Production Method 1

461-58-5

503-29-7

109-76-2

5807-14-7

108-78-1

Reaction Conditions

1.1160°C
2.12 h, 200°C

Reference

Method for synthesizing bicyclic guanidine

By Cui, Zhaoshan et al, Faming Zhuanli Shenqing, From Faming Zhuanli Shenqing, 112094273, 18 Dec 2020, 112094273, 18 Dec 2020

Triazabicyclodecene Raw materials

• Dicyandiamide
• Azetidine
• 1,3-Diaminopropan

Triazabicyclodecene Preparation Products

• Triazabicyclodecene (5807-14-7)
• Melamine (108-78-1)

• 1. Fe/Fe3C@C nanoparticles encapsulated in N-doped graphene–CNTs framework as an efficient bifunctional oxygen electrocatalyst for robust rechargeable Zn–air batteries?
  Zhiyan Chen,Nan Wu,Yaobing Wang,Bing Wang,Yingde Wang J. Mater. Chem. A, 2018,6, 516-526
• 2. Fe3O4 nanosphere@microporous organic networks: enhanced anode performances in lithium ion batteries through carbonization?
  Byungho Lim,Jaewon Jin,Jin Yoo,Seung Yong Han,Kyeongyeol Kim,Sungah Kang,Nojin Park,Sang Moon Lee,Hae Jin Kim,Seung Uk Son Chem. Commun., 2014,50, 7723-7726
• 3. Excellent lithium ion storage property of porous MnCo2O4 nanorods?
  Peiyuan Zeng,Xiaoxiao Wang,Ming Ye,Qiuyang Ma,Jianwen Li,Wanwan Wang,Baoyou Geng,Zhen Fang RSC Adv., 2016,6, 23074-23084
• 4. Establishing new scaling relations on two-dimensional MXenes for CO2 electroreduction?
  Albertus D. Handoko,Khoong Hong Khoo,Teck Leong Tan,Hongmei Jin,Zhi Wei Seh J. Mater. Chem. A, 2018,6, 21885-21890
• 5. Evidence that the availability of an allylic hydrogen governs the regioselectivity of the Wacker oxidation
  Matthew J. Gaunt,Jinquan Yu,Jonathan B. Spencer Chem. Commun., 2001, 1844-1845

• Solvents and Organic Chemicals Organic Compounds Heterocyclic Compounds
• Solvents and Organic Chemicals Organic Compounds

Introduction to Triazabicyclodecene (CAS No. 5807-14-7)

Triazabicyclodecene, a compound with the chemical formula C₁₀H₉N₃, is a highly intriguing molecule that has garnered significant attention in the field of chemical and pharmaceutical research. The compound is identified by its unique CAS number, CAS No. 5807-14-7, which distinguishes it in the vast repository of chemical substances. This introduction aims to provide a comprehensive overview of Triazabicyclodecene, delving into its structural characteristics, potential applications, and the latest research findings that underscore its significance.

The molecular structure of Triazabicyclodecene consists of a bicyclic framework fused with three nitrogen atoms, forming a triazole ring system. This structural motif imparts unique electronic and steric properties to the molecule, making it a versatile scaffold for various chemical modifications. The presence of multiple reactive sites allows for the synthesis of derivatives that can exhibit diverse biological activities. Such structural features have positioned Triazabicyclodecene as a subject of intense study in medicinal chemistry.

In recent years, the pharmaceutical industry has shown increasing interest in heterocyclic compounds due to their potential therapeutic benefits. Triazabicyclodecene, with its triazole core, has been explored as a key intermediate in the development of novel drugs targeting various diseases. Its ability to interact with biological targets at multiple levels makes it an attractive candidate for drug design. Researchers have been particularly keen on understanding how modifications to the triazole ring can enhance binding affinity and selectivity, thereby improving drug efficacy.

One of the most promising applications of Triazabicyclodecene lies in its role as a precursor for antiviral and anticancer agents. The compound's unique structure allows for the incorporation of pharmacophores that can disrupt viral replication or inhibit cancer cell proliferation. For instance, studies have demonstrated that certain derivatives of Triazabicyclodecene exhibit potent antiviral activity against RNA viruses by interfering with their replication cycle. Similarly, in oncology research, modifications to the molecule have led to the discovery of compounds that selectively target cancer cells without harming healthy tissues.

The synthesis of Triazabicyclodecene presents both challenges and opportunities for chemists. The construction of the bicyclic system while maintaining the integrity of the triazole ring requires precise synthetic strategies. Advances in organic synthesis have enabled more efficient routes to this compound, including catalytic methods that minimize byproduct formation. These improvements have not only made the production of Triazabicyclodecene more feasible but also more sustainable.

Recent research has also highlighted the importance of computational methods in understanding the behavior of Triazabicyclodecene and its derivatives. Molecular modeling techniques have been employed to predict how different structural modifications will affect biological activity. These simulations provide valuable insights into the molecular interactions that underpin drug efficacy, guiding experimental efforts toward more effective candidates.

The environmental impact of synthesizing and using Triazabicyclodecene is another area of growing interest. Efforts are underway to develop greener synthetic routes that reduce waste and energy consumption. Additionally, researchers are exploring ways to optimize the compound's biodegradability to minimize environmental persistence. Such initiatives align with broader trends in sustainable chemistry, where reducing the ecological footprint of chemical processes is paramount.

As our understanding of Triazabicyclodecene continues to evolve, so does its potential in addressing global health challenges. The compound's versatility as a scaffold for drug development makes it a cornerstone in modern medicinal chemistry. By leveraging cutting-edge synthetic methodologies and computational tools, scientists are paving the way for new treatments that could benefit millions worldwide.

In conclusion, Triazabicyclodecene (CAS No. 5807-14-7) represents a fascinating molecule with far-reaching implications in pharmaceutical research. Its unique structure and reactivity make it a valuable asset in developing novel therapeutics for infectious diseases and cancer. As research progresses, we can expect even more innovative applications to emerge from this versatile compound.

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