Direct intermolecular C–H arylation of unactivated arenes with aryl bromides catalysed by 2-pyridyl carbinol?
Organic & Biomolecular Chemistry Pub Date: 2014-07-23 DOI: 10.1039/C4OB01211A
Abstract
Direct intermolecular C–H arylation employing aryl bromide as the arene source has been developed. This process proceeds via a simple transition-metal-free pathway. With the aid of inexpensive and commercially available 2-pyridyl carbinol and potassium tert-butoxide, various unactivated arene C–H bonds can be directly arylated by aryl bromides through homolytic aromatic substitution.
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Journal Name：Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4
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