Cas no 57332-84-0 (Ethyl a-Bromoethylglyoxalate)

Ethyl α-Bromoethylglyoxalate is a versatile brominated ester compound widely used in organic synthesis, particularly in the preparation of heterocycles and as an intermediate in pharmaceutical and agrochemical applications. Its reactive α-bromo and glyoxalate moieties enable efficient nucleophilic substitutions and cyclization reactions, making it valuable for constructing complex molecular frameworks. The compound offers high reactivity and selectivity, facilitating streamlined synthetic routes. It is typically handled under controlled conditions due to its sensitivity to moisture and light. Ethyl α-Bromoethylglyoxalate is favored for its ability to introduce functionalized ethylglyoxalate groups into target molecules, enhancing modularity in synthetic design. Proper storage and handling are essential to maintain stability.
Ethyl a-Bromoethylglyoxalate structure
Ethyl a-Bromoethylglyoxalate structure
Product Name:Ethyl a-Bromoethylglyoxalate
CAS No:57332-84-0
MF:C6H9BrO3
MW:209.037861585617
MDL:MFCD19440735
CID:1011707
PubChem ID:11117285
Update Time:2025-10-28

Ethyl a-Bromoethylglyoxalate Chemical and Physical Properties

Names and Identifiers

    • 3-Bromo-2-oxo-butyric acid ethyl ester
    • Ethyl α-Bromoethylglyoxalate
    • ethyl 2-oxo-3-bromobutyrate
    • Ethyl 3-bromo-2-oxobutanoate
    • Ethyl 3-bromo-2-oxobutyrate
    • ethyl 3-bromo-2-oxovalerate
    • ethyl dl-3-bromo-2-oxobutyrate
    • methyl ethyl bromopyruvate
    • QC-10762
    • 3-Bromo-2-oxobutanoic acid ethyl ester
    • Butanoic acid, 3-bromo-2-oxo-, ethyl ester
    • Ethyl
    • A-Bromoethylglyoxalate
    • Ethyl-3-bromo-2-oxobutanoate
    • SIOIQIWIQSMQAG-UHFFFAOYSA-N
    • 5871AE
    • WT82069
    • 2-Oxo-3-bromobutyric acid ethyl ester
    • AB0093519
    • ST2404936
    • 4CH
    • CS-W006537
    • Ethyl alpha-Bromoethylglyoxalate
    • AKOS015997948
    • DS-15483
    • EN300-126200
    • DTXSID00455814
    • 57332-84-0
    • SCHEMBL114311
    • SY105905
    • Ethyl a-Bromoethylglyoxalate
    • 3-bromo-2-oxo-butyricacidethylester
    • AMY202100100
    • DB-017468
    • MFCD19440735
    • ALBB-022331
    • MDL: MFCD19440735
    • Inchi: 1S/C6H9BrO3/c1-3-10-6(9)5(8)4(2)7/h4H,3H2,1-2H3
    • InChI Key: SIOIQIWIQSMQAG-UHFFFAOYSA-N
    • SMILES: BrC(C)C(C(=O)OCC)=O

Computed Properties

  • Exact Mass: 207.97351g/mol
  • Monoisotopic Mass: 207.97351g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 3
  • Heavy Atom Count: 10
  • Rotatable Bond Count: 4
  • Complexity: 144
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 1
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 43.4
  • XLogP3: 1.6

Experimental Properties

  • Color/Form: No data avaiable
  • Density: 1.474
  • Melting Point: No data available
  • Boiling Point: 213 oC
  • Flash Point: 83 oC
  • PSA: 43.37000
  • LogP: 0.90200
  • Vapor Pressure: 0.2±0.4 mmHg at 25°C

Ethyl a-Bromoethylglyoxalate Pricemore >>

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Additional information on Ethyl a-Bromoethylglyoxalate

Ethyl a-Bromoethylglyoxalate: A Comprehensive Overview

Ethyl a-Bromoethylglyoxalate, with the CAS number 57332-84-0, is a chemical compound that has garnered significant attention in recent years due to its unique properties and diverse applications. This compound, often referred to as Ethyl a-Bromoethylglyoxalate, belongs to the class of glyoxalates and is characterized by its brominated structure, which imparts distinctive reactivity and functionality. The compound's structure consists of a glyoxalate backbone with an ethyl group attached to the alpha position of the bromoethyl moiety, making it a valuable intermediate in organic synthesis.

Recent studies have highlighted the importance of Ethyl a-Bromoethylglyoxalate in various fields, including pharmaceuticals, agrochemicals, and materials science. Its ability to undergo nucleophilic substitution reactions has made it a key intermediate in the synthesis of bioactive molecules. For instance, researchers have utilized this compound to synthesize novel antibiotics and antifungal agents, leveraging its reactivity to create compounds with enhanced potency and selectivity.

The synthesis of Ethyl a-Bromoethylglyoxalate typically involves multi-step processes that require precise control over reaction conditions. One common approach involves the bromination of ethyl glyoxalate derivatives, followed by subsequent purification steps to ensure high purity. The compound's stability under various conditions has been extensively studied, with findings indicating that it is relatively stable under normal storage conditions but may decompose under harsh thermal or oxidative environments.

In terms of applications, Ethyl a-Bromoethylglyoxalate has found significant use in the development of advanced materials. Its ability to form stable covalent bonds makes it an ideal candidate for cross-linking polymers and developing high-performance adhesives. Recent advancements in polymer chemistry have demonstrated how this compound can be used to create materials with improved mechanical properties and thermal stability.

Another area where Ethyl a-Bromoethylglyoxalate has shown promise is in catalysis. Researchers have explored its potential as a catalyst in various organic reactions, particularly those involving nucleophilic substitution and addition mechanisms. Its role as a catalyst has been validated through numerous experiments, where it has been shown to significantly accelerate reaction rates while maintaining high selectivity.

From an environmental perspective, understanding the fate and transport of Ethyl a-Bromoethylglyoxalate is crucial for ensuring its safe use and disposal. Studies have indicated that the compound undergoes biodegradation under aerobic conditions, with microbial activity playing a significant role in its breakdown. However, further research is needed to fully characterize its environmental impact and develop strategies for minimizing ecological risks.

In conclusion, Ethyl a-Bromoethylglyoxalate (CAS No: 57332-84-0) is a versatile compound with wide-ranging applications across multiple disciplines. Its unique chemical properties make it an invaluable tool in organic synthesis, catalysis, and materials science. As research continues to uncover new potential uses for this compound, it is likely to play an even more prominent role in advancing scientific and technological innovations.

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