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• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Diazines Aminopyrimidines and derivatives
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Diazines Pyrimidines and pyrimidine derivatives Aminopyrimidines and derivatives

4-Methyl-6-(trifluoromethyl)pyrimidin-2-amine (CAS No. 5734-63-4): A Comprehensive Overview

The compound 4-Methyl-6-(trifluoromethyl)pyrimidin-2-amine, identified by the CAS registry number CAS No. 5734-63-4, is a heterocyclic aromatic amine with significant applications in various fields of chemistry and pharmacology. This molecule, belonging to the pyrimidine family, has attracted considerable attention due to its unique structural features and versatile functional groups. The presence of a methyl group at position 4 and a trifluoromethyl group at position 6 imparts distinct electronic and steric properties, making it a valuable substrate for further chemical modifications and biological studies.

Recent advancements in synthetic chemistry have enabled the efficient synthesis of 4-Methyl-6-(trifluoromethyl)pyrimidin-2-amine. Researchers have employed various methodologies, including nucleophilic aromatic substitution and transition metal-catalyzed coupling reactions, to construct this compound with high yield and purity. These methods not only highlight the molecule's synthetic accessibility but also underscore its potential as a building block in drug discovery and material science.

In the realm of pharmacology, 4-Methyl-6-(trifluoromethyl)pyrimidin-2-amine has demonstrated promising bioactivity in preclinical studies. Its ability to modulate key biological targets, such as kinases and receptors, positions it as a potential candidate for therapeutic development. Recent studies have explored its role in anti-cancer drug design, where it has shown selective inhibition against certain oncogenic pathways. Additionally, its trifluoromethyl group contributes to enhanced metabolic stability, a critical factor in drug efficacy.

The structural versatility of CAS No. 5734-63-4 extends to its application in materials science. By incorporating this compound into polymer systems, researchers have developed advanced materials with improved thermal stability and electronic properties. These materials hold potential for use in high-performance electronics and energy storage devices.

In conclusion, 4-Methyl-6-(trifluoromethyl)pyrimidin-2-amine, with its unique chemical structure and diverse functional groups, continues to be a focal point in contemporary research. Its applications span across synthetic chemistry, pharmacology, and materials science, underscoring its significance as a multifaceted compound. As ongoing studies unravel its full potential, this compound is poised to make substantial contributions to both academic and industrial advancements.

• 238742-83-1(4-(tert-Butyl)-6-(trifluoromethyl)pyrimidin-2-amine)
• 136547-16-5(4-(Trifluoromethyl)pyrimidine)
• 16075-42-6(4-(trifluoromethyl)pyrimidin-2-amine)
• 26974-09-4(2-Amino-4-phenyl-6-(trifluoromethyl)pyrimidine)
• 92311-42-7(2-Pyrimidinamine,4-(fluoromethyl)-6-methyl-)
• 197305-97-8(2-Hydrazino-4-(trifluoromethyl)pyrimidine)
• 71999-94-5(1,2-bis[4-methyl-6-(trifluoromethyl)pyrimidin-2-yl]hydrazine)
• 1193721-39-9(N-Methyl-4-(trifluoromethyl)pyrimidin-2-amine)
• 215655-29-1(N1-4-(Trifluoromethyl)-2-pyrimidinyl-1,2-ethanediamine)
• 123024-52-2(2-Hydrazino-4-methyl-6-(trifluoromethyl)pyrimidine)