• 1. Copper(ii) complexes with 2-ethylpyridine and related hydroxyl pyridine derivatives: structural, spectroscopic, magnetic and anticancer in vitro studies
  Magdalena Malik,Anna ?witlicka,Alina Bieńko,Urszula K. Komarnicka,Dariusz C. Bieńko,Sandra Kozie?,Agnieszka Kyzio?,Tomasz Mazur,Barbara Machura RSC Adv. 2022 12 27648
• 2. The cooperative effect of Lewis pairs in the Friedel–Crafts hydroxyalkylation reaction: a simple and effective route for the synthesis of (±)-carbinoxamine
  Adhikesavan Harikrishnan,Jayakumar Sanjeevi,Chinnasamy Ramaraj Ramanathan Org. Biomol. Chem. 2015 13 3633
• 3. Preparation of the Ru3(CO)8-pyridine-alcohol cluster and its use for the selective catalytic transformation of primary to secondary amines
  Ajeet Singh,Shaikh M. Mobin,Pradeep Mathur Dalton Trans. 2018 47 14033
• 4. Nuclearity growth towards Ni(ii) cubane in self-assembly with 2-hydroxymethyl pyridine (hmpH) and 5-ethoxycarbonyl-2-hydroxymethyl pyridine (5-ehmpH)
  Wen-Hua Zhang,Norlela Binte Sulaiman,P. X. Shaun Tio,T. S. Andy Hor CrystEngComm 2011 13 2915
• 5. Direct intermolecular C–H arylation of unactivated arenes with aryl bromides catalysed by 2-pyridyl carbinol
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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Pyridines and derivatives
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives

Professional Introduction to 2-Pyridinemethanol (CAS No. 586-98-1)

2-Pyridinemethanol, with the chemical formula C?H?NO, is a significant compound in the field of pharmaceutical and biochemical research. This heterocyclic alcohol, identified by its CAS number 586-98-1, has garnered considerable attention due to its versatile applications and structural properties. The compound belongs to the pyridine family, characterized by a nitrogen-containing aromatic ring, which makes it a valuable scaffold for drug development and synthetic chemistry.

The< strong>2-Pyridinemethanol molecule exhibits a unique combination of functional groups, including a hydroxyl group and a pyridine ring, which contribute to its reactivity and biological activity. These features have made it a popular intermediate in the synthesis of various pharmacologically active molecules. Recent studies have highlighted its role in developing novel therapeutic agents targeting neurological disorders, infectious diseases, and metabolic conditions.

In the realm of medicinal chemistry, 2-Pyridinemethanol has been extensively explored for its potential as a precursor in the synthesis of bioactive compounds. Its structural motif is frequently incorporated into drug candidates due to its ability to interact with biological targets effectively. For instance, derivatives of 2-Pyridinemethanol have shown promise in inhibiting enzymes involved in cancer progression and inflammation. The< strong>CAS no. 586-98-1 identifier ensures precise identification and regulatory compliance, facilitating its use in both academic and industrial research settings.

Recent advancements in computational chemistry have further enhanced the understanding of 2-Pyridinemethanol's interactions with biological systems. Molecular docking studies have revealed that this compound can bind to specific protein targets with high affinity, suggesting its potential as an anti-inflammatory agent. Additionally, spectroscopic techniques such as NMR and mass spectrometry have been employed to elucidate its structural properties, providing insights into its behavior in different chemical environments.

The< strong>pyridine ring present in 2-Pyridinemethanol is particularly noteworthy for its ability to modulate biological activity through various mechanisms. This moiety is commonly found in many drugs due to its capacity to form hydrogen bonds and participate in hydrophobic interactions with biological targets. Researchers have leveraged these properties to design molecules with enhanced pharmacological efficacy and reduced side effects. The< strong>hydroxyl group on the other hand, contributes to the compound's solubility and reactivity, making it a versatile building block for further chemical modifications.

In clinical research, 2-Pyridinemethanol has been investigated for its potential therapeutic applications. Preclinical studies have demonstrated its efficacy in models of neurodegenerative diseases, where it acts as a modulator of neurotransmitter pathways. Furthermore, its antimicrobial properties have been explored, with some derivatives showing activity against resistant bacterial strains. These findings underscore the compound's significance as a lead molecule for drug discovery efforts.

The synthesis of< strong>2-Pyridinemethanol can be achieved through multiple routes, each offering distinct advantages depending on the desired scale and purity requirements. Common methods include reduction of corresponding pyridine nitriles or condensation reactions involving appropriate precursors. Advances in synthetic methodologies have enabled more efficient and sustainable production processes, aligning with global trends toward green chemistry principles.

The< strong>CAS no. 586-98-1 classification ensures that researchers can reliably source and handle this compound while adhering to safety protocols. Its stability under various storage conditions makes it suitable for long-term projects and large-scale preparations. Moreover, regulatory agencies recognize the importance of precise identification through CAS numbers, which helps prevent contamination and ensures reproducibility across different laboratories.

In conclusion, 2-Pyridinemethanol(CAS No. 586-98-1) represents a valuable asset in pharmaceutical research due to its structural versatility and biological activity. The ongoing exploration of this compound continues to yield promising results for developing novel therapeutics across multiple disease areas. As scientific understanding progresses, the applications of< strong>2-Pyridinemethanol are expected to expand further, solidifying its role as a cornerstone in modern drug discovery.

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