names and Identifiers

    • Butanoyl chloride, 2-ethyl-2-methyl-
    • 2-ethyl-2-methylbutanoyl chloride

Computed Properties

  • Exact Mass: 148.06559

Experimental Properties

  • PSA: 17.07

Butanoyl chloride, 2-ethyl-2-methyl- Pricemore >>

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Butanoyl chloride, 2-ethyl-2-methyl- Related Literature

Additional information on Butanoyl chloride, 2-ethyl-2-methyl-

Butanoyl Chloride, 2-Ethyl-2-Methyl-

Butanoyl chloride, 2-ethyl-2-methyl- (CAS No. 60545-29-1) is a versatile organic compound with significant applications in various industries. This compound is a member of the aliphatic acid chlorides family and is characterized by its unique chemical structure and reactivity. The molecule consists of a butanoyl group attached to a chloride ion, with branching at the second carbon atom, giving it the name 2-ethyl-2-methylbutanoyl chloride.

Butanoyl chloride, 2-ethyl-2-methyl-, CAS No. 60545-29-1, is widely used in the synthesis of esters, amides, and other derivatives due to its reactivity with alcohols and amines. Its ability to form stable derivatives makes it an essential intermediate in the production of pharmaceuticals, agrochemicals, and specialty chemicals. Recent studies have highlighted its role in the development of biodegradable polymers, where it serves as a building block for eco-friendly materials.

The synthesis of butanoyl chloride, 2-ethyl-2-methyl-, CAS No. 60545-29-1, typically involves the reaction of the corresponding carboxylic acid with thionyl chloride (SOCl?) or phosphorus trichloride (PCl?). This process generates hydrogen chloride (HCl) as a byproduct, which can be neutralized or recycled. The compound is usually obtained as a colorless liquid with a characteristic odor, and it is highly reactive due to the electrophilic nature of the carbonyl carbon.

One of the most notable applications of butanoyl chloride, 2-ethyl-2-methyl-, CAS No. 60545-29-1, is in the fragrance industry. It is used as an intermediate in the synthesis of esters that impart floral and woody notes to perfumes and cosmetics. For instance, its derivative, isobutyl butyrate, is commonly used in perfumery for its pleasant aroma.

Recent advancements in green chemistry have led to the exploration of more sustainable methods for synthesizing butanoyl chloride, 2-ethyl-2-methyl-, CAS No. 60545-29. Researchers have focused on developing catalysts that minimize the use of hazardous reagents and reduce environmental impact. For example, microwave-assisted synthesis has been shown to enhance reaction efficiency while reducing energy consumption.

In addition to its industrial applications, butanoyl chloride, 2-ethyl-2-methyl-, CAS No. 60545, has gained attention in academic research for its potential in drug delivery systems. Its ability to form amphiphilic molecules makes it a promising candidate for encapsulating hydrophobic drugs. Studies have demonstrated that derivatives of this compound can enhance drug solubility and bioavailability.

The global market for butanoyl chloride, 2-Ethyl - , CAS No. 60545, has seen steady growth due to increasing demand from pharmaceuticals and specialty chemicals sectors. According to recent market analyses, emerging economies are driving this growth as they expand their manufacturing capabilities in fine chemicals.

In terms of safety considerations, handling butanoyl chloride (CAS No. 60545) requires appropriate personal protective equipment (PPE) due to its irritant properties. Proper ventilation and storage are essential to prevent exposure risks.

Looking ahead, butanoyl chloride (CAS No.) will likely play an even more critical role in sustainable chemistry as researchers continue to explore novel applications and greener synthesis routes.

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