Cas no 574-64-1 (Trypan red)
Trypan red Chemical and Physical Properties
Names and Identifiers
-
- 2,7-Naphthalenedisulfonicacid,4,4'-[(3-sulfo[1,1'-biphenyl]-4,4'-diyl)bis(2,1-diazenediyl)]bis[3-amino-,sodium salt (1:5)
- 2,7-Naphthalenedisulfonicacid,4,4'-[(3-sulfo[1,1'-biphenyl]-4,4'-diyl)bis(2,1-diazenediyl)]bis...
- C.I. 22850
- pentasodium,3-amino-4-[[4-[4-[(2-amino-3,6-disulfonatonaphthalen-1-yl)diazenyl]-3-sulfonatophenyl]phenyl]diazenyl]naphthalene-2,7-disulfonate
- TRYPAN RED
- TRYPAN RED PLUS? *0.1 M AQUEOUS SOLUTION*
- 4,4'-[(3-sulfo[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[3-amino-2,7-naphthalenedisulfonic acid] pentasodium salt
- EINECS 209-372-0
- Trypanrot
- Pentasodium 4,4'-[(3-sulphonato[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[3-aminonaphthalene-2,7-disulphonate]
- UNII-2549SX0N51
- CS-8119
- HY-D0983
- 3-amino-4-[(E)-[4-[4-[(E)-(2-amino-3,6-disulfo-1-naphthyl)azo]-3-sulfo-phenyl]phenyl]azo]naphthalene-2,7-disulfonic acid
- Biphenyl-3-sulfonsaeure-4,4'-bis(1-azo-2-amino-3,6-naphthyldisulfonsaeure) pentanatriumsalz
- NSC11243
- DTXSID601024130
- 2549SX0N51
- Q2456812
- TRYPAN RED [WHO-DD]
- 2,7-Naphthalenedisulfonic acid, 4,4'-((3-sulfo(1,1'-biphenyl)-4,4'-diyl)bis(azo))bis(3-amino-, pentasodium salt
- 574-64-1
- 2,7-Naphthalenedisulfonic acid, 4,4'-((3-sulfo-4,4'-biphenylylene)bis(azo))bis(3-amino-, pentasodium salt
- Pentasodium 4,4'-((3-sulphonato(1,1'-biphenyl)-4,4'-diyl)bis(azo))bis(3-aminonaphthalene-2,7-disulphonate)
- TRYPANRED
- CI-22850
- 4,4'-(3-Sulfo-4,4'-biphenylylenbiazo)bis(3-amino-2,7-naphthalindisulfonsaeure) pentanatriumsalz
- TRYPAN RED [MI]
- 4,4'-[(3-Sulfo[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[3-amino-2,7-naphthalenedisulfonic acid, Pentasodium salt
- NS00042881
- Sodium 4,4'-((3-sulfonato-[1,1'-biphenyl]-4,4'-diyl)bis(diazene-2,1-diyl))bis(3-aminonaphthalene-2,7-disulfonate)
- pentasodium;3-amino-4-[[4-[4-[(2-amino-3,6-disulfonatonaphthalen-1-yl)diazenyl]-3-sulfonatophenyl]phenyl]diazenyl]naphthalene-2,7-disulfonate
- 4,4'-((3-SULFO(1,1'-BIPHENYL)-4,4'-DIYL)BIS(2,1-DIAZENEDIYL))BIS(3-AMINO-2,7-NAPHTHALENEDISULFONIC ACID) SODIUM SALT (1:5)
- 3-amino-4-[[4-[4-[(2-amino-3,6-disulfonaphthalen-1-yl)diazenyl]-3-sulfophenyl]phenyl]diazenyl]naphthalene-2,7-disulfonic acid
- C.I.-22850
- NSC 11243
- RBDJQFKUZPMOFH-UHFFFAOYSA-I
- DA-58780
- Trypan red
-
- Inchi： 1S/C32H24N6O15S5.5Na/c33-29-27(57(48,49)50)14-18-11-21(54(39,40)41)6-8-23(18)31(29)37-35-20-4-1-16(2-5-20)17-3-10-25(26(13-17)56(45,46)47)36-38-32-24-9-7-22(55(42,43)44)12-19(24)15-28(30(32)34)58(51,52)53;;;;;/h1-15H,33-34H2,(H,39,40,41)(H,42,43,44)(H,45,46,47)(H,48,49,50)(H,51,52,53);;;;;/q;5*+1/p-5/b37-35+,38-36+;;;;;
- InChI Key： RBDJQFKUZPMOFH-DDUJJQHXSA-I
- SMILES： S(C1C=C2C=C(C=CC2=C(C=1N)/N=N/C1C=CC(=CC=1S(=O)(=O)[O-])C1C=CC(=CC=1)/N=N/C1C(=C(C=C2C=C(C=CC2=1)S(=O)(=O)[O-])S(=O)(=O)[O-])N)S(=O)(=O)[O-])(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+].[Na+]
Computed Properties
- Exact Mass: 1001.90000
- Monoisotopic Mass: 1001.9000412g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 21
- Heavy Atom Count: 63
- Rotatable Bond Count: 10
- Complexity: 2040
- Covalently-Bonded Unit Count: 6
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: 3
- XLogP3: nothing
- Topological Polar Surface Area: 429?2
Experimental Properties
- Color/Form: Solid
- PSA: 429.38000
- LogP: 10.74210
Trypan red Security Information
- Signal Word：warning
- Hazard Statement： H303 may be harmful by ingestion +h313 may be harmful by skin contact +h2413 may be harmful by inhalation
-
Warning Statement：
P264 wash thoroughly after treatment
p280 wear protective gloves / wear protective clothing / wear protective eye masks / wear protective masks
p305 if in eyes
p351 rinse carefully with water for a few minutes
p338 remove contact lenses (if any) and easy to operate, continue rinsing
p337 if eye irritation persists
p2393 get medical advice / care - Safety Instruction： H303 may be harmful by ingestion +h313 may be harmful by skin contact +h2413 may be harmful by inhalation
- Storage Condition：Please store the product under the recommended conditions in the Certificate of Analysis.
Trypan red Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| WU HAN AN JIE KAI Biomedical Technology Co., Ltd. | ajce45432-5mg |
Trypan red (C.I. 22850) |
574-64-1 | 98% | 5mg |
￥3120.00 | 2023-09-08 | |
| MedChemExpress | HY-D0983-5mg |
Trypan red |
574-64-1 | 5mg |
￥3500 | 2023-03-07 | ||
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | T912568-5mg |
Trypan red (C.I. 22850) |
574-64-1 | 98% | 5mg |
￥5,499.00 | 2022-08-31 | |
| Ambeed | A309176-5mg |
Sodium 4,4'-((3-sulfonato-[1,1'-biphenyl]-4,4'-diyl)bis(diazene-2,1-diyl))bis(3-aminonaphthalene-2,7-disulfonate) |
574-64-1 | 98% | 5mg |
$450.0 | 2025-04-18 | |
| MedChemExpress | HY-D0983-25mg |
Trypan red |
574-64-1 | 25mg |
￥567 | 2025-04-16 | ||
| MedChemExpress | HY-D0983-50mg |
Trypan red |
574-64-1 | 50mg |
￥908 | 2025-04-16 | ||
| MedChemExpress | HY-D0983-100mg |
Trypan red |
574-64-1 | 100mg |
￥1454 | 2025-04-16 |
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Trypan red Related Literature
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Jing Yu,Yu-Qi Lyu,Jiapeng Liu,Mohammed B. Effat,Junxiong Wu J. Mater. Chem. A, 2019,7, 17995-18002
-
Bo Wei,Zhenyu Liu,Chen Xie,Shu Yang,Wentao Tang,Aiwei Gu,Wing-Tak Wong,Ka-Leung Wong J. Mater. Chem. C, 2015,3, 12322-12327
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Weili Dai,Guangjun Wu,Michael Hunger Chem. Commun., 2015,51, 13779-13782
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Min Kim,Jae-Joon Lee,Tengling Ye,Panagiotis E. Keivanidis,Kilwon Cho J. Mater. Chem. C, 2020,8, 1686-1696
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Gaurav J. Shah,Eric P.-Y. Chiou,Ming C. Wu,Chang-Jin “CJ” Kim Lab Chip, 2009,9, 1732-1739
Additional information on Trypan red
Trypan Red (CAS No. 574-64-1): An Overview of Its Properties, Applications, and Recent Research
Trypan Red, also known as CAS No. 574-64-1, is a vital compound in the field of biochemistry and cell biology. This azo dye is widely recognized for its ability to distinguish between live and dead cells, making it an essential tool in various research and diagnostic applications. In this comprehensive overview, we will delve into the properties, applications, and recent research advancements of Trypan Red.
Chemical Properties: Trypan Red is a synthetic azo dye with the chemical formula C20H18N2O3S. It is a deep red powder that is soluble in water and ethanol. The compound's unique structure allows it to interact with cell membranes, making it an effective stain for cell viability assays. The molecular weight of Trypan Red is approximately 358.43 g/mol.
Mechanism of Action: The primary mechanism by which Trypan Red functions is through its ability to penetrate damaged or dead cells while being excluded by live cells with intact membranes. This property makes it an excellent indicator of cell viability. When a cell is dead or damaged, the dye enters the cell and binds to intracellular components, causing the cell to appear red under a microscope. Live cells, on the other hand, exclude the dye and remain unstained.
Applications in Cell Biology: One of the most common applications of Trypan Red is in cell viability assays. Researchers use it to quickly and accurately determine the percentage of live and dead cells in a sample. This method is particularly useful in evaluating the effects of various treatments, such as drugs or toxins, on cell health. Additionally, Trypan Red can be used in combination with other dyes to provide more detailed information about cell morphology and function.
Clinical Applications: Beyond research, Trypan Red has found applications in clinical settings as well. For instance, it is used in blood banking to assess the viability of stored red blood cells before transfusion. This ensures that only healthy cells are used, reducing the risk of complications for patients receiving transfusions.
Recent Research Developments: Recent studies have explored new applications and improvements for Trypan Red. One notable area of research involves using Trypan Red in combination with other imaging techniques to enhance the accuracy of cell viability assessments. For example, a study published in the Journal of Cell Science demonstrated that combining Trypan Red with fluorescence microscopy can provide more detailed insights into cellular processes.
In another study, researchers investigated the use of Trypan Red in high-throughput screening (HTS) platforms for drug discovery. The results showed that Trypan Red-based assays can be effectively integrated into HTS workflows to rapidly identify compounds that affect cell viability. This has significant implications for developing new therapeutic agents.
Safety Considerations: strong>< strong >While< strong > Trypan Red< strong >is generally considered safe for use in laboratory settings, proper handling and disposal protocols should be followed to ensure safety. Researchers should wear appropriate personal protective equipment (PPE) and handle the compound in a well-ventilated area to minimize exposure risks. p > < p >< strong >Conclusion:< strong > Trypan Red (CAS No.< strong > 574-64-1< strong >) remains a crucial tool in biochemistry and cell biology due to its unique properties and wide range of applications. Ongoing research continues to expand its utility and improve its effectiveness in various fields, from basic research to clinical diagnostics.< / p > article > response >
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