2933110000 Dimethyl phenyl pyrazolone and its derivatives [dimethyl phenyl pyrazolone i.e. antipyrine].Regulatory conditions:nothing.VAT:17.0%.Tax refund rate:9.0%.Minimum tariff:6.5%.general tariff:20.0%
Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date
2933110000 1,5-dimethyl-2-phenyl-1h-pyrazol-3(2h)-one.Supervision conditions:None.VAT:17.0%.Tax rebate rate:9.0% General tariff:20.0%
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | A116R-500g |
4-Dimethylamino Antipyrine |
58-15-1 | 98% | 500g |
￥219.0 | 2022-05-30 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | A116R-100g |
4-Dimethylamino Antipyrine |
58-15-1 | 98% | 100g |
￥75.0 | 2022-05-30 | |
| YUN NAN XI LI SHENG WU JI SHU GU FEN Co., Ltd. | BBP81214-5mg |
Aminophenazone |
58-15-1 | 98.0% | 5mg |
￥120 | 2021-05-07 | |
| HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI | AA0745-100g |
4-Dimethylamino Antipyrine |
58-15-1 | ≥98% | 100g |
￥90元 | 2023-09-15 | |
| HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI | AA0745-25g |
4-Dimethylamino Antipyrine |
58-15-1 | ≥98% | 25g |
￥40元 | 2023-09-15 | |
| HE FEI BO MEI SHENG WU KE JI YOU XIAN ZE REN GONG SI | AA0745-500g |
4-Dimethylamino Antipyrine |
58-15-1 | ≥98% | 500g |
￥350元 | 2023-09-15 | |
| DC Chemicals | DCAPI1263-100 mg |
Amidopyrine |
58-15-1 | >99% | 100mg |
$250.0 | 2022-03-01 | |
| DC Chemicals | DCAPI1263-250 mg |
Amidopyrine |
58-15-1 | >99% | 250mg |
$500.0 | 2022-03-01 | |
| DC Chemicals | DCAPI1263-1 g |
Amidopyrine |
58-15-1 | >99% | 1g |
$1000.0 | 2022-03-01 | |
| A FA AI SHA ， SAI MO FEI SHI ER KE JI QI XIA GONG SI | B21436-50g |
4-(Dimethylamino)antipyrine, 98+% |
58-15-1 | 98+% | 50g |
￥779.00 | 2023-03-03 |
4-Dimethylamino Antipyrine, chemically known as 4-(dimethylamino)phenol, is a significant compound in the field of pharmaceutical chemistry and biochemical research. With a CAS number of 58-15-1, this aromatic heterocyclic amine has garnered considerable attention due to its versatile applications and structural properties. The compound belongs to the phenol derivative family, characterized by a pyridine-like structure with a dimethylamino substituent at the para position relative to the hydroxyl group.
The molecular formula of 4-Dimethylamino Antipyrine is C11H13N1O, reflecting its composition of 11 carbon atoms, 13 hydrogen atoms, one nitrogen atom, and one oxygen atom. This molecular configuration contributes to its unique chemical reactivity and solubility characteristics, making it a valuable intermediate in synthetic organic chemistry. The presence of both hydroxyl and dimethylamino functional groups allows for diverse chemical modifications, enabling the synthesis of various pharmacologically active derivatives.
In recent years, 4-Dimethylamino Antipyrine has been extensively studied for its potential in medicinal chemistry. Its structural framework closely resembles that of classical antipyretic and analgesic agents, such as phenacetin and its analogs. However, the addition of the dimethylamino group enhances its pharmacological profile, particularly in terms of metabolic stability and binding affinity to biological targets. This modification has opened new avenues for developing novel therapeutic agents with improved efficacy and reduced side effects.
One of the most compelling aspects of 4-Dimethylamino Antipyrine is its role as a precursor in the synthesis of bioactive molecules. Researchers have leveraged its reactive sites to develop compounds with anti-inflammatory, antimicrobial, and even anticancer properties. For instance, recent studies have demonstrated that derivatives of 4-Dimethylamino Antipyrine exhibit significant inhibitory effects on certain enzymes implicated in chronic inflammatory diseases. These findings underscore the compound's potential as a scaffold for drug discovery initiatives targeting complex pathological conditions.
The pharmacokinetic behavior of 4-Dimethylamino Antipyrine has also been a subject of intense investigation. Its moderate solubility in both aqueous and organic solvents facilitates its use in formulation development for various delivery systems. Additionally, preliminary toxicological studies suggest that the compound exhibits low acute toxicity at therapeutic doses, making it a promising candidate for further clinical development. However, comprehensive safety evaluations are still necessary to fully assess its long-term viability in pharmaceutical applications.
Advances in computational chemistry have further enhanced the understanding of 4-Dimethylamino Antipyrine's interactions with biological targets. Molecular modeling studies have identified key binding pockets on proteins relevant to pain perception and inflammation modulation. These insights have guided the rational design of optimized derivatives with enhanced receptor affinity and selectivity. Such targeted modifications are critical for minimizing off-target effects and improving overall therapeutic outcomes.
The synthesis methodologies for 4-Dimethylamino Antipyrine have also seen significant refinement over the years. Modern synthetic routes now emphasize efficiency, scalability, and environmental sustainability. Catalytic processes and green chemistry principles have been integrated into production protocols to reduce waste generation and energy consumption. These advancements not only improve cost-effectiveness but also align with global efforts toward sustainable chemical manufacturing.
In conclusion,4-Dimethylamino Antipyrine (CAS No: 58-15-1) represents a cornerstone compound in pharmaceutical research due to its structural versatility and pharmacological promise. Its role as a precursor for bioactive derivatives continues to drive innovation in drug discovery programs targeting inflammation-related disorders. As research progresses, it is anticipated that new applications for this compound will emerge, further solidifying its importance in modern medicinal chemistry.
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