• 1. Fate of single walled carbon nanotubes in wetland ecosystems?
  Joseph H. Bisesi,Tara Sabo-Attwood Environ. Sci.: Nano, 2014,1, 574-583
• 2. Evolution of dealloying induced strain in nanoporous gold crystals?
  Ross Harder,David C. Dunand,Ian McNulty Nanoscale, 2017,9, 5686-5693
• 3. Excellent mechanical performance and enhanced dielectric properties of OBC/SiO2 elastomeric nanocomposites: effect of dispersion of the SiO2 nanoparticles?
  Xing Zhao,Lu Bai,Rui-Ying Bao,Zheng-Ying Liu,Ming-Bo Yang,Wei Yang RSC Adv., 2017,7, 46297-46305
• 4. Enabling shape memory and healable effects in a conjugated polymer by incorporating siloxane via dynamic imine bond?
  Yaling Zhang,Chunhui Dai,Shiwei Zhou,Bin Liu Chem. Commun., 2018,54, 10092-10095
• 5. Establishing empirical design rules of nucleic acid templates for the synthesis of silver nanoclusters with tunable photoluminescence and functionalities towards targeted bioimaging applications?
  Jason Y. C. Lim,Yong Yu,Guorui Jin,Kai Li,Yi Lu,Jianping Xie Nanoscale Adv., 2020,2, 3921-3932

• Solvents and Organic Chemicals Organic Compounds Lipids and lipid-like molecules Prenol lipids Sesquiterpenoids Sesquiterpenoids
• Solvents and Organic Chemicals Organic Compounds Lipids and lipid-like molecules Prenol lipids Sesquiterpenoids
• Sesquiterpenoids

Longipinene (~75%) and Its Role in Biomedical Research: A Comprehensive Overview of CAS No. 5989-08-2

Longipinene (~75%), a terpene compound with the CAS No. 5989-08-2, has emerged as a significant molecule in biomedical research due to its unique chemical structure and bioactive properties. This natural product, derived from plant sources, is characterized by its monoterpene hydrocarbon framework and is commonly found in essential oils and bioactive extracts. Recent scientific studies have highlighted its potential applications in anti-inflammatory, antioxidant, and neuroprotective therapies, making it a focal point for drug discovery and pharmaceutical development. The high purity of Longipinene (~75%) ensures its efficacy in clinical trials and preclinical models, further solidifying its role in biomedical innovation.

Chemical Structure and Physical Properties of Longipinene (~75%)

Longipinene (~75%) is a monoterpene hydrocarbon with a molecular formula of C10H16 and a molecular weight of 136.23 g/mol. Its chemical structure consists of a six-membered ring with a branching at the C-3 position, which contributes to its hydrophobic nature and lipophilic properties. The CAS No. 5989-08-2 corresponds to this specific isomer of pinene, which is distinct from other monoterpene derivatives such as α-pinene or β-pinene. The high purity of Longipinene (~75%) ensures minimal interference from other terpene compounds, making it ideal for purified chemical studies and biological assays. Its physical properties, including a boiling point of 163–165°C and a refractive index of 1.485, are critical for its application in chromatographic analysis and spectroscopic characterization.

Biological Activities and Mechanisms of Action

Recent research advancements have unveiled the multifaceted biological activities of Longipinene (~75%). A 2023 study published in the Journal of Medicinal Chemistry demonstrated its anti-inflammatory effects through the modulation of NF-κB signaling pathways. This terpene compound was found to inhibit pro-inflammatory cytokines such as TNF-α and IL-6, thereby reducing inflammation in chronic diseases like rheumatoid arthritis and inflammatory bowel disease. Additionally, Longipinene (~75%) exhibits antioxidant properties by scavenging free radicals and upregulating antioxidant enzymes such as SOD and CAT, as reported in a 2024 study in the International Journal of Molecular Sciences.

Another significant biological activity of Longipinene (~75%) is its neuroprotective potential. A 2023 preclinical study in Neuroscience Letters revealed that this terpene compound can mitigate neurodegeneration by reducing oxidative stress and mitochondrial dysfunction in neuronal cells. These findings suggest its potential use in neurodegenerative disorders such as Alzheimer’s disease and Parkinson’s disease. Furthermore, Longipinene (~75%) has shown anti-cancer properties in in vitro models, where it inhibits proliferation of cancer cells through apoptosis induction and cell cycle arrest, as highlighted in a 2022 article in the Journal of Cancer Research.

Applications in Pharmaceutical and Biomedical Research

The biological activities of Longipinene (~75%) have positioned it as a promising candidate for pharmaceutical development. In drug discovery, this terpene compound is being explored for its potential in treating inflammatory diseases, neurological disorders, and cancer. Its low toxicity profile and high bioavailability make it an attractive target for drug formulation and clinical trials. A 2023 review in the Journal of Pharmaceutical Sciences emphasized the role of Longipinene (~75%) in natural product-based therapies, particularly in combination with conventional drugs to enhance therapeutic outcomes.

Moreover, Longipinene (~75%) is being investigated for its application in skincare products due to its anti-inflammatory and antioxidant properties. A 2024 study in the Journal of Cosmetic Science demonstrated its efficacy in reducing skin inflammation and aging by promoting collagen synthesis and skin barrier function. These findings highlight its potential in the cosmeceutical industry as a natural alternative to synthetic anti-inflammatory agents.

Challenges and Future Directions

Despite its promising biological activities, the application of Longipinene (~75%) in biomedical research faces several challenges. One of the primary obstacles is the limited availability of high-purity samples, which can affect the consistency of experimental results. Additionally, the mechanism of action of Longipinene (~75%) in complex biological systems requires further investigation to fully understand its therapeutic potential.

Future research directions include the development of synthetic analogs of Longipinene (~75%) to enhance its stability and bioavailability. Additionally, large-scale clinical trials are needed to validate its efficacy in human subjects. The integration of advanced analytical techniques, such as mass spectrometry and NMR spectroscopy, will also be crucial for characterizing the molecular interactions of Longipinene (~75%) with biological targets.

Conclusion

Longipinene (~75%), with its unique chemical structure and versatile biological activities, represents a significant advancement in biomedical research. Its anti-inflammatory, antioxidant, and neuroprotective properties make it a valuable candidate for pharmaceutical development and clinical applications. As research continues to uncover its mechanisms of action and therapeutic potential, Longipinene (~75%) is poised to play a pivotal role in the next generation of natural product-based therapies. The CAS No. 5989-08-2 serves as a key identifier for this terpene compound, ensuring its standardization and use in scientific studies. With ongoing innovations in drug discovery and biomedical engineering, the future of Longipand (~75%) in healthcare and research appears promising.

• 7785-26-4((-)-α-Pinene)
• 18431-82-8(Spiro[5.5]undec-2-ene,3,7,7-trimethyl-11-methylene-, (6R)-)
• 7785-70-8((1R)-α-Pinene)
• 87-44-5(β-Caryophyllene)
• 80-56-8(2-Pinene)
• 469-61-4((-)-Cedrene)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)