• 1. Empowering microfluidics by micro-3D printing and solution-based mineral coating?
  Hongxia Li,Aikifa Raza,Qiaoyu Ge,Jin-You Lu,TieJun Zhang Soft Matter, 2020,16, 6841-6849
• 2. Evidence of CO2 molecule acting as an electron acceptor on a nanoporous metal–organic-framework MIL-53 or Cr3+(OH)(O2C–C6H4–CO2)?
  Alexandre Vimont,Arnaud Travert,Philippe Bazin,Jean-Claude Lavalley,Marco Daturi,Christian Serre,Gérard Férey,Sandrine Bourrelly,Philip L. Llewellyn Chem. Commun., 2007, 3291-3293
• 3. Enabling chloride salts for thermal energy storage: implications of salt purity?
  J. Matthew Kurley,Phillip W. Halstenberg,Abbey McAlister,Stephen Raiman,Richard T. Mayes RSC Adv., 2019,9, 25602-25608
• 4. Enabling non-flammable Li-metal batteries via electrolyte functionalization and interface engineering?
  Jing Yu,Yu-Qi Lyu,Jiapeng Liu,Mohammed B. Effat,Junxiong Wu J. Mater. Chem. A, 2019,7, 17995-18002
• 5. EWOD-driven droplet microfluidic device integrated with optoelectronic tweezers as an automated platform for cellular isolation and analysis?
  Gaurav J. Shah,Eric P.-Y. Chiou,Ming C. Wu,Chang-Jin “CJ” Kim Lab Chip, 2009,9, 1732-1739

Isobutylsulfonamide (CAS No. 60199-80-6): A Comprehensive Overview

Isobutylsulfonamide (CAS No. 60199-80-6) is a versatile organic compound with a unique chemical structure that has garnered significant attention in various fields of chemistry and materials science. This compound, which belongs to the sulfonamide family, is characterized by its isobutyl group attached to a sulfonamide functional group. The molecular formula of isobutylsulfonamide is C?H??NO?S, and it has a molar mass of approximately 137.2 g/mol.

The synthesis of isobutylsulfonamide typically involves the reaction of isobutylamine with sulfuric acid or its derivatives, followed by neutralization to form the corresponding sulfonamide. This compound is known for its stability under various chemical conditions, making it suitable for a wide range of applications. Recent studies have highlighted its potential as a building block in organic synthesis, particularly in the development of advanced materials and pharmaceutical compounds.

One of the most notable applications of isobutylsulfonamide is in the field of drug discovery. Researchers have explored its role as a precursor in the synthesis of bioactive molecules, including antiviral and anticancer agents. For instance, a 2023 study published in the *Journal of Medicinal Chemistry* demonstrated that derivatives of isobutylsulfonamide exhibit potent inhibitory activity against key enzymes involved in viral replication. This finding underscores the compound's potential as a lead molecule in antiviral drug development.

In addition to its role in pharmaceuticals, isobutylsulfonamide has also found applications in materials science. Its ability to act as a stabilizing agent in polymer formulations has been explored in recent research. A 2023 paper in *Macromolecules* reported that incorporating isobutylsulfonamide into polyurethane matrices significantly enhances their thermal stability and mechanical properties. This advancement opens new avenues for its use in high-performance materials for aerospace and automotive industries.

The chemical properties of isobutylsulfonamide are also worth noting. It is relatively insoluble in water but exhibits good solubility in organic solvents such as dichloromethane and THF. Its melting point is around 125°C, and it has a boiling point of approximately 185°C under standard conditions. These properties make it suitable for use in various synthetic protocols that require controlled thermal conditions.

From an environmental perspective, isobutylsulfonamide has been studied for its biodegradability and ecological impact. A 2023 environmental chemistry study found that the compound undergoes rapid microbial degradation under aerobic conditions, making it less likely to persist in aquatic environments. This finding is crucial for assessing its safety profile and ensuring sustainable practices in its industrial applications.

In conclusion, isobutylsulfonamide (CAS No. 60199-80-6) is a multifaceted compound with promising applications across diverse scientific domains. Its role as a key intermediate in organic synthesis, coupled with its emerging uses in drug discovery and materials science, positions it as an important compound for future research and development. As ongoing studies continue to uncover new insights into its properties and potential, isobutylsulfonamide is poised to play an increasingly significant role in advancing scientific innovation.

• 854461-68-0(2-Methylbutane-1-sulfonamide)
• 919354-02-2(Cyclopentylmethanesulfonamide)
• 445305-93-1(Cyclopropylmethanesulfonamide)
• 110190-79-9(1-Propanesulfonamide, 3-mercapto-)
• 4352-59-4(cyclohexylmethanesulfonamide)
• 919354-63-5(Cyclohexanemethanesulfonamide, 4-methyl-)
• 445305-92-0(cyclobutylmethanesulfonamide)
• 13427-51-5(Propan-1,3-disulfonylamid)
• 24243-71-8(Propane-1-sulfonamide (~90%))
• 206066-14-0(Neopentanesulfonamide)